Options to Improve the Action of PROTACs in Cancer: Development of Controlled Delivery Nanoparticles
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Options to Improve the Action of PROTACs in Cancer: Development of Controlled Delivery Nanoparticles
Authors
Keywords
-
Journal
Frontiers in Cell and Developmental Biology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2022-02-03
DOI
10.3389/fcell.2021.805336
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Targeting pan-essential genes in cancer: challenges and opportunities
- (2021) Liang Chang et al. CANCER CELL
- Activatable polymer nanoagonist for second near-infrared photothermal immunotherapy of cancer
- (2021) Yuyan Jiang et al. Nature Communications
- Biodegradable Polymeric Nanoparticles for Drug Delivery to Solid Tumors
- (2021) Agnese Gagliardi et al. Frontiers in Pharmacology
- Current approaches in lipid-based nanocarriers for oral drug delivery
- (2021) María Plaza-Oliver et al. Drug Delivery and Translational Research
- Ubiquitination of Nonhistone Proteins in Cancer Development and Treatment
- (2021) Xiuzhen Zhang et al. Frontiers in Oncology
- Design of liposomes as drug delivery system for therapeutic applications
- (2021) Diana Guimarães et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Advanced nanomedicine and cancer: Challenges and opportunities in clinical translation
- (2021) Juan Gonzalez-Valdivieso et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Cancer Selective Target Degradation by Folate-Caged PROTACs
- (2021) Jing Liu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Targeted protein degraders crowd into the clinic
- (2021) Asher Mullard NATURE REVIEWS DRUG DISCOVERY
- PROTAC: An Effective Targeted Protein Degradation Strategy for Cancer Therapy
- (2021) Si-Min Qi et al. Frontiers in Pharmacology
- From Conception to Development: Investigating PROTACs Features for Improved Cell Permeability and Successful Protein Degradation
- (2021) Carlotta Cecchini et al. Frontiers in Chemistry
- Lipid-Based Nanoparticles in the Clinic and Clinical Trials: From Cancer Nanomedicine to COVID-19 Vaccines
- (2021) Thai Thanh Hoang Thi et al. Vaccines
- Lipid Nanoparticles—From Liposomes to mRNA Vaccine Delivery, a Landscape of Research Diversity and Advancement
- (2021) Rumiana Tenchov et al. ACS Nano
- The Future of Medicinal Chemistry, PROTAC, and Undruggable Drug Targets
- (2021) Antti Poso JOURNAL OF MEDICINAL CHEMISTRY
- Unraveling the Role of Linker Design in Proteolysis Targeting Chimeras
- (2021) Troy A. Bemis et al. JOURNAL OF MEDICINAL CHEMISTRY
- Polyester Polymeric Nanoparticles as Platforms in the Development of Novel Nanomedicines for Cancer Treatment
- (2021) Enrique Niza et al. Cancers
- Light-Controllable PROTACs for Temporospatial Control of Protein Degradation
- (2021) Jing Liu et al. Frontiers in Cell and Developmental Biology
- KRAS Inhibitors– yes but what next? Direct targeting of KRAS– vaccines, adoptive T cell therapy and beyond
- (2021) Misako Nagasaka et al. CANCER TREATMENT REVIEWS
- VHL-based PROTACs as potential therapeutic agents: Recent progress and perspectives
- (2021) Chao Wang et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Developments of CRBN-based PROTACs as potential therapeutic agents
- (2021) Chao Wang et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Review of the development of BTK inhibitors in overcoming the clinical limitations of ibrutinib
- (2021) Fansheng Ran et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Nanomedicine for increasing the oral bioavailability of cancer treatments
- (2021) Alessandro Parodi et al. JOURNAL OF NANOBIOTECHNOLOGY
- Inhibitors, PROTACs and Molecular Glues as Diverse Therapeutic Modalities to Target Cyclin-Dependent Kinase
- (2021) Sandeep Rana et al. Cancers
- Safety and efficacy of iron supplementation after myocardial infarction in mice with moderate blood loss anaemia
- (2021) Patricia Wischmann et al. ESC Heart Failure
- Antibody–PROTAC Conjugates Enable HER2-Dependent Targeted Protein Degradation of BRD4
- (2020) Marı́a Maneiro et al. ACS Chemical Biology
- Targeted degradation of anaplastic lymphoma kinase by gold nanoparticle-based multi-headed proteolysis targeting chimeras
- (2020) Yingming Wang et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- PROteolysis TArgeting Chimeras (PROTACs) as emerging anticancer therapeutics
- (2020) Sajid Khan et al. ONCOGENE
- Oral Drug Delivery with Nanoparticles into the Gastrointestinal Mucosa
- (2020) Jiao Liu et al. FUNDAMENTAL & CLINICAL PHARMACOLOGY
- Lysosome-targeting chimaeras for degradation of extracellular proteins
- (2020) Steven M. Banik et al. NATURE
- Understanding and Improving the Membrane Permeability of VH032-Based PROTACs
- (2020) Victoria G. Klein et al. ACS Medicinal Chemistry Letters
- Systematic Investigation of the Permeability of Androgen Receptor PROTACs
- (2020) Duncan E. Scott et al. ACS Medicinal Chemistry Letters
- Antibody-Drug Conjugates: A Promising Novel Therapy for the Treatment of Ovarian Cancer
- (2020) Aranzazu Manzano et al. Cancers
- First orally bioavailable prodrug of proteolysis targeting chimera (PROTAC) degrades cyclin-dependent kinases 2/4/6 in vivo
- (2020) Mingming Wei et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Antibody Conjugation of Nanoparticles as Therapeutics for Breast Cancer Treatment
- (2020) Alberto Juan et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Delivering the power of nanomedicine to patients today
- (2020) Matthieu Germain et al. JOURNAL OF CONTROLLED RELEASE
- Proteolysis targeting chimeras (PROTACs) in cancer therapy
- (2020) Alberto Ocaña et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- PROTAC-DB: an online database of PROTACs
- (2020) Gaoqi Weng et al. NUCLEIC ACIDS RESEARCH
- Nanoformulation of BRD4-Degrading PROTAC: Improving Druggability To Target the ‘Undruggable’ MYC in Pancreatic Cancer
- (2020) Tamara Minko TRENDS IN PHARMACOLOGICAL SCIENCES
- An Overview of Antibody Conjugated Polymeric Nanoparticles for Breast Cancer Therapy
- (2020) Alberto Juan et al. Pharmaceutics
- Controlled Delivery of BET-PROTACs: In Vitro Evaluation of MZ1-Loaded Polymeric Antibody Conjugated Nanoparticles in Breast Cancer
- (2020) Francisco J. Cimas et al. Pharmaceutics
- Engineering precision nanoparticles for drug delivery
- (2020) Michael J. Mitchell et al. NATURE REVIEWS DRUG DISCOVERY
- Iron oxide nanoparticles: Diagnostic, therapeutic and theranostic applications
- (2019) Seyed Mohammadali Dadfar et al. ADVANCED DRUG DELIVERY REVIEWS
- The PROTAC technology in drug development
- (2019) Yutian Zou et al. CELL BIOCHEMISTRY AND FUNCTION
- Modelling dose and schedule effects of AZD2811 nanoparticles targeting aurora kinase B for treatment of diffuse large B-cell lymphoma
- (2019) Nicolas Floc'h et al. MOLECULAR CANCER THERAPEUTICS
- From poly(alkyl cyanoacrylate) to squalene as core material for the design of nanomedicines
- (2019) Simona Mura et al. JOURNAL OF DRUG TARGETING
- BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design
- (2019) William Farnaby et al. Nature Chemical Biology
- Cytotoxicity of Dendrimers
- (2019) Janaszewska et al. Biomolecules
- PROTACs as Potential Therapeutic Agents for Cancer Drug Resistance
- (2019) Xiuyun Sun et al. BIOCHEMISTRY
- Light-Induced Protein Degradation with Photocaged PROTACs
- (2019) Gang Xue et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Smart cancer nanomedicine
- (2019) Roy van der Meel et al. Nature Nanotechnology
- A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity
- (2019) Sajid Khan et al. NATURE MEDICINE
- Trastuzumab-Targeted Biodegradable Nanoparticles for Enhanced Delivery of Dasatinib in HER2+ Metastasic Breast Cancer
- (2019) Enrique Niza et al. Nanomaterials
- Niosomes, an alternative for liposomal delivery
- (2018) Rianne Bartelds et al. PLoS One
- Abstract 5236: ARV-110: An androgen receptor PROTAC degrader for prostate cancer
- (2018) Taavi Neklesa et al. CANCER RESEARCH
- The Endosomal Escape of Nanoparticles: Toward More Efficient Cellular Delivery
- (2018) Samuel A. Smith et al. BIOCONJUGATE CHEMISTRY
- Enhanced anticancer activity and oral bioavailability of ellagic acid through encapsulation in biodegradable polymeric nanoparticles
- (2017) Fatma Mady et al. International Journal of Nanomedicine
- Magnetic nanoparticles for precision oncology: theranostic magnetic iron oxide nanoparticles for image-guided and targeted cancer therapy
- (2017) Lei Zhu et al. Nanomedicine
- Targeted protein degradation by PROTACs
- (2017) Taavi K. Neklesa et al. PHARMACOLOGY & THERAPEUTICS
- Cotransporting Ion is a Trigger for Cellular Endocytosis of Transporter-Targeting Nanoparticles: A Case Study of High-Efficiency SLC22A5 (OCTN2)-Mediated Carnitine-Conjugated Nanoparticles for Oral Delivery of Therapeutic Drugs
- (2017) Longfa Kou et al. Advanced Healthcare Materials
- Systemic delivery of siRNA via targeted nanoparticles in patients with cancer: Results from a first-in-class phase I clinical trial.
- (2017) A. Ribas et al. JOURNAL OF CLINICAL ONCOLOGY
- Paclitaxel injection concentrate for nanodispersion versus nab-paclitaxel in women with metastatic breast cancer: a multicenter, randomized, comparative phase II/III study
- (2016) Minish M. Jain et al. BREAST CANCER RESEARCH AND TREATMENT
- Phase I Study of PSMA-Targeted Docetaxel-Containing Nanoparticle BIND-014 in Patients with Advanced Solid Tumors
- (2016) D. D. Von Hoff et al. CLINICAL CANCER RESEARCH
- A phase 2 study of BIND-014 (PSMA-targeted docetaxel nanoparticle) administered to patients with chemotherapy-naïve metastatic castration-resistant prostate cancer (mCRPC).
- (2016) Karen A. Autio et al. JOURNAL OF CLINICAL ONCOLOGY
- Shape control of inorganic nanoparticles from solution
- (2016) Zhaohui Wu et al. Nanoscale
- Protein Degradation by In-Cell Self-Assembly of Proteolysis Targeting Chimeras
- (2016) Honorine Lebraud et al. ACS Central Science
- Quantitative Analysis of Thiolated Ligand Exchange on Gold Nanoparticles Monitored by 1H NMR Spectroscopy
- (2015) Ashley M. Smith et al. ANALYTICAL CHEMISTRY
- Trastuzumab guided nanotheranostics: A lipid based multifunctional nanoformulation for targeted drug delivery and imaging in breast cancer therapy
- (2015) Priyambada Parhi et al. JOURNAL OF COLLOID AND INTERFACE SCIENCE
- Catalytic in vivo protein knockdown by small-molecule PROTACs
- (2015) Daniel P Bondeson et al. Nature Chemical Biology
- Phthalimide conjugation as a strategy for in vivo target protein degradation
- (2015) G. E. Winter et al. SCIENCE
- Antitumoral activity of the mithralog EC-8042 in triple negative breast cancer linked to cell cycle arrest in G2
- (2015) Atanasio Pandiella et al. Oncotarget
- Advances and Challenges of Liposome Assisted Drug Delivery
- (2015) Lisa Sercombe et al. Frontiers in Pharmacology
- Polymeric Nanoparticle Technologies for Oral Drug Delivery
- (2014) Eric M. Pridgen et al. Clinical Gastroenterology and Hepatology
- 41 Clinical activity of BIND-014 (docetaxel nanoparticles for injectable suspension) as second-line therapy in patients (pts) with Stage III/IV non-small cell lung cancer
- (2014) R. Natale et al. EUROPEAN JOURNAL OF CANCER
- Tumour heterogeneity and the evolution of polyclonal drug resistance
- (2014) Rebecca A. Burrell et al. Molecular Oncology
- Correlating animal and human phase Ia/Ib clinical data with CALAA-01, a targeted, polymer-based nanoparticle containing siRNA
- (2014) J. E. Zuckerman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Orally administered liposomal formulations for colon targeted drug delivery
- (2014) Susan Hua Frontiers in Pharmacology
- Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor–Resistant Disease
- (2013) Kadoaki Ohashi et al. JOURNAL OF CLINICAL ONCOLOGY
- Posttranslational protein knockdown coupled to receptor tyrosine kinase activation with phosphoPROTACs
- (2013) J. Hines et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Small-Molecule Inhibitors of the Interaction between the E3 Ligase VHL and HIF1α
- (2012) Dennis L. Buckley et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Oral drug delivery with polymeric nanoparticles: The gastrointestinal mucus barriers
- (2011) Laura M. Ensign et al. ADVANCED DRUG DELIVERY REVIEWS
- Acquired resistance to drugs targeting receptor tyrosine kinases
- (2011) Steven A. Rosenzweig BIOCHEMICAL PHARMACOLOGY
- Protein Knockdown Using Methyl Bestatin−Ligand Hybrid Molecules: Design and Synthesis of Inducers of Ubiquitination-Mediated Degradation of Cellular Retinoic Acid-Binding Proteins
- (2010) Yukihiro Itoh et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Impact of linker length on the activity of PROTACs
- (2010) Kedra Cyrus et al. Molecular BioSystems
- Nanopharmacy: Inorganic nanoscale devices as vectors and active compounds
- (2010) Pilar Rivera Gil et al. PHARMACOLOGICAL RESEARCH
- Identification of a Primary Target of Thalidomide Teratogenicity
- (2010) T. Ito et al. SCIENCE
- Phase II Clinical Trial of Paclitaxel Loaded Polymeric Micelle in Patients with Advanced Pancreatic Cancer
- (2009) Muhammad W. Saif et al. CANCER INVESTIGATION
- Current advances in research and clinical applications of PLGA-based nanotechnology
- (2009) Jian-Ming Lü et al. EXPERT REVIEW OF MOLECULAR DIAGNOSTICS
- Targeted intracellular protein degradation induced by a small molecule: En route to chemical proteomics
- (2008) Ashley R. Schneekloth et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started