A novel combined glucocorticoid-mineralocorticoid receptor selective modulator markedly prevents weight gain and fat mass expansion in mice fed a high-fat diet

Mineralocorticoid receptor antagonism induces browning of white adipose tissue through impairment of autophagy and prevents adipocyte dysfunction in high-fat-diet-fed mice

(2014) Andrea Armani et al.   FASEB JOURNAL

The glucocorticoid receptor, not the mineralocorticoid receptor, plays the dominant role in adipogenesis and adipokine production in human adipocytes

(2014) M-J Lee et al.   INTERNATIONAL JOURNAL OF OBESITY

Mineralocorticoid vs glucocorticoid receptors: solo players or team mates in the control of adipogenesis?

(2014) A Armani et al.   INTERNATIONAL JOURNAL OF OBESITY

Role of mineralocorticoid receptor and renin–angiotensin–aldosterone system in adipocyte dysfunction and obesity

(2013) Alessandra Feraco et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Mifepristone Promotes Adiponectin Production and Improves Insulin Sensitivity in a Mouse Model of Diet-Induced-Obesity

(2013) Takeshi Hashimoto et al.   PLoS One

Discovery of a novel non-steroidal GR antagonist with in vivo efficacy in the olanzapine-induced weight gain model in the rat

(2012) Hazel J. Hunt et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Body Composition and Cardiovascular Risk Markers after Remission of Cushing's Disease: A Prospective Study Using Whole-Body MRI

(2012) Eliza B. Geer et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Role of leptin in the pancreatic β-cell: effects and signaling pathways

(2012) Laura Marroquí et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Development of insulin resistance in mice lacking PGC-1  in adipose tissues

(2012) S. Kleiner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spironolactone Improves Glucose and Lipid Metabolism by Ameliorating Hepatic Steatosis and Inflammation and Suppressing Enhanced Gluconeogenesis Induced by High-Fat and High-Fructose Diet

(2010) Tsutomu Wada et al.   ENDOCRINOLOGY

Antiadipogenic Effects of the Mineralocorticoid Receptor Antagonist Drospirenone: Potential Implications for the Treatment of Metabolic Syndrome

(2010) Massimiliano Caprio et al.   ENDOCRINOLOGY

Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice

(2010) Patrick Seale et al.   JOURNAL OF CLINICAL INVESTIGATION

Disengaging insulin from corticosterone: roles of each on energy intake and disposition

(2009) James P. Warne et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Blockade of mineralocorticoid receptor reverses adipocyte dysfunction and insulin resistance in obese mice

(2009) Ayumu Hirata et al.   CARDIOVASCULAR RESEARCH

The balance between gluco- and mineralo-corticoid action critically determines inflammatory adipocyte responses

(2009) J Hoppmann et al.   JOURNAL OF ENDOCRINOLOGY

Mineralocorticoid Receptor Blockade Reverses Obesity-Related Changes in Expression of Adiponectin, Peroxisome Proliferator-Activated Receptor-γ, and Proinflammatory Adipokines

(2008) Christine Guo et al.   CIRCULATION