Review
Health Care Sciences & Services
Scarlet Nazarian, Ben Glover, Hutan Ashrafian, Ara Darzi, Julian Teare
Summary: Artificial intelligence technologies show great potential in improving the detection and characterization of colorectal polyps, ultimately reducing the incidence of colorectal cancer. The current generation of AI-based systems demonstrate impressive accuracy in detecting and characterizing colorectal polyps.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Review
Health Care Sciences & Services
Yoon Suk Jung, Jung Ho Park, Chan Hyuk Park
Summary: Patients under the age of 50 who have undergone polypectomy have a lower risk of metachronous advanced colorectal neoplasia (ACRN) compared to older patients (>= 50 years), indicating that they do not require more intensive surveillance and can have extended surveillance intervals.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Review
Gastroenterology & Hepatology
Yoon Suk Jung, Jung Ho Park, Chan Hyuk Park
Summary: This study found no significant difference in the risk of metachronous colorectal neoplasia between serrated polyps and conventional adenomas, supporting current surveillance guidelines. Patients with both serrated polyps and high-risk adenomas may have an increased risk, warranting further investigation.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Review
Medicine, General & Internal
Cesare Hassan, Marco Spadaccini, Yuichi Mori, Farid Foroutan, Antonio Facciorusso, Paraskevas Gkolfakis, Georgios Tziatzios, Konstantinos Triantafyllou, Giulio Antonelli, Kareem Khalaf, Tommy Rizkala, Per Olav Vandvik, Alessandro Fugazza, Emanuele Rondonotti, Jeremy R. Glissen-Brown, Shunsuke Kamba, Marcello Maida, Loredana Correale, Pradeep Bhandari, Rodrigo Jover, Prateek Sharma, Douglas K. Rex, Alessandro Repici
Summary: Artificial intelligence computer-aided detection (CADe) during colonoscopy can increase adenoma detection rates (ADRs) and reduce adenoma miss rates, but may also lead to overdiagnosis and overtreatment of nonneoplastic polyps.
ANNALS OF INTERNAL MEDICINE
(2023)
Article
Biochemical Research Methods
Wei-Chih Liao, Arvind Mukundan, Cleorita Sadiaza, Yu-Ming Tsao, Chien-Wei Huang, Hsiang-Chen Wang
Summary: This study evaluates a complete meta-analysis of selected studies that only use hyperspectral imaging to detect esophageal cancer, showing that these methods have high accuracy but lack external validation.
BIOMEDICAL OPTICS EXPRESS
(2023)
Review
Gastroenterology & Hepatology
Sagar Shah, Nathan Park, Nabil El Hage Chehade, Anastasia Chahine, Marc Monachese, Amelie Tiritilli, Zain Moosvi, Ronald Ortizo, Jason Samarasena
Summary: This study demonstrates that computer-aided colonoscopy (CAC) can effectively reduce the miss rates of adenomas and sessile serrated lesions, increase the adenoma detection rate, and improve the detection of adenomas larger than 10 mm.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Psychology, Mathematical
Javier Virues-Ortega, Candida Delgado Casas, Neil Martin, Aida Tarifa-Rodriguez, Antonio Jesus Reina Hidalgo, Alison D. Cox, Jose Navarro Guzman
Summary: Computer-aided behavior observation is replacing paper-and-pencil approaches, but the relative accuracy of these methods is not well established. This study evaluated the accuracy of paper-and-pencil observation and two computer-aided methods, finding that paper-and-pencil observation had slightly better accuracy and that the number of recordable events influenced accuracy.
BEHAVIOR RESEARCH METHODS
(2023)
Review
Surgery
Jiawei Bai, Kai Liu, Li Gao, Xin Zhao, Shaohua Zhu, Ying Han, Zhiguo Liu
Summary: This study evaluated the diagnostic accuracy of computer-aided diagnosis (CAD) algorithms in predicting the invasion depth of early colorectal cancer (CRC) and compared it to the performance of endoscopists. The results showed that in Japan/Korea-based studies, the CAD algorithms had comparable performance to all endoscopists but were inferior to expert endoscopists. In China-based studies, the CAD algorithms performed better than all endoscopists. Overall, while the CAD algorithms showed comparable accuracy in predicting the invasion depth of early CRC, further improvements are needed before their extensive application in clinical practice.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Review
Gastroenterology & Hepatology
Russell D. Dolan, Ahmad Najdat Bazarbashi, Thomas R. McCarty, Christopher C. Thompson, Hiroyuki Aihara
Summary: Endoscopic full-thickness resection (EFTR) is an effective modality for the resection of colorectal lesions, with high technical success and margin-negative (R-0) resection rate and a relatively low risk of adverse events and recurrence. Lesion size has an impact on R-0 resection rate and overall procedure-associated adverse event rates, with larger lesions associated with lower R-0 resection rate and higher adverse event rates.
GASTROINTESTINAL ENDOSCOPY
(2022)
Review
Gastroenterology & Hepatology
Thomas R. McCarty, Ahmad Najdat Bazarbashi, Christopher C. Thompson, Hiroyuki Aihara
Summary: Hybrid endoscopic submucosal dissection (ESD) is safe and effective for removal of colorectal lesions, with shorter procedure duration, fewer complications, and no significant difference in recurrence and surgery rates compared to conventional ESD; however, it has a lower en bloc resection rate.
Review
Dentistry, Oral Surgery & Medicine
Adria Jorba-Garcia, Albert Gonzalez-Barnadas, Octavi Camps-Font, Rui Figueiredo, Eduard Valmaseda-Castellon
Summary: The study assessed the accuracy of dynamic computer-aided implant surgery systems in placing dental implants, finding that these systems are more accurate than static computer-aided implant surgery systems and freehand implant placement.
CLINICAL ORAL INVESTIGATIONS
(2021)
Review
Oncology
Yunfei Xiao, Juan Li, Jiamei Zhong, Dequan Chen, Jianbo Shi, Hongrui Jin
Summary: Quantitative analysis of DWI-MRI has high diagnostic value in detecting colorectal cancer, accurately identifying malignant tumors in soft tissues.
FRONTIERS IN ONCOLOGY
(2022)
Article
Medicine, General & Internal
Hiroaki Matsui, Shunsuke Kamba, Hideka Horiuchi, Sho Takahashi, Masako Nishikawa, Akihiro Fukuda, Aya Tonouchi, Natsumaro Kutsuna, Yuki Shimahara, Naoto Tamai, Kazuki Sumiyama
Summary: Researchers developed and evaluated a CADe system based on YOLO v3 for detecting and localizing colorectal lesions, demonstrating its accuracy and speed in detecting lesions from video data, reducing operator biases.
Review
Gastroenterology & Hepatology
Alyssa Y. Choi, Zain Moosvi, Sagar Shah, Mary Kathryn Roccato, Andrew Y. Wang, Christopher M. Hamerski, Jason B. Samarasena
Summary: The systematic review and meta-analysis showed that underwater EMR (UEMR) is a safe and effective alternative to conventional EMR (CEMR) for the resection of colorectal polyps, especially for polyps equal to or larger than 20 mm. With appropriate training, UEMR may be considered as a first-line option for resection of colorectal polyps.
GASTROINTESTINAL ENDOSCOPY
(2021)
Review
Gastroenterology & Hepatology
Liya Lu, Sara Koo, Stuart McPherson, Mark A. Hull, Colin J. Rees, Linda Sharp
Summary: Metabolic syndrome is associated with poorer colorectal cancer-specific survival, but there is inconsistent evidence regarding metachronous neoplasia.
COLORECTAL DISEASE
(2022)
Review
Gastroenterology & Hepatology
Virginia Solitano, Antonio Facciorusso, Tine Jess, Christopher Ma, Cesare Hassan, Alessandro Repici, Vipul Jairath, Alessandro Armuzzi, Siddharth Singh
Summary: In patients with inflammatory bowel diseases (IBDs), no significant difference in the risk of serious infections was observed between advanced therapies. Vedolizumab may have a lower risk of serious infections compared to TNFa antagonists in patients with ulcerative colitis, but not in Crohn's disease. Ustekinumab may be more effective than TNFa antagonists and vedolizumab in patients with Crohn's disease.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Review
Gastroenterology & Hepatology
Edoardo Vespa, Gaia Pellegatta, Viveksandeep T. Chandrasekar, Marco Spadaccini, Harsh Patel, Roberta Maselli, Piera A. Galtieri, Elisa Carlani, Prateek Sharma, Cesare Hassan, Alessandro Repici
Summary: Long-term clinical efficacy of POEM persisted in 87% of patients with achalasia. Post-POEM symptomatic reflux remained stable over time. The risk for Barrett's esophagus and peptic strictures appeared minimal.
Article
Gastroenterology & Hepatology
Yuichi Mori, Pu Wang, Magnus Loberg, Masashi Misawa, Alessandro Repici, Marco Spadaccini, Loredana Correale, Giulio Antonelli, Honggang Yu, Dexin Gong, Misaki Ishiyama, Shin-ei Kudo, Shunsuke Kamba, Kazuki Sumiyama, Yutaka Saito, Haruo Nishino, Peixi Liu, Jeremy R. Glissen Brown, Nabil M. Mansour, Seth A. Gross, Mette Kalager, Michael Bretthauer, Douglas K. Rex, Prateek Sharma, Tyler M. Berzin, Cesare Hassan
Summary: The use of AI during colonoscopy increases the proportion of patients needing intensive surveillance by approximately 35% in the United States and 20% in Europe. This contributes to improved cancer prevention but adds significant patient burden and healthcare costs.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Gastroenterology & Hepatology
Francesco Auriemma, Emanuele Dabizzi, Antonio Facciorusso, Silvia Carrara, Germana de Nucci, Giampiero Manes, Laura Lamonaca, Danilo Paduano, Andrew Ofosu, Stefano Francesco Crino, Alessandro Repici, Benedetto Mangiavillano
Summary: This study aimed to evaluate the diagnostic accuracy of EUS plus FNA/FNB in suspected local recurrence of pelvic masses. The results showed that EUS-FNB had higher sensitivity and lower uncertainty in diagnosing pelvic masses, highlighting its importance in oncological follow-up.
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
(2023)
Review
Gastroenterology & Hepatology
Antonio Facciorusso, Stefano Francesco Crino, Daryl Ramai, Deepak Madhu, Alessandro Fugazza, Silvia Carrara, Marco Spadaccini, Benedetto Mangiavillano, Paraskevas Gkolfakis, Babu P. Mohan, Cesare Hassan, Alessandro Repici
Summary: A systematic review and network meta-analysis compared tissue sampling techniques for EUS-guided fine-needle biopsy of pancreatic masses. The modified wet suction technique showed the highest sample adequacy, while the no-suction technique performed the worst. Dry suction had higher rates of blood contamination compared to slow-pull technique, but no suction resulted in less blood contamination. The modified wet-suction technique also had better tissue integrity than dry suction.
GASTROINTESTINAL ENDOSCOPY
(2023)
Editorial Material
Gastroenterology & Hepatology
Cesare Hassan, Alessandro Repici, Tommy Rizkala, Michal F. F. Kaminski
ENDOSCOPY INTERNATIONAL OPEN
(2023)
Article
Gastroenterology & Hepatology
Kien Vu Trung, Einas Abou-Ali, Fabrice H. Caillol, Woo Paik, Bertrand Napoleon, Viliam E. Masaryk, Sophia van der Wiel, Enrique Perez-Cuadrado-Robles, Nicolas Musquer, Asif Halimi, Kevin R. Soares, Francois Souche, Steffen C. Seyfried, Maria Petrone, Stefano Crippa, Tobias Kleemann, David J. Albers, Tobias Weismueller, Ana Dugic, Benjamin Meier, Edris Wedi, Moritz Schiemer, Sara Regner, Sebastien Gaujoux, Marcus Hollenbach, Francesco Auriemma, Aiste Gulla, Elias Karam, Marc Giovannini, Jean-Philippe Ratone, Uwe Will, Rita Saadeh, Marco J. Bruno, Pierre Deprez, Urban Arnelo, Erik Haraldsson, Alexander Waldthaler, Galen Leung, Mark A. Schattner, William R. Jarnagin, Tiegong Wang, Jean M. Fabre, Georg Kaehler, Alberto Mariani, Piera Zaccari, Giulio Belfiori, Massimo Falconi, Stefano Partelli, Alessandro Repici, Andrea Anderloni, Johanna Laukkarinen, Albrecht Hoffmeister, Jonas Rosendahl, Brigitte Schumacher, Louise Barbier, Dominik Heling, Steffen Muehldorfer, Stephanie Truant, Karel Caca, Marcel Tantau, Katrin Salzmann, Patrice David, Arthur Schmidt, Tullio Piardi, J. Matthias Loehr, Johan Gagniere, Bogdan P. Miutescu, Arthur Berger, Peter Schemmer, Christian Heise, Vasile Sandru, Reea Ahola, Mario Dinis-Ribeiro, Tiago Curdia Goncalves, Doerte Wichmann
Summary: This study retrospectively analyzed the outcomes of endoscopic papillectomy in FAP-related and sporadic ampullary lesions. The study found that endoscopic papillectomy is safe and effective for FAP-related ampullary lesions, and FAP patients require long-term surveillance.
