Continuous production of itraconazole-based solid dispersions by hot melt extrusion: Preformulation, optimization and design space determination

Published 2016 View Full Article

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Title
Continuous production of itraconazole-based solid dispersions by hot melt extrusion: Preformulation, optimization and design space determination
Authors
Keywords
Amorphous solid dispersions, Itraconazole, Solubility enhancement, Design of experiments, Design space determination
Journal
INTERNATIONAL JOURNAL OF PHARMACEUTICS
Volume 515, Issue 1-2, Pages 114-124
Publisher
Elsevier BV
Online
2016-10-09
DOI
10.1016/j.ijpharm.2016.10.003

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