Article
Plant Sciences
Zhen Xu, Rong Ji, Xiangru Zha, Huange Zhao, Songlin Zhou
Summary: This study identified the major constituents of Ageratum conyzoides leaf extract and demonstrated that it inhibited inflammation by suppressing NLRP3 inflammasome activation. The mechanism involved blocking NF-kappa B signaling pathway activation and scavenging intracellular ROS to prevent NLRP3 inflammasome assembly. These findings suggest that Ageratum conyzoides could be a potential traditional herbal medicine for treating NLRP3 inflammasome-driven inflammatory diseases.
JOURNAL OF ETHNOPHARMACOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Jian Wang, Xianfeng Hu, Chenglong Yang, Xiaomao Wu, Rongyu Li, Ming Li
Summary: Plant diseases decrease crop yields and quality, hindering agricultural development. Fungicides are effective in controlling plant diseases by inhibiting fungal chemical synthesis, but the environmental impact of their uncontrolled use has become a major concern. Plant-sourced fungicides have low toxicity, biodegrade easily, do not lead to resistance development, and were found to effectively inhibit bacterial growth on rice sprigs in this study. Gallnut and clove extracts showed strong inhibitory effects on bacteria, with gallnut exhibiting significantly better protection against Rhizoctonia solani in water emulsions compared to clove. This research suggests that plant-sourced fungicides could be a viable alternative to conventional chemical fungicides for treating rice sprig disease.
Article
Nanoscience & Nanotechnology
Zhen Xu, Xiangru Zha, Rong Ji, Huange Zhao, Songlin Zhou
Summary: This study shows that AC-AgNPs, synthesized using Ageratum conyzoids extract, can inhibit the activation of the NLRP3 inflammasome, thereby suppressing the inflammatory response and potentially treating NLRP3 inflammasome-driven inflammatory diseases.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Microbiology
Yinan Wang, Di Yang, Yuhui Bi, Zhiguo Yu
Summary: Four new 20-membered macrolides named venturicidins G-J were isolated from a Streptomyces sp. SN5452 culture, along with two known compounds venturicidins A and B. These compounds showed significant inhibition against the growth and germination of Pyricularia oryzae, suggesting their potential as novel fungicides for controlling rice blast.
Article
Agriculture, Multidisciplinary
Xiao-Fei Shang, Li-Xia Dai, Zhi-Jun Zhang, Cheng-Jie Yang, Sha-Sha Du, Tian-Lin Wu, Ying-Hui He, Jia-Kai Zhu, Ying-Qian Liu, Yin-Fang Yan, Xiao-Lou Miao, Ji-Yu Zhang
Summary: Through proteomics and transcriptomics analysis, this study investigated the potential mode of action of neocryptolepine against Rhizoctonia solani. Results showed that neocryptolepine affected mitochondrial respiratory chain, leading to changes in oxidative phosphorylation and inhibition of complex III activity. The study identified a potential target, cytochrome b-c1 complex subunit Rieske, and demonstrated neocryptolepine's antifungal efficacy and ability to inhibit sclerotia formation in a concentration-dependent manner.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Chemistry, Analytical
Ahmed A. Heflish, Said I. Behiry, Abdulaziz A. Al-Askar, Yiming Su, Ahmed Abdelkhalek, Mohamed K. Gaber
Summary: The study used acetone and hexane extracts of Rhaphiolepis indica fruit to combat two fungal pathogens, Rhizoctonia solani and Fusarium solani, which cause root rot in bean plants. The results showed that both extracts significantly inhibited the growth of the fungi, with the hexane extract showing greater inhibition. The extracts were found to contain phenolic and flavonoid compounds, which may contribute to their antifungal properties.
Article
Agricultural Engineering
Tian-Lin Wu, Bao-Qi Zhang, Xiong-Fei Luo, An-Ping Li, Shao-Yong Zhang, Jun-Xia An, Zhi-Jun Zhang, Ying-Qian Liu
Summary: This study selected 60 essential oils to evaluate their antifungal activity against six plant pathogenic fungi. The results showed that oregano essential oil is an effective natural antifungal product and can inhibit Rhizoctonia solani. Morphological and ultrastructural observations revealed that oregano essential oil damaged the mycelial morphology and cell membrane. Further transcriptomic analysis found that oregano essential oil affected the activity of oxidoreductase, leading to lipid peroxidation and cell death. Additionally, oregano essential oil inhibited the formation of sclerotia of Rhizoctonia solani. This study suggests that essential oils can serve as a new and potential source of natural and eco-friendly antifungal agents.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Agronomy
Yongtian Zhao, Qi Wang, Xia Wu, Mingfang Jiang, Hong Jin, Ke Tao, Taiping Hou
Summary: Eugenol, a main component of Syzygium aromaticum, exhibits antifungal properties by causing morphological changes in Rhizoctonia solani mycelia, downregulating expression of C-4 methyl sterol oxidase, inhibiting ergosterol synthesis, increasing membrane permeability, impairing transportation of amino acids and glucose, as well as affecting oxidative phosphorylation and the tricarboxylic acid cycle. Additionally, eugenol induces oxidative stress by decreasing mitochondrial membrane potential, increasing reactive oxygen species, and malondialdehyde levels, ultimately contributing to its antifungal activity against R. solani.
PEST MANAGEMENT SCIENCE
(2021)
Article
Agricultural Engineering
Lantu Xiong, Xueying Guo, Li Dong, Jintong Jian, Xin Liao, Riyuan Tang, Hanhong Xu
Summary: This study discovered the fungicidal activity of the nonvolatile components of Melaleuca alternifolia against Rhizoctonia solani. Microemulsification significantly improved the efficacy of the nonvolatile components against the pathogen. These findings demonstrate the potential of plant-sourced green formulations for controlling plant pathogens.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Agriculture, Multidisciplinary
Rohit Chhabra, Rajni Sharma, Mandeep Singh Hunjan, Vineet Kumar Sharma, Sapna Thakur, Sanjeev Kumar Chauhan
Summary: The study reveals the antifungal ability of botanical extracts against sheath blight disease in rice. In vitro screening showed that an increase in concentration of botanical extracts led to increased inhibition of mycelial growth of Rhizoctonia solani. Field experiments demonstrated a significant reduction in disease severity when botanical extracts were applied before inoculation. The results suggest that botanical extracts induce early activation of disease resistance and could be an effective tool in sheath blight control.
JOURNAL OF PLANT DISEASES AND PROTECTION
(2023)
Article
Microbiology
Nadia Riera, Danilo Davyt, Rosario Duran, Gregorio Iraola, Philippe Lemanceau, Natalia Bajsa
Summary: Pseudomonas fluorescens CFBP2392 has been found to have antibacterial and antifungal activities, and can effectively inhibit the growth of various plant pathogens and affect the ultrastructure of fungi. Genomic analysis identified multiple biosynthetic gene clusters involved in specialized metabolite production, providing a basis for further exploration of the potential of specialized metabolites in this strain.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Multidisciplinary Sciences
Younes M. Rashad, Mona S. Al Tami, Sara A. Abdalla
Summary: This study discovered an endophytic fungus, A. oryzae YRA3, isolated from a wild plant, which has biocontrol activity against Rhizoctonia root rot in sorghum. The chemical composition analysis revealed the presence of antifungal compounds in its metabolites. Greenhouse experiments showed that inoculating sorghum plants with A. oryzae YRA3 significantly reduced the severity of root rot and promoted plant growth.
SCIENTIFIC REPORTS
(2023)
Article
Agronomy
Gina Erida, Nurdin Saidi, Hasanuddin Hasanuddin, Syafruddin Syafruddin
Summary: This study demonstrates that ethyl acetate leaf extract of Ageratum conyzoides L. at different subfractions and concentrations have significant herbicidal activity against Amaranthus spinosus L., with subfractions A and B at 10% concentration showing the strongest inhibition on weed growth.
Article
Microbiology
Xing-Cheng Zhu, Shu-Gang Xu, Yu-Ru Wang, Meng-Ting Zou, Mohammed Amin Uddin Mridha, Khadija Javed, Yong Wang
Summary: In this study, the bacterial strain Bacillus safensis Y246 isolated from soil exhibited high antifungal activity against Rhizoctonia solani. The volatile organic compounds produced by strain Y246 showed strong inhibitory effects on R. solani mycelial growth. Furthermore, Y246 demonstrated broad-spectrum activity against other pathogens and exhibited excellent antifungal stability under different conditions. These findings provide valuable insights for the development of sustainable agricultural strategies.
Article
Agronomy
M. Siva, S. J. Sreeja, Susha S. Thara, K. N. Anith
Summary: Web blight disease caused by Rhizoctonia solani is a serious problem in cowpea, leading to yield loss. Endophytic bacteria isolated from healthy fodder cowpea and bush cowpea were evaluated for their effects on web blight disease incidence. Bacillus subtilis, B. amyloliquefaciens and B. velezensis were identified as promising biocontrol agents against web blight disease of cowpea caused by R. solani.
Article
Chemistry, Applied
Trong Tuan Nguyen, Thanh Nguyen Quoc Chau, Hieu Mai Van, Toan Phan Quoc, Qui Do Phuoc, The Duy Nguyen, Phuc Dam Nguyen, Tram Nguyen Thi Thu, Tien Dung Le, Trang Dai Thi Xuan, Kamei Kaeko, Kanaori Kenji
Summary: Chemical investigation of the lichen Dirinaria applanata led to the isolation of nine compounds, including a new hopane derivative and six phenolic compounds. Their structures were elucidated by spectroscopic data in combination with published literature.
