Enzyme‐constrained models predict the dynamics of Saccharomyces cerevisiae growth in continuous, batch and fed‐batch bioreactors

From Innovation to Application: Bridging the Valley of Death in Industrial Biotechnology

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Medusa: Software to build and analyze ensembles of genome-scale metabolic network reconstructions

(2020) Gregory L. Medlock et al.   PLoS Computational Biology

Protein cost allocation explains metabolic strategies in Escherichia coli

(2020) Pranas Grigaitis et al.   JOURNAL OF BIOTECHNOLOGY

Systems Metabolic Engineering Strategies: Integrating Systems and Synthetic Biology with Metabolic Engineering

(2019) Kyeong Rok Choi et al.   TRENDS IN BIOTECHNOLOGY

Energy metabolism controls phenotypes by protein efficiency and allocation

(2019) Yu Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The common message of constraint-based optimization approaches: overflow metabolism is caused by two growth-limiting constraints

(2019) Daan H. de Groot et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A consensus S. cerevisiae metabolic model Yeast8 and its ecosystem for comprehensively probing cellular metabolism

(2019) Hongzhong Lu et al.   Nature Communications

The important versus the exciting: reining contradictions in contemporary biotechnology

(2018) Víctor de Lorenzo et al.   Microbial Biotechnology

Improving the phenotype predictions of a yeast genome‐scale metabolic model by incorporating enzymatic constraints

(2017) Benjamín J Sánchez et al.   Molecular Systems Biology

COBRApy: COnstraints-Based Reconstruction and Analysis for Python

(2013) Ali Ebrahim et al.   BMC Systems Biology

Constraining the metabolic genotype–phenotype relationship using a phylogeny of in silico methods

(2012) Nathan E. Lewis et al.   NATURE REVIEWS MICROBIOLOGY

Dynamic flux balance modeling of S. cerevisiae and E. coli co-cultures for efficient consumption of glucose/xylose mixtures

(2011) Timothy J. Hanly et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

An in vivo data-driven framework for classification and quantification of enzyme kinetics and determination of apparent thermodynamic data

(2011) André B. Canelas et al.   METABOLIC ENGINEERING

Economics of membrane occupancy and respiro-fermentation

(2011) K. Zhuang et al.   Molecular Systems Biology

Application of dynamic flux balance analysis to an industrial Escherichia coli fermentation

(2009) Adam L. Meadows et al.   METABOLIC ENGINEERING

Correlation between TCA cycle flux and glucose uptake rate during respiro-fermentative growth of Saccharomyces cerevisiae

(2009) J. Heyland et al.   MICROBIOLOGY-SGM