A phenome-wide association study of a lipoprotein-associated phospholipase A2loss-of-function variant in 90 000 Chinese adults

Lipoprotein-Associated Phospholipase A 2 Loss-of-Function Variant and Risk of Vascular Diseases in 90,000 Chinese Adults

(2016) Iona Y. Millwood et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Mendelian Randomization: New Applications in the Coming Age of Hypothesis-Free Causality

(2015) David M. Evans et al.   Annual Review of Genomics and Human Genetics

Coronary Heart Disease and Genetic Variants with Low Phospholipase A2 Activity

(2015) Linda M. Polfus et al.   NEW ENGLAND JOURNAL OF MEDICINE

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

Association of PLA2G7 gene polymorphisms with ischemic stroke in northern Chinese Han population

(2014) Xu Liu et al.   CLINICAL BIOCHEMISTRY

Effect of Darapladib on Major Coronary Events After an Acute Coronary Syndrome

(2014) Michelle L. O’Donoghue et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Darapladib for Preventing Ischemic Events in Stable Coronary Heart Disease

(2014)   NEW ENGLAND JOURNAL OF MEDICINE

Associations of blood glucose and prevalent diabetes with risk of cardiovascular disease in 500 000 adult Chinese: the China Kadoorie Biobank

(2013) F. Bragg et al.   DIABETIC MEDICINE

Modulation of oxidative stress, inflammation, and atherosclerosis by lipoprotein-associated phospholipase A2

(2012) Robert S. Rosenson et al.   JOURNAL OF LIPID RESEARCH

Effect of Long-Term Exposure to Lower Low-Density Lipoprotein Cholesterol Beginning Early in Life on the Risk of Coronary Heart Disease

(2012) Brian A. Ference et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

China Kadoorie Biobank of 0.5 million people: survey methods, baseline characteristics and long-term follow-up

(2011) Z. Chen et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Carriage of the V279F Null Allele within the Gene Encoding Lp-PLA2 Is Protective from Coronary Artery Disease in South Korean Males

(2011) Yangsoo Jang et al.   PLoS One

Study design and rationale for the clinical outcomes of the STABILITY Trial (STabilization of Atherosclerotic plaque By Initiation of darapLadIb TherapY) comparing darapladib versus placebo in patients with coronary heart disease

(2010) Harvey White et al.   AMERICAN HEART JOURNAL

PLA2G7 Genotype, Lipoprotein-Associated Phospholipase A 2 Activity, and Coronary Heart Disease Risk in 10 494 Cases and 15 624 Controls of European Ancestry

(2010) Juan P. Casas et al.   CIRCULATION

Lipoprotein-associated phospholipase A2 activity and mass in relation to vascular disease and nonvascular mortality

(2010)   JOURNAL OF INTERNAL MEDICINE

Lipoprotein-associated phospholipase A2 and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 prospective studies

(2010)   LANCET

Lipoprotein-associated phospholipase A2 gene V279F polymorphisms and coronary heart disease: a meta-analysis

(2010) Guo-Hua Zheng et al.   MOLECULAR BIOLOGY REPORTS

PLA2G7 gene polymorphisms and coronary heart disease risk: A meta-analysis

(2010) Qianqian Wang et al.   THROMBOSIS RESEARCH

Separating the Mechanism-Based and Off-Target Actions of Cholesteryl Ester Transfer Protein Inhibitors With CETP Gene Polymorphisms

(2009) Reecha Sofat et al.   CIRCULATION

Strengthening causal inference in cardiovascular epidemiology through Mendelian randomization

(2008) George Davey Smith et al.   ANNALS OF MEDICINE

Biology of Platelet-activating Factor Acetylhydrolase (PAF-AH, Lipoprotein Associated Phospholipase A2)

(2008) Diana M. Stafforini   CARDIOVASCULAR DRUGS AND THERAPY

Associations of PLA2G7 gene polymorphisms with plasma lipoprotein-associated phospholipase A2 activity and coronary heart disease in a Chinese Han population: the Beijing atherosclerosis study

(2008) Liping Hou et al.   HUMAN GENETICS

The Effect of Darapladib on Plasma Lipoprotein-Associated Phospholipase A2 Activity and Cardiovascular Biomarkers in Patients With Stable Coronary Heart Disease or Coronary Heart Disease Risk Equivalent

(2008) Emile R. Mohler et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY