Journal
PATHOGENS
Volume 11, Issue 1, Pages -Publisher
MDPI
DOI: 10.3390/pathogens11010079
Keywords
porcine deltacoronaviruses; origin; evolution; cross-species transmission; zoonosis
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Funding
- College of Food, Agricultural and Environmental Sciences, The Ohio State University [2020-009]
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Porcine deltacoronavirus (PDCoV) is an emerging enteropathogenic coronavirus that causes acute diarrhea in piglets and shows zoonotic potential, infecting other animals including humans. It is crucial to comprehensively understand its origin, evolution, cross-species transmission, and zoonotic potential.
Porcine deltacoronavirus (PDCoV) is an emerging enteropathogenic coronavirus of swine that causes acute diarrhoea, vomiting, dehydration and mortality in seronegative neonatal piglets. PDCoV was first reported in Hong Kong in 2012 and its etiological features were first characterized in the United States in 2014. Currently, PDCoV is a concern due to its broad host range, including humans. Chickens, turkey poults, and gnotobiotic calves can be experimentally infected by PDCoV. Therefore, as discussed in this review, a comprehensive understanding of the origin, evolution, cross-species transmission and zoonotic potential of epidemic PDCoV strains is urgently needed.
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