The regulation of sarco(endo)plasmic reticulum calcium-ATPases (SERCA)

Sarcolipin Provides a Novel Muscle-Based Mechanism for Adaptive Thermogenesis

(2014) Daniel Gamu et al.   EXERCISE AND SPORT SCIENCES REVIEWS

Differential regulation of the fiber type-specific gene expression of the sarcoplasmic reticulum calcium-ATPase isoforms induced by exercise training

(2014) Marc P. Morissette et al.   JOURNAL OF APPLIED PHYSIOLOGY

Inhibition of miR-25 improves cardiac contractility in the failing heart

(2014) Christine Wahlquist et al.   NATURE

SERCA2a: a prime target for modulation of cardiac contractility during heart failure

(2013) Woo Jin Park et al.   BMB Reports

Long-Term Effects of AAV1/SERCA2a Gene Transfer in Patients With Severe Heart Failure

(2013) Krisztina Zsebo et al.   CIRCULATION RESEARCH

Increased Sarcolipin Expression and Adrenergic Drive in Humans With Preserved Left Ventricular Ejection Fraction and Chronic Isolated Mitral Regurgitation

(2013) Junying Zheng et al.   Circulation-Heart Failure

Modulation of Skeletal Muscle Performance and SERCA by Exercise and Adiponectin Gene Therapy in Insulin-Resistant Rat

(2013) Yasmeen Safwat et al.   DNA AND CELL BIOLOGY

Ablation of sarcolipin decreases the energy requirements for Ca2+transport by sarco(endo)plasmic reticulum Ca2+-ATPases in resting skeletal muscle

(2013) Eric Bombardier et al.   FEBS LETTERS

Sarcolipin Protein Interaction with Sarco(endo)plasmic Reticulum Ca2+ATPase (SERCA) Is Distinct from Phospholamban Protein, and Only Sarcolipin Can Promote Uncoupling of the SERCA Pump

(2013) Sanjaya K. Sahoo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Globular Adiponectin Attenuates Myocardial Ischemia/Reperfusion Injury by Upregulating Endoplasmic Reticulum Ca2+-ATPase Activity and Inhibiting Endoplasmic Reticulum Stress

(2013) Jia Guo et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

The benefits of endurance training in cardiomyocyte function in hypertensive rats are reversed within four weeks of detraining

(2013) Miguel Araujo Carneiro-Júnior et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

ATP Consumption by Sarcoplasmic Reticulum Ca2+ Pumps Accounts for 40-50% of Resting Metabolic Rate in Mouse Fast and Slow Twitch Skeletal Muscle

(2013) Ian Curtis Smith et al.   PLoS One

The Cardiac Acetyl-Lysine Proteome

(2013) D. Brian Foster et al.   PLoS One

SUMO-1 Gene Transfer Improves Cardiac Function in a Large-Animal Model of Heart Failure

(2013) L. Tilemann et al.   Science Translational Medicine

Is the lack of adiponectin associated with increased ER/SR stress and inflammation in the heart?

(2013) Neeraja J Boddu et al.   Adipocyte

Regulation of the alternative splicing of sarcoplasmic reticulum Ca2+-ATPase1 (SERCA1) by phorbol 12-myristate 13-acetate (PMA) via a PKC pathway

(2012) Yimeng Zhao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Adiponectin: Anti-inflammatory and cardioprotective effects

(2012) M.T. Villarreal-Molina et al.   BIOCHIMIE

Up-regulation of sarcoplasmic reticulum Ca2+ uptake leads to cardiac hypertrophy, contractile dysfunction and early mortality in mice deficient in CASQ2

(2012) Anuradha Kalyanasundaram et al.   CARDIOVASCULAR RESEARCH

Targeted Deletion of MicroRNA-22 Promotes Stress-Induced Cardiac Dilation and Contractile Dysfunction

(2012) Priyatansh Gurha et al.   CIRCULATION

SERCA2a gene therapy restores microRNA-1 expression in heart failure via an Akt/FoxO3A-dependent pathway

(2012) Regalla Kumarswamy et al.   EUROPEAN HEART JOURNAL

3-Bromopyruvate inhibits calcium uptake by sarcoplasmic reticulum vesicles but not SERCA ATP hydrolysis activity

(2012) Douglas Jardim-Messeder et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Specific effects of endurance and sprint training on protein expression of calsequestrin and SERCA in mouse skeletal muscle

(2012) Sanni Kinnunen et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

Exercise training mitigates aberrant cardiac protein O-GlcNAcylation in streptozotocin-induced diabetic mice

(2012) Catherine E. Bennett et al.   LIFE SCIENCES

Hsp72 preserves muscle function and slows progression of severe muscular dystrophy

(2012) Stefan M. Gehrig et al.   NATURE

Sarcolipin is a newly identified regulator of muscle-based thermogenesis in mammals

(2012) Naresh C Bal et al.   NATURE MEDICINE

Novel therapies in acute and chronic heart failure

(2012) Doron Aronson et al.   PHARMACOLOGY & THERAPEUTICS

Enhanced cardiac protein glycosylation (O-GlcNAc) of selected mitochondrial proteins in rats artificially selected for low running capacity

(2012) Virginia L. Johnsen et al.   PHYSIOLOGICAL GENOMICS

Emerging characterization of the role of SIRT3-mediated mitochondrial protein deacetylation in the heart

(2011) Michael N. Sack   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Malleability of human skeletal muscle sarcoplasmic reticulum to short-term training

(2011) Howard J. Green et al.   Applied Physiology Nutrition and Metabolism

Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID)

(2011) Mariell Jessup et al.   CIRCULATION

Swim-exercised mice show a decreased level of protein O-GlcNAcylation and expression of O-GlcNAc transferase in heart

(2011) Darrell D. Belke   JOURNAL OF APPLIED PHYSIOLOGY

SUMO1-dependent modulation of SERCA2a in heart failure

(2011) Changwon Kho et al.   NATURE

Cardiac contractile dysfunction during acute hyperglycemia due to impairment of SERCA by polyol pathway-mediated oxidative stress

(2010) Wai Ho Tang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Mitochondrial transcription factors TFAM and TFB2M regulate Serca2 gene transcription

(2010) Atai Watanabe et al.   CARDIOVASCULAR RESEARCH

Inhibition of phospholamban phosphorylation by O-GlcNAcylation: implications for diabetic cardiomyopathy

(2010) S. Yokoe et al.   GLYCOBIOLOGY

Role of glycogen availability in sarcoplasmic reticulum Ca2+kinetics in human skeletal muscle

(2010) Niels Ørtenblad et al.   JOURNAL OF PHYSIOLOGY-LONDON

Endurance training reverts heart mitochondrial dysfunction, permeability transition and apoptotic signaling in long-term severe hyperglycemia

(2010) José Lumini-Oliveira et al.   MITOCHONDRION

Obesogenic high fat western diet induces oxidative stress and apoptosis in rat heart

(2010) Kalpana Ballal et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Differential Regulation of HIC1 Target Genes by CtBP and NuRD, via an Acetylation/SUMOylation Switch, in Quiescent versus Proliferating Cells

(2010) C. Van Rechem et al.   MOLECULAR AND CELLULAR BIOLOGY

Training response of mitochondrial transcription factors in human skeletal muscle

(2009) J. Norrbom et al.   Acta Physiologica

Cardioprotective effect of adiponectin is partially mediated by its AMPK-independent antinitrative action

(2009) Yajing Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Resveratrol, an activator of SIRT1, upregulates sarcoplasmic calcium ATPase and improves cardiac function in diabetic cardiomyopathy

(2009) M. Sulaiman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Nitroxyl Activates SERCA in Cardiac Myocytes via Glutathiolation of Cysteine 674

(2009) Steve Lancel et al.   CIRCULATION RESEARCH

Moderate intensity of regular exercise improves cardiac SR Ca2+ uptake activity in ovariectomized rats

(2009) Tepmanas Bupha-Intr et al.   JOURNAL OF APPLIED PHYSIOLOGY

Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID Trial), a First-in-Human Phase 1/2 Clinical Trial

(2009) Brian E. Jaski et al.   JOURNAL OF CARDIAC FAILURE

Threonine-5 at the N-terminus can modulate sarcolipin function in cardiac myocytes

(2009) Poornima Bhupathy et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Alterations in mitochondrial function and cytosolic calcium induced by hyperglycemia are restored by mitochondrial transcription factor A in cardiomyocytes

(2008) Jorge Suarez et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Rescue of Ca2+ overload-induced left ventriclur dysfunction by targeted ablation of phospholamban

(2008) Tsuyoshi Tsuji et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Conditional increase in SERCA2a protein is able to reverse contractile dysfunction and abnormal calcium flux in established diabetic cardiomyopathy

(2008) Jorge Suarez et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

How Ca2+-ATPase pumps ions across the sarcoplasmic reticulum membrane

(2008) Chikashi Toyoshima   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Myocardial sarcoplasmic reticulum Ca2+ ATPase function is increased by aerobic interval training

(2008) Ole Johan Kemi et al.   EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION & REHABILITATION

Hemodynamic, Echocardiographic, and Neurohormonal Effects of Istaroxime, a Novel Intravenous Inotropic and Lusitropic Agent

(2008) Mihai Gheorghiade et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Effects of Exercise on Adiponectin: A Systematic Review

(2008) Kylie A. Simpson et al.   Obesity

The cardiac sarcoplasmic/endoplasmic reticulum calcium ATPase: a potent target for cardiovascular diseases

(2008) Yoshiaki Kawase et al.   Nature clinical practice. Cardiovascular medicine

High glucose oxidizes SERCA cysteine-674 and prevents inhibition by nitric oxide of smooth muscle cell migration

(2007) XiaoYong Tong et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY