Enabling formulations of aprepitant: in vitro and in vivo comparison of nanocrystalline, amorphous and deep eutectic solvent based formulations
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Title
Enabling formulations of aprepitant: in vitro and in vivo comparison of nanocrystalline, amorphous and deep eutectic solvent based formulations
Authors
Keywords
Bioavailability, Poorly soluble drugs, Deep eutectic solvents, Supersaturation, Amorphous, Nanocrystalline
Journal
International Journal of Pharmaceutics: X
Volume 3, Issue -, Pages 100083
Publisher
Elsevier BV
Online
2021-06-05
DOI
10.1016/j.ijpx.2021.100083
References
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Note: Only part of the references are listed.- Comparison of induction methods for supersaturation: Amorphous dissolution versus solvent shift
- (2020) Jakob Plum et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Effect of supersaturation on absorption of indomethacin and tadalafil in a single pass intestinal perfusion rat model, in the absence and presence of a precipitation inhibitor
- (2020) Sophie Strindberg et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Influence of water of crystallization on the ternary phase behavior of a drug and deep eutectic solvent
- (2020) Henrik Palmelund et al. JOURNAL OF MOLECULAR LIQUIDS
- Deep Eutectic Solvents: A Review of Fundamentals and Applications
- (2020) Benworth B. Hansen et al. CHEMICAL REVIEWS
- High-Throughput Dissolution/Permeation Screening —A 96-Well Two-Compartment Microplate Approach
- (2019) Jacobsen et al. Pharmaceutics
- Impacts of particle shapes on the oral delivery of drug nanocrystals: Mucus permeation, transepithelial transport and bioavailability
- (2019) Mengran Guo et al. JOURNAL OF CONTROLLED RELEASE
- Combining biorelevant in vitro and in silico tools to simulate and better understand the in vivo performance of a nano-sized formulation of aprepitant in the fasted and fed states
- (2019) Chara Litou et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- The Role of Polyfunctionality in the Formation of [Ch]Cl-carboxylic acid-based DES
- (2018) Emanuel Almeida Crespo et al. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
- Is there a correlation between the glass forming ability of a drug and its supersaturation propensity?
- (2018) Lasse Ingerslev Blaabjerg et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Jejunal absorption of aprepitant from nanosuspensions: role of particle size, prandial state and mucus layer
- (2018) C. Roos et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Insights into the Nature of Eutectic and Deep Eutectic Mixtures
- (2018) Mónia A. R. Martins et al. JOURNAL OF SOLUTION CHEMISTRY
- Mechanistic modelling of intestinal drug absorption – The in vivo effects of nanoparticles, hydrodynamics, and colloidal structures
- (2018) C. Roos et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- In Vivo Mechanisms of Intestinal Drug Absorption from Aprepitant Nanoformulations
- (2017) Carl Roos et al. MOLECULAR PHARMACEUTICS
- The solubility–permeability interplay and oral drug formulation design: Two heads are better than one
- (2016) Arik Dahan et al. ADVANCED DRUG DELIVERY REVIEWS
- Investigation on drug solubility enhancement using deep eutectic solvents and their derivatives
- (2016) Zheng Li et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Supersaturation and Precipitation of Posaconazole Upon Entry in the Upper Small Intestine in Humans
- (2016) Bart Hens et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Studying the Propensity of Compounds to Supersaturate: A Practical and Broadly Applicable Approach
- (2016) Henrik Palmelund et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Significantly improving the solubility of non-steroidal anti-inflammatory drugs in deep eutectic solvents for potential non-aqueous liquid administration
- (2016) Chao Lu et al. MedChemComm
- Tailoring properties of natural deep eutectic solvents with water to facilitate their applications
- (2015) Yuntao Dai et al. FOOD CHEMISTRY
- Characterization and Pharmacokinetic Study of Aprepitant Solid Dispersions with Soluplus®
- (2015) Jinwen Liu et al. MOLECULES
- Deep Eutectic Solvents (DESs) and Their Applications
- (2014) Emma L. Smith et al. CHEMICAL REVIEWS
- Deep eutectic solvents: syntheses, properties and applications
- (2012) Qinghua Zhang et al. CHEMICAL SOCIETY REVIEWS
- Drug precipitation–permeation interplay: Supersaturation in an absorptive environment
- (2012) Jan Bevernage et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Evaluation of gastrointestinal drug supersaturation and precipitation: Strategies and issues
- (2012) Jan Bevernage et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Development of aprepitant, the first neurokinin-1 receptor antagonist for the prevention of chemotherapy-induced nausea and vomiting
- (2011) Richard Hargreaves et al. Annals of the New York Academy of Sciences
- Supersaturation–Nucleation Behavior of Poorly Soluble Drugs and its Impact on the Oral Absorption of Drugs in Thermodynamically High-Energy Forms
- (2011) Shunsuke Ozaki et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Excipient-Mediated Supersaturation Stabilization in Human Intestinal Fluids
- (2011) Jan Bevernage et al. MOLECULAR PHARMACEUTICS
- Forecasting in vivo oral absorption and food effect of micronized and nanosized aprepitant formulations in humans
- (2010) Yasushi Shono et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Characterization of thermal behavior of deep eutectic solvents and their potential as drug solubilization vehicles
- (2009) Henry G. Morrison et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Packing polymorphism of a conformationally flexible molecule (aprepitant)
- (2008) Doris E. Braun et al. NEW JOURNAL OF CHEMISTRY
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