Update and Evaluation of a High-Throughput In Vitro Mass Balance Distribution Model: IV-MBM EQP v2.0

Effective exposure of chemicals in in vitro cell systems: A review of chemical distribution models

(2021) Susana Proença et al.   TOXICOLOGY IN VITRO

Predicting exposure concentrations of chemicals with a wide range of volatility and hydrophobicity in different multi-well plate set-ups

(2021) Julita Stadnicka-Michalak et al.   Scientific Reports

Experimental Exposure Assessment of Ionizable Organic Chemicals in In Vitro Cell-Based Bioassays

(2020) Julia Huchthausen et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Demonstrating the need for chemical exposure characterisation in a microplate test system: toxicity screening of sixteen pesticides on two marine microalgae

(2019) Valentin Dupraz et al.   CHEMOSPHERE

Quantification of freely dissolved effect concentrations in in vitro cell-based bioassays

(2019) Luise Henneberger et al.   ARCHIVES OF TOXICOLOGY

Combined Ion-Trapping and Mass Balance Models To Describe the pH-Dependent Uptake and Toxicity of Acidic and Basic Pharmaceuticals in Zebrafish Embryos (Danio rerio)

(2019) Lisa Bittner et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

How To Improve the Dosing of Chemicals in High-Throughput in Vitro Mammalian Cell Assays

(2019) Fabian C. Fischer et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Baseline Toxicity and Volatility Cutoff in Reporter Gene Assays Used for High-Throughput Screening

(2019) Beate I. Escher et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Experimental Validation of Mass Balance Models for in Vitro Cell-Based Bioassays

(2019) Luise Henneberger et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Evaluation and Optimization of Pharmacokinetic Models for in Vitro to in Vivo Extrapolation of Estrogenic Activity for Environmental Chemicals

(2018) Warren M. Casey et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

C18-Coated Solid-Phase Microextraction Fibers for the Quantification of Partitioning of Organic Acids to Proteins, Lipids, and Cells

(2018) Luise Henneberger et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Application of Experimental Polystyrene Partition Constants and Diffusion Coefficients to Predict the Sorption of Neutral Organic Chemicals to Multiwell Plates in in Vivo and in Vitro Bioassays

(2018) Fabian C. Fischer et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

VIVD: Virtual in vitro distribution model for the mechanistic prediction of intracellular concentrations of chemicals in in vitro toxicity assays

(2018) C. Fisher et al.   TOXICOLOGY IN VITRO

Practical use of the Virtual Cell Based Assay: Simulation of repeated exposure experiments in liver cell lines

(2017) A. Paini et al.   TOXICOLOGY IN VITRO

Theoretical and mathematical foundation of the Virtual Cell Based Assay – A review

(2017) J.M. Zaldívar Comenges et al.   TOXICOLOGY IN VITRO

The virtual cell based assay: Current status and future perspectives

(2017) Rabea Graepel et al.   TOXICOLOGY IN VITRO

Development of a general baseline toxicity QSAR model for the fish embryo acute toxicity test

(2016) Nils Klüver et al.   CHEMOSPHERE

Equilibrium Sorption of Structurally Diverse Organic Ions to Bovine Serum Albumin

(2016) Luise Henneberger et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Analysis of the Effects of Cell Stress and Cytotoxicity onIn VitroAssay Activity Across a Diverse Chemical and Assay Space

(2016) Richard Judson et al.   TOXICOLOGICAL SCIENCES

Application of Mass Balance Models and the Chemical Activity Concept To Facilitate the Use of in Vitro Toxicity Data for Risk Assessment

(2014) James M. Armitage et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Measured and Modeled Toxicokinetics in Cultured Fish Cells and Application to In Vitro - In Vivo Toxicity Extrapolation

(2014) Julita Stadnicka-Michalak et al.   PLoS One

General Model for Estimating Partition Coefficients to Organisms and Their Tissues Using the Biological Compositions and Polyparameter Linear Free Energy Relationships

(2013) Satoshi Endo et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Characterization of primary human hepatocytes, HepG2 cells, and HepaRG cells at the mRNA level and CYP activity in response to inducers and their predictivity for the detection of human hepatotoxins

(2012) H. H. J. Gerets et al.   CELL BIOLOGY AND TOXICOLOGY

Predicting Fish Acute Toxicity Using a Fish Gill Cell Line-Based Toxicity Assay

(2012) Katrin Tanneberger et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Serum Albumin Binding of Structurally Diverse Neutral Organic Compounds: Data and Models

(2011) Satoshi Endo et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Capacities of Membrane Lipids to Accumulate Neutral Organic Chemicals

(2011) Satoshi Endo et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Integration of Dosimetry, Exposure, and High-Throughput Screening Data in Chemical Toxicity Assessment

(2011) Barbara A. Wetmore et al.   TOXICOLOGICAL SCIENCES

Effects of Solvents and Dosing Procedure on Chemical Toxicity in Cell-Basedin VitroAssays

(2010) Katrin Tanneberger et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Solubility enhancement of hydrophobic compounds by cosolvents: Role of solute hydrophobicity on the solubilization effect

(2010) Yasuhiro Miyako et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

In Vitro Screening of Environmental Chemicals for Targeted Testing Prioritization: The ToxCast Project

(2009) Richard S. Judson et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

HOW TO DEAL WITH LIPOPHILIC AND VOLATILE ORGANIC SUBSTANCES IN MICROTITER PLATE ASSAYS

(2008) René Schreiber et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

General approach for the calculation of tissue to plasma partition coefficients

(2007) Walter Schmitt   TOXICOLOGY IN VITRO