[Translated article] Tirbanibulin: review of its novel mechanism of action and how it fits into the treatment of actinic keratosis

Phase 3 Trials of Tirbanibulin Ointment for Actinic Keratosis

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465 Tirbanibulin, a novel anti-proliferative and pro-apoptotic agent for the treatment of actinic keratosis

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Actinic keratosis: where do we stand and where is the future going to take us?

(2020) Philipp Cramer et al.   EXPERT OPINION ON EMERGING DRUGS

Reversible binding of the anticancer drug KXO1 (tirbanibulin) to the colchicine-binding site of β-tubulin explains KXO1's low clinical toxicity

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Discovery of Novel Dual Mechanism of Action Src Signaling and Tubulin Polymerization Inhibitors (KX2-391 and KX2-361)

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From actinic keratosis to squamous cell carcinoma: pathophysiology revisited

(2017) M.T. Fernandez Figueras   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Treatment considerations in actinic keratosis

(2017) G. Goldenberg   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Src and SCC: getting to the FAKs

(2015) Stephen A. Ainger et al.   EXPERIMENTAL DERMATOLOGY

Management of actinic keratosis: a practical report and treatment algorithm from AKTeamTMexpert clinicians

(2014) B. Dréno et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Polo-like kinases: structural variations lead to multiple functions

(2014) Sihem Zitouni et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Network meta-analysis of the outcome ‘participant complete clearance’ in nonimmunosuppressed participants of eight interventions for actinic keratosis: a follow-up on a Cochrane review

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Targeting Src and Tubulin in Mucinous Ovarian Carcinoma

(2013) T. Liu et al.   CLINICAL CANCER RESEARCH

Pathobiology of actinic keratosis: Ultraviolet-dependent keratinocyte proliferation

(2012) Brian Berman et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Peptidomimetic Src/Pretubulin Inhibitor KX-01 Alone and in Combination with Paclitaxel Suppresses Growth, Metastasis in Human ER/PR/HER2-Negative Tumor Xenografts

(2012) M. Anbalagan et al.   MOLECULAR CANCER THERAPEUTICS

KX-01, a novel Src kinase inhibitor directed toward the peptide substrate site, synergizes with tamoxifen in estrogen receptor α positive breast cancer

(2011) Muralidharan Anbalagan et al.   BREAST CANCER RESEARCH AND TREATMENT

Microtubule-mediated Src Tyrosine Kinase Trafficking in Neuronal Growth Cones

(2008) Bingbing Wu et al.   MOLECULAR BIOLOGY OF THE CELL