Novel Phage Lysin Abp013 against Acinetobacter baumannii

A VersaTile-driven platform for rapid hit-to-lead development of engineered lysins

(2020) H. Gerstmans et al.   Science Advances

The endolysin of the Acinetobacter baumannii phage vB_AbaP_D2 shows broad antibacterial activity

(2020) Yuyu Yuan et al.   Microbial Biotechnology

Resistance to peptidoglycan-degrading enzymes

(2020) Alexander V. Grishin et al.   CRITICAL REVIEWS IN MICROBIOLOGY

SMART: recent updates, new developments and status in 2020

(2020) Ivica Letunic et al.   NUCLEIC ACIDS RESEARCH

Characterization of a Lytic Bacteriophage vB_EfaS_PHB08 Harboring Endolysin Lys08 against Enterococcus faecalis Biofilms

(2020) Dan Yang et al.   Microorganisms

LysSAP26, a New Recombinant Phage Endolysin with a Broad Spectrum Antibacterial Activity

(2020) Shukho Kim et al.   Viruses-Basel

Engineered Lysins With Customized Lytic Activities Against Enterococci and Staphylococci

(2020) Hana Sakina Binte Muhammad Jai et al.   Frontiers in Microbiology

A Novel Phage PD-6A3, and Its Endolysin Ply6A3, With Extended Lytic Activity Against Acinetobacter baumannii

(2019) Minle Wu et al.   Frontiers in Microbiology

Characterization and genome annotation of a newly detected bacteriophage infecting multidrug-resistant Acinetobacter baumannii

(2019) Zichen Yang et al.   ARCHIVES OF VIROLOGY

Isolation of phage lysins that effectively kill Pseudomonas aeruginosa in mouse models of lung and skin infection

(2019) Assaf Raz et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Economic burden of antibiotic resistance in ESKAPE organisms: a systematic review

(2019) Xuemei Zhen et al.   Antimicrobial Resistance and Infection Control

CDD/SPARCLE: the conserved domain database in 2020

(2019) Shennan Lu et al.   NUCLEIC ACIDS RESEARCH

Molecular characterization of the outer membrane of Pseudomonas aeruginosa

(2019) Cesar A. López et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Phage-derived lysins as potential agents for eradicating biofilms and persisters

(2018) Umender Sharma et al.   DRUG DISCOVERY TODAY

Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis

(2018) Evelina Tacconelli et al.   LANCET INFECTIOUS DISEASES

In vitro characterization of PlyE146, a novel phage lysin that targets Gram-negative bacteria

(2018) Yu Larpin et al.   PLoS One

Estimates of the global, regional, and national morbidity, mortality, and aetiologies of lower respiratory infections in 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

(2018) Christopher Troeger et al.   LANCET INFECTIOUS DISEASES

Antimicrobial resistance in healthcare, agriculture and the environment: the biochemistry behind the headlines

(2017) Henrietta Venter et al.   Essays in Biochemistry

Modular endolysin of Burkholderia AP3 phage has the largest lysozyme-like catalytic subunit discovered to date and no catalytic aspartate residue

(2017) Barbara Maciejewska et al.   Scientific Reports

A bacteriophage endolysin that eliminates intracellular streptococci

(2016) Yang Shen et al.   eLife

Novel Phage Lysin Capable of Killing the Multidrug-Resistant Gram-Negative Bacterium Acinetobacter baumannii in a Mouse Bacteremia Model

(2015) Rolf Lood et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antimicrobial resistance in humans, livestock and the wider environment

(2015) M. Woolhouse et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Major biologic characteristics of Acinetobacter baumannii isolates from hospital environmental and patients' respiratory tract sources

(2014) Nathir Obeidat et al.   AMERICAN JOURNAL OF INFECTION CONTROL

A Highly Active and Negatively Charged Streptococcus pyogenes Lysin with a Rare d-Alanyl-l-Alanine Endopeptidase Activity Protects Mice against Streptococcal Bacteremia

(2014) Rolf Lood et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antibacterial properties of Acinetobacter baumanniiphage Abp1 endolysin (PlyAB1)

(2014) Guangtao Huang et al.   BMC INFECTIOUS DISEASES

Engineered Endolysin-Based "Artilysins" To Combat Multidrug-Resistant Gram-Negative Pathogens

(2014) Y. Briers et al.   mBio

In VitroCharacterization of PlySK1249, a Novel Phage Lysin, and Assessment of Its Antibacterial Activity in a Mouse Model of Streptococcus agalactiae Bacteremia

(2013) Frank Oechslin et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antibacterial activity of Acinetobacter baumannii phage ϕAB2 endolysin (LysAB2) against both Gram-positive and Gram-negative bacteria

(2011) Meng-Jiun Lai et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance

(2011) A.-P. Magiorakos et al.   CLINICAL MICROBIOLOGY AND INFECTION

Increased Antibiotic Resistance of Escherichia coli in Mature Biofilms

(2009) A. Ito et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY