The central cannabinoid receptor type-2 (CB2) and chronic pain

Effect of cannabinoids on CGRP release in the isolated rat lumbar spinal cord

(2016) Michael Milne et al.   NEUROSCIENCE LETTERS

Evidence for brain glial activation in chronic pain patients

(2015) Marco L. Loggia et al.   BRAIN

Activated Microglia Contribute to Convergent Nociceptive Inputs to Spinal Dorsal Horn Neurons and the Development of Neuropathic Pain

(2015) Yuya Yamamoto et al.   NEUROCHEMICAL RESEARCH

Influence of nitric oxide synthase or cyclooxygenase inhibitors on cannabinoids activity in streptozotocin-induced neuropathy

(2015) Magdalena Bujalska-Zadrożny et al.   Pharmacological Reports

Mechanisms of Exercise-Induced Hypoalgesia

(2014) Kelli F. Koltyn et al.   JOURNAL OF PAIN

α-Conotoxin RgIA protects against the development of nerve injury-induced chronic pain and prevents both neuronal and glial derangement

(2014) Lorenzo Di Cesare Mannelli et al.   PAIN

Cannabinoid 2 receptor- and beta Arrestin 2-dependent upregulation of serotonin 2A receptors

(2012) J.M. Franklin et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Special Issue on microglia and chronic pain

(2012) Claire E. Hulsebosch   EXPERIMENTAL NEUROLOGY

Microglial Cathepsin B Contributes to the Initiation of Peripheral Inflammation-Induced Chronic Pain

(2012) L. Sun et al.   JOURNAL OF NEUROSCIENCE

Cannabinoid-induced enhanced interaction and protein levels of serotonin 5-HT2A and dopamine D2 receptors in rat prefrontal cortex

(2012) Jade M Franklin et al.   JOURNAL OF PSYCHOPHARMACOLOGY

CB2 receptor and amyloid pathology in frontal cortex of Alzheimer's disease patients

(2012) Maite Solas et al.   NEUROBIOLOGY OF AGING

Involvement of ERK1/2, cPLA2 and NF-κB in microglia suppression by cannabinoid receptor agonists and antagonists

(2012) Rachel Ribeiro et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Spinal cannabinoid CB2 receptors as a target for neuropathic pain: an investigation using chronic constriction injury

(2011) P.W. Brownjohn et al.   NEUROSCIENCE

Minocycline injection in the ventral posterolateral thalamus reverses microglial reactivity and thermal hyperalgesia secondary to sciatic neuropathy

(2011) Brian W. LeBlanc et al.   NEUROSCIENCE LETTERS

Antinociceptive effect of intrathecal cannabinoid receptor agonist WIN 55,212-2 in a rat bone tumor pain model

(2011) Jin Hua Cui et al.   NEUROSCIENCE LETTERS

Cannabinoid Agonists Inhibit Neuropathic Pain Induced by Brachial Plexus Avulsion in Mice by Affecting Glial Cells and MAP Kinases

(2011) Ana F. Paszcuk et al.   PLoS One

N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor

(2010) Douglas McHugh et al.   BMC NEUROSCIENCE

The direction of synaptic plasticity mediated by C-fibers in spinal dorsal horn is decided by Src-family kinases in microglia: The role of tumor necrosis factor-α

(2010) Yi Zhong et al.   BRAIN BEHAVIOR AND IMMUNITY

Spinal and peripheral analgesic effects of the CB2cannabinoid receptor agonist AM1241 in two models of bone cancer-induced pain

(2010) V Curto-Reyes et al.   BRITISH JOURNAL OF PHARMACOLOGY

Central and peripheral sites of action for CB2 receptor mediated analgesic activity in chronic inflammatory and neuropathic pain models in rats

(2010) Gin C Hsieh et al.   BRITISH JOURNAL OF PHARMACOLOGY

CB2: a cannabinoid receptor with an identity crisis

(2010) Brady K Atwood et al.   BRITISH JOURNAL OF PHARMACOLOGY

Smoked cannabis for chronic neuropathic pain: a randomized controlled trial

(2010) M. A. Ware et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

Cannabinoid-Mediated Modulation of Neuropathic Pain and Microglial Accumulation in a Model of Murine Type I Diabetic Peripheral Neuropathic Pain

(2010) Cory C Toth et al.   Molecular Pain

Spinal Microglial and Perivascular Cell Cannabinoid Receptor Type 2 Activation Reduces Behavioral Hypersensitivity without Tolerance after Peripheral Nerve Injury

(2009) Alfonso Romero-Sandoval et al.   ANESTHESIOLOGY

Cannabinoid System in Neurodegeneration: New Perspectives in Alzheimers Disease

(2009) N. Campillo et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Depression-like behaviour in rats with mononeuropathy is reduced by the CB2-selective agonist GW405833

(2009) Bing Hu et al.   PAIN

Mode of action of cannabinoids on nociceptive nerve endings

(2009) Michaela Kress et al.   EXPERIMENTAL BRAIN RESEARCH

The cannabinoid receptor agonist, WIN 55, 212-2, attenuates tumor-evoked hyperalgesia through peripheral mechanisms

(2008) Carl Potenzieri et al.   BRAIN RESEARCH

MDA7: a novel selective agonist for CB2 receptors that prevents allodynia in rat neuropathic pain models

(2008) M Naguib et al.   BRITISH JOURNAL OF PHARMACOLOGY

Gabapentin reverses microglial activation in the spinal cord of streptozotocin-induced diabetic rats

(2008) Rachel Wodarski et al.   EUROPEAN JOURNAL OF PAIN

Involvement of central cannabinoid CB2 receptor in reducing mechanical allodynia in a mouse model of neuropathic pain

(2008) Wataru Yamamoto et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Activation of dorsal horn microglia contributes to diabetes-induced tactile allodynia via extracellular signal-regulated protein kinase signaling

(2008) Makoto Tsuda et al.   GLIA

Selective Activation of Cannabinoid CB2 Receptors Suppresses Neuropathic Nociception Induced by Treatment with the Chemotherapeutic Agent Paclitaxel in Rats

(2008) E. J. Rahn et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

A CB2 receptor agonist, A-836339, modulates wide dynamic range neuronal activity in neuropathic rats: Contributions of spinal and peripheral CB2 receptors

(2008) S. McGaraughty et al.   NEUROSCIENCE

GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current

(2008) J. E. Lauckner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sch35966 is a potent, selective agonist at the peripheral cannabinoid receptor (CB2) in rodents and primates

(2007) W Gonsiorek et al.   BRITISH JOURNAL OF PHARMACOLOGY

Activation of cannabinoid CB1 and CB2 receptors suppresses neuropathic nociception evoked by the chemotherapeutic agent vincristine in rats

(2007) E J Rahn et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro

(2007) A Thomas et al.   BRITISH JOURNAL OF PHARMACOLOGY

In vitro pharmacological characterization of AM1241: a protean agonist at the cannabinoid CB2 receptor?

(2006) B B Yao et al.   BRITISH JOURNAL OF PHARMACOLOGY