Article
Gastroenterology & Hepatology
Ludovica Venezia, Matteo Rossano Buonocore, Ilenia Barbuscio, Francesco Bortoluzzi, Fabio Monica, Guido Manfredi, Andrea Anderloni, Elisa Stasi
Summary: The Italian Association of Hospital Gastroenterologists and Endoscopists (AIGO) released five recommendations to improve the management of gastrointestinal diseases and enhance healthcare quality as part of the 'Choosing Wisely' international campaign.
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
(2023)
Review
Oncology
Raefa Abou Khouzam, Jean-Marie Lehn, Hemma Mayr, Pierre-Alain Clavien, Michael Bradley Wallace, Michel Ducreux, Perparim Limani, Salem Chouaib
Summary: Hypoxia is a crucial characteristic of the tumor microenvironment in pancreatic ductal adenocarcinoma (PDAC) and plays a significant role in its pathogenesis. This review focuses on the impact of hypoxia on genomic instability and the tumor immune microenvironment in PDAC. Strategies for alleviating hypoxia and their potential applications for diagnosis and therapy in PDAC patients will also be discussed.
Review
Biology
Marco Spadaccini, Ludovico Alfarone, Viveksandeep Thoguluva Chandrasekar, Roberta Maselli, Antonio Capogreco, Gianluca Franchellucci, Davide Massimi, Alessandro Fugazza, Matteo Colombo, Silvia Carrara, Antonio Facciorusso, Pradeep Bhandari, Prateek Sharma, Cesare Hassan, Alessandro Repici
Summary: Over the last two decades, endoscopic eradication therapy has become the preferred treatment strategy for patients with Barrett's oesophagus-related dysplasia and early oesophageal adenocarcinoma. Radiofrequency ablation is the first-line option due to its proven effectiveness and safety, although it is expensive and not universally applicable. Cryotherapy techniques and hybrid argon plasma coagulation have shown promising results as potential alternatives to radiofrequency ablation. This review aims to provide a practical guide for the different ablative options for Barrett's oesophagus.
Review
Medicine, General & Internal
Roberta Maselli, Roberto de Sire, Alessandro Fugazza, Marco Spadaccini, Matteo Colombo, Antonio Capogreco, Torsten Beyna, Alessandro Repici
Summary: Ampullary neoplastic lesions are a rare form of cancer that can be sporadic or related to genetic syndromes. They are often asymptomatic but can cause symptoms such as jaundice and pain. Endoscopy, endoscopic ultrasound, and magnetic resonance cholangiopancreatography play a crucial role in the evaluation of these lesions. Endoscopic papillectomy is recognized as an effective treatment.
Article
Gastroenterology & Hepatology
Paraskevas Gkolfakis, Christina Kapizioni, Georgios Tziatzios, Antonio Facciorusso, Leonardo Frazzoni, Konstantinos Thomopoulos, Spyros Potamianos, Dimitrios Christodoulou, Vasilios Papadopoulos, Lorenzo Fuccio, Cesare Hassan, Konstantinos Triantafyllou
Summary: This study evaluated the comparative efficacy of predictive scores in predicting inadequate bowel cleansing among hospitalized patients undergoing colonoscopy. The results showed that Model B outperformed its comparators in predicting inadequate bowel preparation, particularly in mobilized inpatients.
ANNALS OF GASTROENTEROLOGY
(2023)