Serum Cytokine Profile, Beta-Hexosaminidase A Enzymatic Activity and GM2 Ganglioside Levels in the Plasma of a Tay-Sachs Disease Patient after Cord Blood Cell Transplantation and Curcumin Administration: A Case Report

Functionality of a bicistronic construction containing HEXA and HEXB genes encoding β-hexosaminidase A for cell-mediated therapy of GM2 gangliosidoses

(2021) AlbertA Rizvanov et al.   Neural Regeneration Research

Autophagy in Neurodegenerative Diseases: A Hunter for Aggregates

(2020) Hyungsun Park et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Curcumin Analogue C1 Promotes Hex and Gal Recruitment to the Plasma Membrane via mTORC1-Independent TFEB Activation

(2019) Alessandro Magini et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Safety and efficacy of curcumin versus diclofenac in knee osteoarthritis: a randomized open-label parallel-arm study

(2019) Dhaneshwar Shep et al.   Trials

Interferon downstream signaling is activated early in pre-symptomatic Niemann-Pick disease type C

(2019) Samuel D. Shin et al.   NEUROSCIENCE LETTERS

Immunomodulatory and Anti-Inflammatory Potential of Curcumin for the Treatment of Allergic Asthma: Effects on Expression Levels of Pro-inflammatory Cytokines and Aquaporins

(2019) Hira Shahid et al.   INFLAMMATION

Loss of amyloid precursor protein exacerbates early inflammation in Niemann-Pick disease type C

(2019) Samuel D. Shin et al.   Journal of Neuroinflammation

Memory and Brain Amyloid and Tau Effects of a Bioavailable Form of Curcumin in Non-Demented Adults: A Double-Blind, Placebo-Controlled 18-Month Trial

(2018) Gary W. Small et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

Could enzyme replacement therapy promote immune tolerance in Gaucher disease type 1?

(2018) Marina Cadena Matta et al.   BLOOD CELLS MOLECULES AND DISEASES

Safety and Efficacy of Nanocurcumin as Add-On Therapy to Riluzole in Patients With Amyotrophic Lateral Sclerosis: A Pilot Randomized Clinical Trial

(2018) Mona Ahmadi et al.   Neurotherapeutics

Amyotrophic Lateral Sclerosis and Oxidative Stress: a Double-Blind Therapeutic Trial After Curcumin Supplementation

(2018) Lucia Chico et al.   CNS & Neurological Disorders-Drug Targets

Efficacy and mechanisms underlying the effects of allogeneic umbilical cord mesenchymal stem cell transplantation on acute radiation injury in tree shrews

(2018) De-Bin Guo et al.   CYTOTECHNOLOGY

IP-10 is highly involved in HIV infection

(2018) Jie Lei et al.   CYTOKINE

Potential role of CSF cytokine profiles in discriminating infectious from non-infectious CNS disorders

(2018) Danielle Fortuna et al.   PLoS One

New Approaches to Tay-Sachs Disease Therapy

(2018) Valeriya V. Solovyeva et al.   Frontiers in Physiology

Analysis of different innovative formulations of curcumin for improved relative oral bioavailability in human subjects

(2017) Martin Purpura et al.   EUROPEAN JOURNAL OF NUTRITION

1α,25-dihydroxyvitamin D3 Interacts with Curcuminoids to Stimulate Amyloid-β Clearance by Macrophages of Alzheimer's Disease Patients

(2017) Ava Masoumi et al.   JOURNAL OF ALZHEIMERS DISEASE

Clinical and laboratory outcomes after umbilical cord blood transplantation in a patient with mucolipidosis II alpha/beta

(2016) Takumi Shibazaki et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Intranasal Curcumin Inhibits Pulmonary Fibrosis by Modulating Matrix Metalloproteinase-9 (MMP-9) in Ovalbumin-Induced Chronic Asthma

(2016) Preeti S. Chauhan et al.   INFLAMMATION

Gray matter regions statistically mediating the cross-sectional association of eotaxin and set-shifting among older adults with major depressive disorder

(2016) Stephen F. Smagula et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Immunological biomarkers associated with brain structure and executive function in late-life depression: exploratory pilot study

(2016) Stephen F. Smagula et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Neutralization of RANTES and Eotaxin Prevents the Loss of Dopaminergic Neurons in a Mouse Model of Parkinson Disease

(2016) Goutam Chandra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tay–Sachs disease mutations in HEXA target the α chain of hexosaminidase A to endoplasmic reticulum–associated degradation

(2016) Devin Dersh et al.   MOLECULAR BIOLOGY OF THE CELL

Cerebral Spinal Fluid levels of Cytokines are elevated in Patients with Metachromatic Leukodystrophy

(2016) Kathryn A. Thibert et al.   Scientific Reports

Elevated cerebral spinal fluid biomarkers in children with mucopolysaccharidosis I-H

(2016) Gerald V. Raymond et al.   Scientific Reports

Increase of a group of PTC+ transcripts by curcumin through inhibition of the NMD pathway

(2015) Dairong Feng et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Symptomatic Improvement, Increased Life-Span and Sustained Cell Homing in Amyotrophic Lateral Sclerosis After Transplantation of Human Umbilical Cord Blood Cells Genetically Modified with Adeno-Viral Vectors Expressing a Neuro-Protective Factor and a Neural Cell Adhesion Molecule

(2015) Rustem Islamov et al.   CURRENT GENE THERAPY

Cord blood is the optimal graft source for the treatment of pediatric patients with lysosomal storage diseases: clinical outcomes and future directions

(2015) Mieke Aldenhoven et al.   CYTOTHERAPY

Clinical development of curcumin in neurodegenerative disease

(2015) Shuxin Hu et al.   Expert Review of Neurotherapeutics

Biomarkers of central nervous system inflammation in infantile and juvenile gangliosidoses

(2015) Jeanine R. Jarnes Utz et al.   MOLECULAR GENETICS AND METABOLISM

Clinical development of curcumin in neurodegenerative disease

(2015) Shuxin Hu et al.   Expert Review of Neurotherapeutics

The Anti-Inflammatory Activity of Curcumin Protects the Genital Mucosal Epithelial Barrier from Disruption and Blocks Replication of HIV-1 and HSV-2

(2015) Victor H. Ferreira et al.   PLoS One

Liquid chromatography/electrospray ionisation–tandem mass spectrometry quantification of GM2 gangliosides in human peripheral cells and plasma

(2014) Maria Fuller et al.   ANALYTICAL BIOCHEMISTRY

A new liquid chromatography/tandem mass spectrometry method for quantification of gangliosides in human plasma

(2014) Qianyang Huang et al.   ANALYTICAL BIOCHEMISTRY

A high-throughput quantification method of curcuminoids and curcumin metabolites in human plasma via high-performance liquid chromatography/tandem mass spectrometry

(2014) Yu Cao et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Investigation of the effects of solid lipid curcumin on cognition and mood in a healthy older population

(2014) Katherine HM Cox et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Macrophage-Derived Chemokine (CCL22) Is a Novel Mediator of Lung Inflammation Following Hemorrhage and Resuscitation

(2014) Jillian R. Richter et al.   SHOCK

Curcumin and neurodegenerative diseases

(2013) Adriana Monroy et al.   BIOFACTORS

Neurodevelopmental Outcomes of Umbilical Cord Blood Transplantation in Metachromatic Leukodystrophy

(2013) Holly R. Martin et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Analysis of the Efficiency of Gene-Cell Therapy in Transgenic Mice with Amyotrophic Lateral Sclerosis Phenotype

(2013) M. A. Mukhamedyarov et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

A phase I study investigating the safety and pharmacokinetics of highly bioavailable curcumin (Theracurmin®) in cancer patients

(2013) Masashi Kanai et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Vascular Endothelial Growth Factor (VEGF-a) in Fabry disease: Association with cutaneous and systemic manifestations with vascular involvement

(2013) Anna Zampetti et al.   CYTOKINE

Rapid and sensitive LC-ESI-MS of gangliosides

(2013) Aldo D. Garcia et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Impact of the CD40-CD40L Dyad in Alzheimers Disease

(2012) Brian Giunta et al.   CNS & Neurological Disorders-Drug Targets

Inflammatory cell trafficking across the blood-brain barrier: chemokine regulation and in vitro models

(2012) Yukio Takeshita et al.   IMMUNOLOGICAL REVIEWS

Possible role of transforming growth factor-β1 and vascular endothelial growth factor in Fabry disease nephropathy

(2012) MI HEE LEE et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Diverse effects of a low dose supplement of lipidated curcumin in healthy middle aged people

(2012) Robert A DiSilvestro et al.   Nutrition Journal

Relative Levels of the Inflammatory Cytokine TNFα and the Soluble CD40 Ligand Profile in Serum Correlate with the Thyrotoxic Activity of Graves' Disease

(2012) Keiko Yamamoto et al.   THYROID

Dose-escalation and pharmacokinetic study of nanoparticle curcumin, a potential anticancer agent with improved bioavailability, in healthy human volunteers

(2011) Masashi Kanai et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Successful cord blood transplantation in a 42-day-old boy with infantile Krabbe disease

(2011) Hiroshi Yagasaki et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

The ageing systemic milieu negatively regulates neurogenesis and cognitive function

(2011) Saul A. Villeda et al.   NATURE

Potential biomarkers of osteonecrosis in Gaucher disease

(2010) Elena V. Pavlova et al.   BLOOD CELLS MOLECULES AND DISEASES

Safety and Pharmacokinetics of a Solid Lipid Curcumin Particle Formulation in Osteosarcoma Patients and Healthy Volunteers

(2010) Vikram S. Gota et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The Effect of Epidermal Growth Factor in the Injured Brain after Trauma in Rats

(2010) Dong Sun et al.   JOURNAL OF NEUROTRAUMA

Intracranial Calcification after Cord Blood Neonatal Transplantation for Krabbe Disease

(2010) A. Lehman et al.   NEUROPEDIATRICS

Characterization of Gaucher disease bone marrow mesenchymal stromal cells reveals an altered inflammatory secretome

(2009) P. M. Campeau et al.   BLOOD

Unilaterally and rapidly progressing white matter lesion and elevated cytokines in a patient with Tay–Sachs disease

(2009) Tomomi Hayase et al.   BRAIN & DEVELOPMENT

Effect of Oral Curcumin on Déjérine-Sottas Disease

(2009) Joshua Burns et al.   PEDIATRIC NEUROLOGY

Umbilical cord blood transplantation for juvenile metachromatic leukodystrophy

(2008) Tyler Mark Pierson et al.   ANNALS OF NEUROLOGY

Unrelated donor umbilical cord blood transplantation for inherited metabolic disorders in 159 pediatric patients from a single center: influence of cellular composition of the graft on transplantation outcomes

(2008) V. K. Prasad et al.   BLOOD

Pharmacokinetics of Curcumin Conjugate Metabolites in Healthy Human Subjects

(2008) S. K. Vareed et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Simultaneous quantification of GM1 and GM2 gangliosides by isotope dilution tandem mass spectrometry

(2008) Jianghong Gu et al.   CLINICAL BIOCHEMISTRY

Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases

(2008) Bharat B. Aggarwal et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The Epidermal Growth Factor Receptor System in Skin Repair and Inflammation

(2007) Saveria Pastore et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY