S-Ketamine Rapidly Reverses Synaptic and Vascular Deficits of Hippocampus in Genetic Animal Model of Depression

Intravenous Esketamine in Adult Treatment-Resistant Depression: A Double-Blind, Double-Randomization, Placebo-Controlled Study

(2016) Jaskaran B. Singh et al.   BIOLOGICAL PSYCHIATRY

NMDAR inhibition-independent antidepressant actions of ketamine metabolites

(2016) Panos Zanos et al.   NATURE

Structural Neuroimaging Findings in Major Depressive Disorder Throughout Aging: A Critical Systematic Review of Prospective Studies

(2015) Gilberto Alves et al.   CNS & Neurological Disorders-Drug Targets

Spine synapse remodeling in the pathophysiology and treatment of depression

(2015) Catharine H. Duman et al.   NEUROSCIENCE LETTERS

Nitric oxide involvement in the antidepressant-like effect of ketamine in the Flinders sensitive line rat model of depression

(2014) Nico Liebenberg et al.   ACTA NEUROPSYCHIATRICA

Progressive alterations of hippocampal CA3-CA1 synapses in an animal model of depression

(2014) Hui Qiao et al.   BEHAVIOURAL BRAIN RESEARCH

Rapid-onset antidepressant action of ketamine: potential revolution in understanding and future pharmacologic treatment of depression

(2014) E. Drewniany et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Hippocampal volume and the rapid antidepressant effect of ketamine

(2014) Chadi G Abdallah et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Ketamine as Antidepressant? Current State and Future Perspectives

(2013) H. Hasselmann   Current Neuropharmacology

Ketamine regulates the presynaptic release machinery in the hippocampus

(2013) Heidi Kaastrup Müller et al.   JOURNAL OF PSYCHIATRIC RESEARCH

R (−)-ketamine shows greater potency and longer lasting antidepressant effects than S (+)-ketamine

(2013) Ji-chun Zhang et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Rapid antidepressant effects of repeated doses of ketamine compared with electroconvulsive therapy in hospitalized patients with major depressive disorder

(2013) Mehdi Ghasemi et al.   PSYCHIATRY RESEARCH

Hippocampal volume and total cell numbers in major depressive disorder

(2012) Justin A. Cobb et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Theo Vos et al.   LANCET

Using the rat forced swim test to assess antidepressant-like activity in rodents

(2012) David A Slattery et al.   Nature Protocols

Combining Medications to Enhance Depression Outcomes (CO-MED): Acute and Long-Term Outcomes of a Single-Blind Randomized Study

(2011) A. John Rush et al.   AMERICAN JOURNAL OF PSYCHIATRY

Intravenous Ketamine for Treatment-Resistant Major Depressive Disorder

(2011) Jordan R Covvey et al.   ANNALS OF PHARMACOTHERAPY

Structural Neuroimaging Studies in Major Depressive Disorder

(2011) Matthew J. Kempton   ARCHIVES OF GENERAL PSYCHIATRY

Glutamate N-methyl-D-aspartate Receptor Antagonists Rapidly Reverse Behavioral and Synaptic Deficits Caused by Chronic Stress Exposure

(2011) Nanxin Li et al.   BIOLOGICAL PSYCHIATRY

Characterizing Brain Cortical Plasticity and Network Dynamics Across the Age-Span in Health and Disease with TMS-EEG and TMS-fMRI

(2011) Alvaro Pascual-Leone et al.   BRAIN TOPOGRAPHY

Ketamine as a Novel Antidepressant: From Synapse to Behavior

(2011) J W Murrough   CLINICAL PHARMACOLOGY & THERAPEUTICS

Neuropeptide S alters anxiety, but not depression-like behaviour in Flinders Sensitive Line rats: a genetic animal model of depression

(2011) Gregers Wegener et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

A preliminary naturalistic study of low-dose ketamine for depression and suicide ideation in the emergency department

(2011) Gregory Luke Larkin et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Hippocampal atrophy in first episode depression: A meta-analysis of magnetic resonance imaging studies

(2011) James Cole et al.   JOURNAL OF AFFECTIVE DISORDERS

Signaling pathways underlying the rapid antidepressant actions of ketamine

(2011) Ronald S. Duman et al.   NEUROPHARMACOLOGY

Is neurogenesis relevant in depression and in the mechanism of antidepressant drug action? A critical review

(2011) Siu W. Tang et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

(2010) N. Li et al.   SCIENCE

Structural Plasticity and Hippocampal Function

(2009) Benedetta Leuner et al.   Annual Review of Psychology

Imipramine treatment increases the number of hippocampal synapses and neurons in a genetic animal model of depression

(2009) Fenghua Chen et al.   HIPPOCAMPUS

Enhanced Adult Neurogenesis and Angiogenesis and Altered Affective Behaviors in Mice Overexpressing Vascular Endothelial Growth Factor 120

(2009) H. Udo et al.   JOURNAL OF NEUROSCIENCE

Vascular Endothelial Growth Factor Signaling is Required for the Behavioral Actions of Antidepressant Treatment: Pharmacological and Cellular Characterization

(2009) Joshua Greene et al.   NEUROPSYCHOPHARMACOLOGY

Increased Anterior Cingulate Cortical Activity in Response to Fearful Faces: A Neurophysiological Biomarker that Predicts Rapid Antidepressant Response to Ketamine

(2008) Giacomo Salvadore et al.   BIOLOGICAL PSYCHIATRY

Changes in rat hippocampal CA1 synapses following imipramine treatment

(2008) Fenghua Chen et al.   HIPPOCAMPUS