Harnessing the ambiphilicity of silyl nitronates in a catalytic asymmetric approach to aliphatic β3-amino acids

Confinement as a Unifying Element in Selective Catalysis

(2020) Benjamin Mitschke et al.   Chem

A multi-substrate screening approach for the identification of a broadly applicable Diels–Alder catalyst

(2019) Hyejin Kim et al.   Nature Communications

IDPi Catalysis

(2019) Benjamin List et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Unanticipated Silyl Transfer in Enantioselective α,β-Unsaturated Acyl Ammonium Catalysis Using Silyl Nitronates

(2019) Anastassia Matviitsuk et al.   ORGANIC LETTERS

The Catalytic Asymmetric Mukaiyama-Michael Reaction of Silyl Ketene Acetals with α,β-Unsaturated Methyl Esters

(2018) Tim Gatzenmeier et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Approaching sub-ppm-level asymmetric organocatalysis of a highly challenging and scalable carbon–carbon bond forming reaction

(2018) Han Yong Bae et al.   Nature Chemistry

Scalable and Highly Diastereo- and Enantioselective Catalytic Diels–Alder Reaction of α,β-Unsaturated Methyl Esters

(2018) Tim Gatzenmeier et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Confined acids catalyze asymmetric single aldolizations of acetaldehyde enolates

(2018) Lucas Schreyer et al.   SCIENCE

Extremely Active Organocatalysts Enable a Highly Enantioselective Addition of Allyltrimethylsilane to Aldehydes

(2016) Philip S. J. Kaib et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Lewis acid organocatalysis of the Diels-Alder reaction by a silylated C-H acid

(2016) T. Gatzenmeier et al.   SCIENCE

ButMe2SiOTf-promoted cyanosilylation of six-membered cyclic nitronates with trialkylsilyl cyanides or tert-butyl isocyanide1

(2014) Andrey A. Mikhaylov et al.   MENDELEEV COMMUNICATIONS

Stereoselective Amine Addition to Six-Membered Cyclic Nitronates Promoted by Silyl Triflate

(2013) Andrey A. Mikhaylov et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

C-C Coupling of Acyclic Nitronates with Silyl Ketene Acetals under Silyl Triflate Catalysis: Reactivity Umpolung of Aliphatic Nitro Compounds

(2012) Vladimir O. Smirnov et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

3-Halomethylated cyclic nitronates: synthesis and nucleophilic substitution

(2011) Andrey A. Mikhaylov et al.   TETRAHEDRON

Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture

(2010) C. K. Savile et al.   SCIENCE

Five-Membered Cyclic Nitronates in C-C Coupling with 1-(tert-Butyldimethylsilyloxy)-1-methoxyethylene

(2009) Vladimir O. Smirnov et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Aldehyde α-Nitroalkylation via Oxidative Organocatalysis

(2009) Jonathan E. Wilson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Efficient Asymmetric Synthesis of Sitagliptin

(2009) Karl B. Hansen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY