Model-Informed Precision Dosing during Infliximab Induction Therapy Reduces Variability in Exposure and Endoscopic Improvement between Patients with Ulcerative Colitis
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Title
Model-Informed Precision Dosing during Infliximab Induction Therapy Reduces Variability in Exposure and Endoscopic Improvement between Patients with Ulcerative Colitis
Authors
Keywords
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Journal
Pharmaceutics
Volume 13, Issue 10, Pages 1623
Publisher
MDPI AG
Online
2021-10-09
DOI
10.3390/pharmaceutics13101623
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Note: Only part of the references are listed.- The Effect of Aging on Infliximab Exposure and Response in Patients with Inflammatory Bowel Diseases
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- New Tools for Therapeutic Drug Monitoring: Making Big Things out of Small Pieces
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- Impact of Inaccurate Documentation of Sampling and Infusion Time in Model-Informed Precision Dosing
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- Modelling of the Relationship Between Infliximab Exposure, Faecal Calprotectin, and Endoscopic Remission in Patients with Crohn's Disease
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- Cumulative Exposure to Infliximab, But Not Trough Concentrations, Correlate With Rate of Infection
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- Baseline Clearance of Infliximab is Associated with Requirement for Colectomy in Patients with Acute Severe Ulcerative Colitis
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- Therapeutic drug monitoring of anti-tumor necrosis factor agents: lessons learned and remaining issues
- (2020) Zhigang Wang et al. CURRENT OPINION IN PHARMACOLOGY
- Optimising infliximab induction dosing for patients with ulcerative colitis
- (2019) Erwin Dreesen et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- How, When, and For Whom Should We Perform Therapeutic Drug Monitoring?
- (2019) Severine Vermeire et al. Clinical Gastroenterology and Hepatology
- Increasing Infliximab Dose Based on Symptoms, Biomarkers, and Serum Drug Concentrations Does Not Increase Clinical, Endoscopic, and Corticosteroid-Free Remission in Patients With Active Luminal Crohn’s Disease
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- A Population Pharmacokinetic-Pharmacodynamic Model of Pegfilgrastim
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- American Gastroenterological Association Institute Technical Review on the Role of Therapeutic Drug Monitoring in the Management of Inflammatory Bowel Diseases
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- Third European Evidence-based Consensus on Diagnosis and Management of Ulcerative Colitis. Part 2: Current Management
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- Pharmacokinetic Features and Presence of Antidrug Antibodies Associate With Response to Infliximab Induction Therapy in Patients With Moderate to Severe Ulcerative Colitis
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- Infliximab Concentration Thresholds During Induction Therapy Are Associated With Short-term Mucosal Healing in Patients With Ulcerative Colitis
- (2016) Konstantinos Papamichael et al. Clinical Gastroenterology and Hepatology
- Efficacy of Infliximab Biosimilar CT-P13 Induction Therapy on Mucosal Healing in Ulcerative Colitis
- (2016) Klaudia Farkas et al. Journal of Crohns & Colitis
- Brief Report: Relationship Between Serum Infliximab Concentrations and Risk of Infections in Patients Treated for Spondyloarthritis
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