Pseudomonas aeruginosa mexR and mexEF Antibiotic Efflux Pump Variants Exhibit Increased Virulence

Pseudomonas aeruginosa Susceptibility Patterns and Associated Clinical Outcomes in People with Cystic Fibrosis following Approval of Aztreonam Lysine for Inhalation

(2020) Claire L Keating et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Genomic analysis identifies novel Pseudomonas aeruginosa resistance genes under selection during inhaled aztreonam therapy in vivo

(2019) Kathryn McLean et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Selection for increased quorum-sensing cooperation in Pseudomonas aeruginosa through the shut-down of a drug resistance pump

(2018) Ron D. Oshri et al.   ISME Journal

Mutational analyses of regulatory genes, mexR, nalC, nalD and mexZ of mexAB-oprM and mexXY operons, in efflux pump hyperexpressing multidrug-resistant clinical isolates of Pseudomonas aeruginosa

(2018) Manju Suresh et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Epidemiology, Biology, and Impact of Clonal Pseudomonas aeruginosa Infections in Cystic Fibrosis

(2018) Michael D. Parkins et al.   CLINICAL MICROBIOLOGY REVIEWS

Interplay between MexAB-OprM and MexEF-OprN in clinical isolates of Pseudomonas aeruginosa

(2018) Gertrudis Horna et al.   Scientific Reports

Pseudomonas aeruginosa in Chronic Lung Infections: How to Adapt Within the Host?

(2018) Emmanuel Faure et al.   Frontiers in Immunology

Evolved Aztreonam Resistance Is Multifactorial and Can Produce Hypervirulence in Pseudomonas aeruginosa

(2017) Peter Jorth et al.   mBio

Pseudomonas aeruginosa Lifestyle: A Paradigm for Adaptation, Survival, and Persistence

(2017) M. Fata Moradali et al.   Frontiers in Cellular and Infection Microbiology

Effect of efflux pump inhibition on Pseudomonas aeruginosa transcriptome and virulence

(2017) Giordano Rampioni et al.   Scientific Reports

Pseudomonas aeruginosa Evolutionary Adaptation and Diversification in Cystic Fibrosis Chronic Lung Infections

(2016) Craig Winstanley et al.   TRENDS IN MICROBIOLOGY

Regional Isolation Drives Bacterial Diversification within Cystic Fibrosis Lungs

(2015) Peter Jorth et al.   Cell Host & Microbe

Precision-engineering the Pseudomonas aeruginosa genome with two-step allelic exchange

(2015) Laura R Hmelo et al.   Nature Protocols

Essential genome ofPseudomonas aeruginosain cystic fibrosis sputum

(2015) Keith H. Turner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fitness cost of antibiotic susceptibility during bacterial infection

(2015) Damien Roux et al.   Science Translational Medicine

Pediatric Cystic Fibrosis Sputum Can Be Chemically Dynamic, Anoxic, and Extremely Reduced Due to Hydrogen Sulfide Formation

(2015) Elise S. Cowley et al.   mBio

Recombination is a key driver of genomic and phenotypic diversity in a Pseudomonas aeruginosa population during cystic fibrosis infection

(2015) Sophie E. Darch et al.   Scientific Reports

Convergent evolution and adaptation of Pseudomonas aeruginosa within patients with cystic fibrosis

(2014) Rasmus Lykke Marvig et al.   NATURE GENETICS

Sequence-Verified Two-Allele Transposon Mutant Library for Pseudomonas aeruginosa PAO1

(2012) Kiara Held et al.   JOURNAL OF BACTERIOLOGY

Innate immune responses to Pseudomonas aeruginosa infection

(2011) Elise G. Lavoie et al.   MICROBES AND INFECTION

Efflux Pumps, OprD Porin, AmpC  -Lactamase, and Multiresistance in Pseudomonas aeruginosa Isolates from Cystic Fibrosis Patients

(2010) M. Tomas et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Parallel Evolution in Pseudomonas aeruginosa over 39,000 Generations In Vivo

(2010) H. K. Huse et al.   mBio

Efflux pump inhibitors reduce the invasiveness of Pseudomonas aeruginosa

(2009) Yoichi Hirakata et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Disruption of the CFTR Gene Produces a Model of Cystic Fibrosis in Newborn Pigs

(2008) C. S. Rogers et al.   SCIENCE