Mitochondrial Electron Transport Chain Protein Abnormalities Detected in Plasma Extracellular Vesicles in Alzheimer’s Disease

Neural cell‐derived plasma exosome protein abnormalities implicate mitochondrial impairment in first episodes of psychosis

(2021) Edward J. Goetzl et al.   FASEB JOURNAL

Mitovesicles are a novel population of extracellular vesicles of mitochondrial origin altered in Down syndrome

(2021) Pasquale D’Acunzo et al.   Science Advances

Whole‐genome sequencing reveals new Alzheimer's disease–associated rare variants in loci related to synaptic function and neuronal development

(2021) Dmitry Prokopenko et al.   Alzheimers & Dementia

Interneuronal exchange and functional integration of synaptobrevin via extracellular vesicles

(2021) A. Alejandro Vilcaes et al.   NEURON

α-Synuclein pathology in Parkinson disease activates homeostatic NRF2 anti-oxidant response

(2021) Alberto Delaidelli et al.   Acta Neuropathologica Communications

Interplay Between Mitochondrial Oxidative Disorders and Proteostasis in Alzheimer’s Disease

(2020) Emilio Llanos-González et al.   Frontiers in Neuroscience

Interference With Complex IV as a Model of Age-Related Decline in Synaptic Connectivity

(2020) Martin Kriebel et al.   Frontiers in Molecular Neuroscience

Extracellular vesicle biomarkers of Alzheimer's disease associated with sub‐clinical cognitive decline in late middle age

(2020) Erden Eren et al.   Alzheimers & Dementia

Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing

(2020) Stephen C. Cunnane et al.   NATURE REVIEWS DRUG DISCOVERY

Neuronal insulin signaling and brain structure in non-demented older adults: The ARIC Study

(2020) Keenan A. Walker et al.   NEUROBIOLOGY OF AGING

Mitochondrial Protrusions in Neuronal Cells

(2020) Pamela J. Yao et al.   iScience

Mitochondrial RNA in Alzheimer’s Disease Circulating Extracellular Vesicles

(2020) Kyoung Mi Kim et al.   Frontiers in Cell and Developmental Biology

Quantitative profiling brain proteomes revealed mitochondrial dysfunction in Alzheimer’s disease

(2019) Sunil S Adav et al.   Molecular Brain

Association of Extracellular Vesicle Biomarkers With Alzheimer Disease in the Baltimore Longitudinal Study of Aging

(2019) Dimitrios Kapogiannis et al.   JAMA Neurology

Oxidative stress in the aging substantia nigra and the etiology of Parkinson's disease

(2019) Benjamin G. Trist et al.   AGING CELL

Perspectives on Oxidative Stress in Alzheimer’s Disease and Predictions of Future Research Emphases

(2018) D. Allan Butterfield   JOURNAL OF ALZHEIMERS DISEASE

Mitochondria and Mitochondrial Cascades in Alzheimer’s Disease

(2018) Russell H. Swerdlow   JOURNAL OF ALZHEIMERS DISEASE

Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders

(2018) Melanie D. Sweeney et al.   Nature Reviews Neurology

Reduced expression of SIRT1 and SOD-1 and the correlation between these levels in various regions of the brains of patients with Alzheimer’s disease

(2018) Kun Cao et al.   JOURNAL OF CLINICAL PATHOLOGY

Evidence supporting oxidative stress in a moderately affected area of the brain in Alzheimer’s disease

(2018) Priscilla Youssef et al.   Scientific Reports

Plasma Extracellular Vesicles Enriched for Neuronal Origin: A Potential Window into Brain Pathologic Processes

(2017) Maja Mustapic et al.   Frontiers in Neuroscience

Decreased synaptic proteins in neuronal exosomes of frontotemporal dementia and Alzheimer’s disease

(2016) Edward J. Goetzl et al.   FASEB JOURNAL

Mitochondrial superoxide: a key player in Alzheimer's disease

(2016) Cynthia A. Massaad et al.   Aging-US

Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: A case-control study

(2015) Massimo S. Fiandaca et al.   Alzheimers & Dementia

Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer's disease

(2015) Sandra I. Mota et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Extracellular ATP modulates synaptic plasticity induced by activation of metabotropic glutamate receptors in the hippocampus

(2015) Yoshihiko YAMAZAKI et al.   BIOMEDICAL RESEARCH-TOKYO

Dysfunctionally phosphorylated type 1 insulin receptor substrate in neural-derived blood exosomes of preclinical Alzheimer’s disease

(2015) Dimitrios Kapogiannis et al.   FASEB JOURNAL

Oxidative stress and mitochondrial dysfunction in Alzheimer's disease

(2013) Xinglong Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mitochondrion-Derived Reactive Oxygen Species Lead to Enhanced Amyloid Beta Formation

(2012) Kristina Leuner et al.   ANTIOXIDANTS & REDOX SIGNALING

Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage

(2012) M. Manczak et al.   HUMAN MOLECULAR GENETICS

Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Reisa A. Sperling et al.   Alzheimers & Dementia

Tau Accumulation Causes Mitochondrial Distribution Deficits in Neurons in a Mouse Model of Tauopathy and in Human Alzheimer's Disease Brain

(2011) Katherine J. Kopeikina et al.   AMERICAN JOURNAL OF PATHOLOGY

SOD1 (Copper/Zinc Superoxide Dismutase) Deficiency Drives Amyloid β Protein Oligomerization and Memory Loss in Mouse Model of Alzheimer Disease

(2011) Kazuma Murakami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects

(2009) Leslie M. Shaw et al.   ANNALS OF NEUROLOGY

Intracellular amyloid beta interacts with SOD1 and impairs the enzymatic activity of SOD1: implications for the pathogenesis of amyotrophic lateral sclerosis

(2009) Eun Jin Yoon et al.   EXPERIMENTAL AND MOLECULAR MEDICINE