Gasdermin D in Different Subcellular Locations Predicts Diverse Progression, Immune Microenvironment and Prognosis in Colorectal Cancer

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2021) Hyuna Sung et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Diagnosis and Treatment of Metastatic Colorectal Cancer

(2021) Leah H. Biller et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Gasdermin D pore structure reveals preferential release of mature interleukin-1

(2021) Shiyu Xia et al.   NATURE

Role of pyroptosis in cancer cells and clinical applications

(2021) Xiaoli Ju et al.   BIOCHIMIE

Perspectives on Immunotherapy of Metastatic Colorectal Cancer

(2021) Yongjiu Dai et al.   Frontiers in Oncology

Significance of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, lymphocyte-to-monocyte ratio and prognostic nutritional index for predicting clinical outcomes in T1–2 rectal cancer

(2020) Li-jian Xia et al.   BMC CANCER

Intratumor Heterogeneity: The Rosetta Stone of Therapy Resistance

(2020) Andriy Marusyk et al.   CANCER CELL

Mechanism and regulation of pyroptosis-mediated in cancer cell death

(2020) Jianwei Ruan et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Signification of Systemic Immune-Inflammation Index for prediction of prognosis after resecting in patients with colorectal cancer

(2020) Saori Yatabe et al.   INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

LPS Enhances the Chemosensitivity of Oxaliplatin in HT29 Cells via GSDMD-Mediated Pyroptosis

(2020) Li-Sha Wu et al.   Cancer Management and Research

The role of pyroptosis in gastrointestinal cancer and immune responses to intestinal microbial infection

(2019) Cheng-Bei Zhou et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

The role of pyroptosis in cancer: pro-cancer or pro-“host”?

(2019) Xiaojing Xia et al.   Cell Death & Disease

The Diversification of Cell Death and Immunity: Memento Mori

(2019) Arnaud J. Legrand et al.   MOLECULAR CELL

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

(2018) Lorenzo Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Downregulation of gasdermin D promotes gastric cancer proliferation by regulating cell cycle-related proteins

(2018) Wei Jie Wang et al.   Journal of Digestive Diseases

ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation

(2018) Sebastian Rühl et al.   SCIENCE

Shiga Toxin/Lipopolysaccharide Activates Caspase-4 and Gasdermin D to Trigger Mitochondrial Reactive Oxygen Species Upstream of the NLRP3 Inflammasome

(2018) Jaye M. Platnich et al.   Cell Reports

Interleukin-18: Biological properties and role in disease pathogenesis

(2017) Gilles Kaplanski   IMMUNOLOGICAL REVIEWS

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

(2017) Yupeng Wang et al.   NATURE

Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death

(2017) Jianjin Shi et al.   TRENDS IN BIOCHEMICAL SCIENCES

Inflammation-Dependent IL18 Signaling Restricts Hepatocellular Carcinoma Growth by Enhancing the Accumulation and Activity of Tumor-Infiltrating Lymphocytes

(2016) Geoffrey J. Markowitz et al.   CANCER RESEARCH

Key Role of DAMP in Inflammation, Cancer, and Tissue Repair

(2016) Franco Pandolfi et al.   CLINICAL THERAPEUTICS

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

Prognostic clinical factors in pretreated colorectal cancer patients receiving regorafenib: implications for clinical management.

(2015) Michela Del Prete et al.   Oncotarget

Inflammatory caspases are innate immune receptors for intracellular LPS

(2014) Jianjin Shi et al.   NATURE

The preoperative lymphocyte to monocyte ratio predicts clinical outcome in patients with stage III colon cancer

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Immunity, Inflammation, and Cancer

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