NATURAL PRODUCT RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Thanh Q. C. Nguyen, Tran Duy Binh, Tuan L. A. Pham, Yen D. H. Nguyen, Dai Thi Xuan Trang, Trong Tuan Nguyen, Kenji Kanaori, Kaeko Kamei
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2020)
Article
Biochemistry & Molecular Biology
Tuan L. A. Pham, Tran Duy Binh, Guanchen Liu, Thanh Q. C. Nguyen, Yen D. H. Nguyen, Ritsuko Sahashi, Tran Thanh Men, Kaeko Kamei
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2020)
Article
Nutrition & Dietetics
Thanh Q. C. Nguyen, Tran Duy Binh, Ryo Kusunoki, Tuan L. A. Pham, Yen D. H. Nguyen, Trong Tuan Nguyen, Kenji Kanaori, Kaeko Kamei
Article
Infectious Diseases
Thefye P. M. Sunthar, Elia Marin, Francesco Boschetto, Matteo Zanocco, Hirofumi Sunahara, Raviduth Ramful, Kaeko Kamei, Wenliang Zhu, Giuseppe Pezzotti
Article
Infectious Diseases
Nguyen Thi Thu Nga, Tran Ngoc Tran, Dominique Holtappels, Nguyen Le Kim Ngan, Nguyen Phuoc Hao, Marta Vallino, Doan Thi Kieu Tien, Nguyen Huan Khanh-Pham, Rob Lavigne, Kaeko Kamei, Jeroen Wagemans, Jeffrey B. Jones
Summary: The study found that using phi 31 alone provides higher disease prevention in greenhouse conditions, while both phage phi 31 alone and the phage cocktail treatments can effectively suppress disease symptoms and increase yield in field conditions.
Article
Agronomy
Cuong C. Nguyen, Thanh Q. C. Nguyen, Kenji Kanaori, Tran Duy Binh, Le Van Vang, Kaeko Kamei
Summary: Compounds derived from Praxelis clematidea showed antimicrobial effects on Xanthomonas oryzae and Pyricularia oryzae, with specific compounds identified and isolated for their antibacterial and antifungal activities, which could be further validated in field trials.
Article
Infectious Diseases
Raviduth Ramful, Thefye P. M. Sunthar, Kaeko Kamei, Giuseppe Pezzotti
Summary: The antibacterial characteristics of different types of Japanese bamboo were investigated, and the influence of extraction methods on the effectiveness of antibacterial agents was studied. The results showed that antibacterial agents derived from the non-extraction method had better efficacy against E. coli and S. aureus, especially those derived from thermally modified bamboo powder. FTIR analysis identified the C-O and C-H functional groups in lignin as responsible for the antibacterial trait observed in bamboo.
Article
Microbiology
Vo Thi Tu Anh, Nguyen Huan Pham-Khanh, Nguyen Song Han, Hirofumi Sunahara, Kaeko Kamei
Summary: In this study, a Vibrio phage KIT05 was isolated from a shrimp farm in Vietnam and characterized based on its morphology, growth curve, lytic properties, and genome sequence. KIT05 belongs to the family Podoviridae and does not contain any virulent or lysogenic genes. This study may contribute to the identification of a potential biocontrol agent for Vibrio parahaemolyticus.
CURRENT MICROBIOLOGY
(2022)
Article
Virology
Anh Vo Thi Tu, Nguyen Huan Pham-Khanh, Song Han Nguyen, Hirofumi Sunahara, Trang Dai Thi Xuan, Kaeko Kamei
Summary: Vibrio phage KIT04, isolated from muscle tissue samples in a local market in Vietnam, is a lytic phage that specifically targets Vibrio parahaemolyticus. It significantly reduces V. parahaemolyticus in vitro and has a unique genome and hypothetical proteins, making it a novel phage candidate for controlling Vibrio pathogens.
Article
Agriculture, Dairy & Animal Science
N. T. Ngu, L. N. N. Phuong, L. H. Anh, H. T. Loc, N. T. Tam, P. K. N. Huan, T. H. Diep, K. Kamei
Summary: This study evaluated the efficacy of bacteriophages on Salmonella-infected native Vietnamese broiler breed. The results showed that bacteriophage administration led to increased weight gain and improved feed conversion ratio. However, some issues caused by the infection were not completely resolved by the bacteriophage treatment.
BRAZILIAN JOURNAL OF POULTRY SCIENCE
(2022)
Article
Integrative & Complementary Medicine
Patlada Suthamwong, Manabu Minami, Toshiaki Okada, Nonomi Shiwaku, Mai Uesugi, Masayuki Yokode, Kaeko Kamei
BMC COMPLEMENTARY MEDICINE AND THERAPIES
(2020)
