Role of Fibroblasts and Myofibroblasts on the Pathogenesis and Treatment of Pelvic Organ Prolapse

Single-cell transcriptome profiling of the vaginal wall in women with severe anterior vaginal prolapse

(2021) Yaqian Li et al.   Nature Communications

Animal experimental research assessing urogynecologic surgical mesh implants: Outcome measures describing the host response, a systematic review and meta‐analysis

(2021) Kim W. J. Verhorstert et al.   NEUROUROLOGY AND URODYNAMICS

Evaluation of the short‐term host response and biomechanics of an absorbable poly‐4‐hydroxybutyrate scaffold in a sheep model following vaginal implantation

(2021) Chantal M. Diedrich et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Tissue engineering in female pelvic floor reconstruction

(2020) Xiaotong Wu et al.   ENGINEERING IN LIFE SCIENCES

Extracellular Matrix Stiffness and Composition Regulate the Myofibroblast Differentiation of Vaginal Fibroblasts

(2020) Alejandra M. Ruiz-Zapata et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Emerging Nano/Micro-Structured Degradable Polymeric Meshes for Pelvic Floor Reconstruction

(2020) Kallyanashis Paul et al.   Nanomaterials

Mesh induced fibrosis: The protective role of T regulatory cells

(2019) Amanda M. Artsen et al.   Acta Biomaterialia

Landmarks in vaginal mesh development: polypropylene mesh for treatment of SUI and POP

(2019) Naşide Mangir et al.   Nature Reviews Urology

Physicochemically Tuned Myofibroblasts for Wound Healing Strategy

(2019) Ung Hyun Ko et al.   Scientific Reports

Biomechanical Properties of the Pelvic Floor and its Relation to Pelvic Floor Disorders

(2018) Alejandra M. Ruiz-Zapata et al.   EUROPEAN UROLOGY SUPPLEMENTS

Effect of Optimized Concentrations of Basic Fibroblast Growth Factor and Epidermal Growth Factor on Proliferation of Fibroblasts and Expression of Collagen: Related to Pelvic Floor Tissue Regeneration

(2018) Jian-Liu Wang et al.   CHINESE MEDICAL JOURNAL

Fibroblasts and wound healing: an update

(2018) Heather E desJardins-Park et al.   Regenerative Medicine

Gentle cyclic straining of human fibroblasts on electrospun scaffolds enhances their regenerative potential

(2018) Mahshid Vashaghian et al.   Acta Biomaterialia

Effects of ultralow topical estriol dose on vaginal health and quality of life in postmenopausal women who underwent surgical treatment for pelvic organ prolapse

(2017) Salvatore Caruso et al.   MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY

Extracellular matrix metabolism disorder induced by mechanical strain on human parametrial ligament fibroblasts

(2017) Jie Min et al.   Molecular Medicine Reports

Host response to synthetic mesh in women with mesh complications

(2016) Alexis L. Nolfi et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Textile properties of synthetic prolapse mesh in response to uniaxial loading

(2016) William R. Barone et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Stretch-induced Activation of Transforming Growth Factor-β1in Pulmonary Fibrosis

(2016) Aaron R. Froese et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Exploring the basic science of prolapse meshes

(2016) Rui Liang et al.   CURRENT OPINION IN OBSTETRICS & GYNECOLOGY

Vaginal wall weakness in parous ewes: a potential preclinical model of pelvic organ prolapse

(2016) Natharnia Young et al.   INTERNATIONAL UROGYNECOLOGY JOURNAL

In vivo response to polypropylene following implantation in animal models: a review of biocompatibility

(2016) Michelle Kelly et al.   INTERNATIONAL UROGYNECOLOGY JOURNAL

Silk fibroin scaffold as a potential choice for female pelvic reconstruction: A study on the biocompatibility in abdominal wall, pelvic, and vagina

(2016) Yue Chang et al.   MICROSCOPY RESEARCH AND TECHNIQUE

Toward a new generation of pelvic floor implants with electrospun nanofibrous matrices: A feasibility study

(2016) Mahshid Vashaghian et al.   NEUROUROLOGY AND URODYNAMICS

Comparative Characterization of Vaginal Cells Derived From Premenopausal Women With and Without Severe Pelvic Organ Prolapse

(2016) Hala Kufaishi et al.   Reproductive Sciences

Electrospun Matrices for Pelvic Floor Repair: Effect of Fiber Diameter on Mechanical Properties and Cell Behavior

(2016) Mahshid Vashaghian et al.   TISSUE ENGINEERING PART A

Host reaction to vaginally inserted collagen containing polypropylene implants in sheep

(2015) Andrew Feola et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Effects of Mechanical Stretching on the Morphology and Cytoskeleton of Vaginal Fibroblasts from Women with Pelvic Organ Prolapse

(2015) Sumei Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The impact of boundary conditions on surface curvature of polypropylene mesh in response to uniaxial loading

(2015) William R. Barone et al.   JOURNAL OF BIOMECHANICS

Synthetic surgical meshes used in abdominal wall surgery: Part II-Biomechanical aspects

(2015) S. Todros et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

The role of TIMPs in regulation of extracellular matrix proteolysis

(2015) Valerie Arpino et al.   MATRIX BIOLOGY

Attachment of Primary Vaginal Fibroblasts to Absorbable and Nonabsorbable Implant Materials Coated With Platelet-Rich Plasma

(2015) Sebastian Medel et al.   Female Pelvic Medicine and Reconstructive Surgery

Local Oestrogen for Pelvic Floor Disorders: A Systematic Review

(2015) M. A. Weber et al.   PLoS One

Differential expression profiling of matrix metalloproteinases and tissue inhibitors of metalloproteinases in females with or without pelvic organ prolapse

(2014) XIAOHONG WANG et al.   Molecular Medicine Reports

The outcome of transobturator anterior vaginal wall prolapse repair using porcine dermis graft: intermediate term follow-up

(2014) Ayman Mahdy et al.   International Braz J Urol

Comparison of candidate scaffolds for tissue engineering for stress urinary incontinence and pelvic organ prolapse repair

(2013) Altaf Mangera et al.   BJU INTERNATIONAL

Fibroblasts from women with pelvic organ prolapse show differential mechanoresponses depending on surface substrates

(2013) Alejandra M. Ruiz-Zapata et al.   INTERNATIONAL UROGYNECOLOGY JOURNAL

Comparison between trans-obturator trans-vaginal mesh and traditional anterior colporrhaphy in the treatment of anterior vaginal wall prolapse: results of a French RCT

(2013) R. de Tayrac et al.   INTERNATIONAL UROGYNECOLOGY JOURNAL

Elongation of textile pelvic floor implants under load is related to complete loss of effective porosity, thereby favoring incorporation in scar plates

(2013) Jens Otto et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Static and dynamic nanomechanical properties of human skin tissue using atomic force microscopy: Effect of scarring in the upper dermis

(2012) C.A. Grant et al.   Acta Biomaterialia

Deterioration in biomechanical properties of the vagina following implantation of a high-stiffness prolapse mesh

(2012) A Feola et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Vaginal degeneration following implantation of synthetic mesh with increased stiffness

(2012) R Liang et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Decreased expression of elastin, fibulin-5 and lysyl oxidase-like 1 in the uterosacral ligaments of postmenopausal women with pelvic organ prolapse

(2012) Bai-hui Zhao et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH

The myofibroblast matrix: implications for tissue repair and fibrosis

(2012) Franco Klingberg et al.   JOURNAL OF PATHOLOGY

Matrix Metalloproteinase-9 Genetic Polymorphisms and the Risk for Advanced Pelvic Organ Prolapse

(2012) Jennifer M. Wu et al.   OBSTETRICS AND GYNECOLOGY

Primary surgical repair of anterior vaginal prolapse: a randomised trial comparing anatomical and functional outcome between anterior colporrhaphy and trocar-guided transobturator anterior mesh

(2011) A Vollebregt et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Pelvic floor disorders: linking genetic risk factors to biochemical changes

(2011) Lysanne Campeau et al.   BJU INTERNATIONAL

Three-year results from a preclinical implantation study of a long-term resorbable surgical mesh with time-dependent mechanical characteristics

(2011) H. Hjort et al.   Hernia

The Effect of Prolapse Surgery on Vaginal Sensibility

(2011) Mariëlle M.E. Lakeman et al.   Journal of Sexual Medicine

Comparative Analysis of Histopathologic Effects of Synthetic Meshes Based on Material, Weight, and Pore Size in Mice

(2011) Sean B. Orenstein et al.   JOURNAL OF SURGICAL RESEARCH

Anterior Colporrhaphy versus Transvaginal Mesh for Pelvic-Organ Prolapse

(2011) Daniel Altman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Primary and repeat surgical treatment for female pelvic organ prolapse and incontinence in parous women in the UK: a register linkage study

(2011) M. Abdel-fattah et al.   BMJ Open

Trends in inpatient prolapse procedures in the United States, 1979–2006

(2010) Keisha A. Jones et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Evaluating the porcine dermis graft InteXen® in three-compartment transvaginal pelvic organ prolapse repair

(2010) Rajeev Ramanah et al.   INTERNATIONAL UROGYNECOLOGY JOURNAL

LOX family enzymes expression in vaginal tissue of premenopausal women with severe pelvic organ prolapse

(2010) May Alarab et al.   INTERNATIONAL UROGYNECOLOGY JOURNAL

Factors Affecting Wound Healing

(2010) S. Guo et al.   JOURNAL OF DENTAL RESEARCH

Endothelin-1 and Transforming Growth Factor-β1 Independently Induce Fibroblast Resistance to Apoptosis via AKT Activation

(2009) Priya Kulasekaran et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Reoperation 10 years after surgically managed pelvic organ prolapse and urinary incontinence

(2008) Mary Anna Denman et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Pelvic Floor Anatomy and Applied Physiology

(2008) Varuna Raizada et al.   GASTROENTEROLOGY CLINICS OF NORTH AMERICA

Mesh terminology 101

(2008) W. S. Cobb et al.   Hernia

The contractile properties of vaginal myofibroblasts: Is the myofibroblasts contraction force test a valuable indication of future prolapse development?

(2008) S. Meyer et al.   INTERNATIONAL UROGYNECOLOGY JOURNAL

Changes in connective tissue in patients with pelvic organ prolapse—a review of the current literature

(2008) M. H. Kerkhof et al.   INTERNATIONAL UROGYNECOLOGY JOURNAL

Wound repair and regeneration

(2008) Geoffrey C. Gurtner et al.   NATURE

In vitro degradation and in vivo biocompatibility of poly(lactic acid) mesh for soft tissue reinforcement in vaginal surgery

(2007) Renaud de Tayrac et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS