Statistical analysis and comparison of a continuous high shear granulator with a twin screw granulator: Effect of process parameters on critical granule attributes and granulation mechanisms

Title
Statistical analysis and comparison of a continuous high shear granulator with a twin screw granulator: Effect of process parameters on critical granule attributes and granulation mechanisms
Authors
Keywords
Continuous manufacturing, High shear granulation, Twin screw granulation, Design of experiments, Design space, Granulation mechanism
Journal
INTERNATIONAL JOURNAL OF PHARMACEUTICS
Volume 513, Issue 1-2, Pages 357-375
Publisher
Elsevier BV
Online
2016-09-14
DOI
10.1016/j.ijpharm.2016.09.041

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