Review
Oncology
Zhi Miao, Xiaomeng Zhao, Xuanwen Li
Summary: The purpose of this meta-analysis and systematic review was to compare the diagnostic performance of [18F]FDG PET/CT and [18F]FDG PET/MRI in colorectal liver metastasis. A total of 21 studies comprising 1036 patients were included. The results showed that [18F]FDG PET/CT and [18F]FDG PET/MRI have similar performance in detecting colorectal liver metastasis. However, larger prospective studies are needed due to limitations in the included studies.
FRONTIERS IN ONCOLOGY
(2023)
Article
Oncology
Felipe S. Furtado, Krista E. Suarez-Weiss, Mark Vangel, Jeffrey W. Clark, James C. Cusack, Theodore Hong, Lawrence Blaszkowsky, Jennifer Wo, Robin Striar, Lale Umutlu, Heike E. Daldrup-Link, David Groshar, Ricciardi Rocco, Liliana Bordeianou, Mark A. Anderson, Amirkasra Mojtahed, Motaz Qadan, Cristina Ferrone, Onofrio A. Catalano
Summary: The study suggests the potential usefulness of PET/MR in the management of oligometastatic colorectal cancer, as it has a higher diagnostic accuracy compared to standard imaging and can lead to changes in treatment strategies.
BRITISH JOURNAL OF CANCER
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Moritz L. Schnitzer, Janine Buchner, Gloria Biechele, Freba Grawe, Maria Ingenerf, Clemens G. Kaiser, Matthias F. Froelich, Christine Schmid-Tannwald, Johannes Ruebenthaler, Niklas von Muenchhausen, Wolfgang G. Kunz
Summary: This study evaluates the long-term cost-effectiveness of different imaging modalities, including MRI, PET/CT, and CE-CT, for selecting liver lesions eligible for ablation. The findings suggest that MRI is the most cost-effective strategy and should be considered as the gold standard for detecting liver metastases suitable for ablation.
EUROPEAN JOURNAL OF RADIOLOGY
(2023)
Article
Oncology
Moritz L. Schnitzer, Niklas von Muenchhausen, Gloria Biechele, Jasmin Runtemund, Freba Grawe, Thomas Geyer, Clemens G. Kaiser, Florian Haag, Johannes Ruebenthaler, Matthias F. Froelich
Summary: This study aims to assess the most economic imaging modality for detecting liver metastases eligible for hepatic resection in colorectal cancer. The results suggest that MRI is the dominant strategy.
FRONTIERS IN ONCOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Halil Komek, Canan Can, Ihsan Kaplan, Cihan Gundogan, Ferat Kepenek, Huseyin Karaoglan, Aykut Demirkiran, Senar Ebinc, Yunus Guzel, Ebubekir Gundes
Summary: [(68) Ga]Ga-DOTA-FAPI-04 PET/CT demonstrates higher sensitivity and specificity in the evaluation of primary lesions and metastases in patients with colorectal cancer.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2022)
Review
Oncology
Yang Shi, Meiqi Wang, Jiyu Zhang, Zheng Xiang, Can Li, Jingjing Zhang, Xing Ma
Summary: This review summarizes the applications of F-18-FDG PET/CT in colorectal cancer, including primary staging, follow-up assessment of tumor responses, and recurrence diagnosis. Technical considerations for PET/CT and conventional imaging modalities in newly diagnosed or treated patients with colorectal cancer are also summarized.
FRONTIERS IN ONCOLOGY
(2022)
Article
Oncology
Yue Li, Jing Gong, Xigang Shen, Menglei Li, Huan Zhang, Feng Feng, Tong Tong
Summary: This study aimed to establish and validate a machine learning-based CT radiomics model to predict metachronous liver metastasis in patients with colorectal cancer. The results showed that the fusion model combining radiomics and clinical features performed the best and could provide valuable biomarkers to identify patients with a high risk of colorectal liver metastases.
FRONTIERS IN ONCOLOGY
(2022)
Review
Medicine, Research & Experimental
Qingwei Ren, Yanyan Chen, Xuejun Shao, Lanzhong Guo, Xinxin Xu
Summary: This study aims to assess the diagnostic efficacy of 18F-FDG PET/MRI for lymph node (LN) metastasis primary staging in patients with colorectal cancer (CRC). The analysis showed that 18F-FDG PET/MRI has remarkable diagnostic performance in identifying LN metastases in newly diagnosed CRC patients, and it has great application value for the primary staging of CRC lymph node metastases.
EUROPEAN JOURNAL OF MEDICAL RESEARCH
(2023)
Review
Gastroenterology & Hepatology
Azarakhsh Baghdadi, Sahar Mirpour, Maryam Ghadimi, Mina Motaghi, Bita Hazhirkarzar, Timothy M. Pawlik, Ihab R. Kamel
Summary: Colorectal cancer metastasis to the liver is common and often treated with surgical resection, although not all patients are eligible. Imaging plays a critical role in evaluating the characteristics and treatment of CRLM, with CT being the modality of choice for diagnosis and management.
JOURNAL OF GASTROINTESTINAL SURGERY
(2022)
Review
Oncology
Raghav Chandra, John D. Karalis, Charles Liu, Gilbert Z. Murimwa, Josiah Voth Park, Christopher A. Heid, Scott I. Reznik, Emina Huang, John D. Minna, Rolf A. Brekken
Summary: Colorectal cancer (CRC) ranks as the third most common malignancy globally and the second leading cause of cancer-related deaths. The cellular components of the tumor microenvironment (TME) play crucial roles in tumor engraftment and metastasis to distant organs such as the liver and lungs.
Article
Oncology
Jianan Chen, Helen M. C. Cheung, Paul J. Karanicolas, Natalie G. Coburn, Guillaume Martel, Albert Lee, Chirag Patel, Laurent Milot, Anne L. Martel
Summary: This study proposes a radiomic model that can predict the overall survival of colorectal cancer liver metastases patients based on preoperative chemotherapy and delayed-phase contrast-enhanced MRI. The model selects robust features that are correlated with overall survival and can stratify high-risk and low-risk patients.
FRONTIERS IN ONCOLOGY
(2023)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Hasan Onner, Halil Ozer, Ahmet Volkan Celik, Farise Yilmaz, Gonca Kara Gedik
Summary: This report presents a rare case of isolated liver metastasis from prostate cancer detected by Ga-68-PSMA PET/CT. The patient had no signs of regional or distant metastases elsewhere. This highlights the importance of Ga-68-PSMA PET/CT in detecting uncommon liver metastasis from prostate cancer.
CLINICAL NUCLEAR MEDICINE
(2023)
Article
Oncology
Fanxiao Liu, Jinlei Dong, Yelong Shen, Canhua Yun, Ruixiao Wang, Ganggang Wang, Jiyang Tan, Tao Wang, Qun Yao, Bomin Wang, Lianxin Li, Jingyi Mi, Dongsheng Zhou, Fei Xiong
Summary: This study compared the utility of PET/CT and MRI in diagnosing bone metastasis in prostate cancer, showing 68Ga-PSMA PET/CT to have the highest superiority index. The diagnostic value of MRI can be enhanced by using high magnetic field strength, multisequence, DWI, and more imaging planes.
FRONTIERS IN ONCOLOGY
(2021)
Review
Radiology, Nuclear Medicine & Medical Imaging
Yong-il Kim, Hyo Sang Lee, Joon Young Choi
Summary: This study investigated the prognostic value of pre-treatment F-18-FDG PET/CT volumetric parameters for hepatic metastatic lesions in patients with CRLM. The results showed that higher MTV and TLG values for HMLs were associated with worse prognosis, indicating their potential as predictors of outcome.
CLINICAL NUCLEAR MEDICINE
(2021)
Article
Medicine, Research & Experimental
Lilang Lv, Bowen Xin, Yichao Hao, Ziyi Yang, Junyan Xu, Lisheng Wang, Xiuying Wang, Shaoli Song, Xiaomao Guo
Summary: This study developed and validated a survival model using machine learning, integrating clinico-biological features and F-18-FDG PET/CT radiomic features for predicting prognosis in colorectal cancer. The radiomics signature achieved the best result for prognostic prediction of 196 patients, while selected features accurately predicted the prognosis of 78 stage III patients. The models successfully stratified low-risk and high-risk groups, showing potential value in guiding precision treatment decisions for colorectal cancer.
JOURNAL OF TRANSLATIONAL MEDICINE
(2022)
Article
Chemistry, Physical
Eric Der, Vyacheslav Volotovskyy, Hongwei Sun, Boguslaw Tomanek, Jonathan C. Sharp
CONCEPTS IN MAGNETIC RESONANCE PART B-MAGNETIC RESONANCE ENGINEERING
(2018)
Article
Biochemical Research Methods
Hongwei Sun, Stephanie Yong, Jonathan C. Sharp
JOURNAL OF MAGNETIC RESONANCE
(2019)
Article
Radiology, Nuclear Medicine & Medical Imaging
Aaron R. Purchase, Tadeusz Palasz, Hongwei Sun, Jonathan C. Sharp, Boguslaw Tomanek
MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE
(2019)
Article
Biochemical Research Methods
Pallavi Bohidar, Hongwei Sun, Gordon E. Sarty, Jonathan C. Sharp
JOURNAL OF MAGNETIC RESONANCE
(2019)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hongwei Sun, Abbas AlZubaidi, Aaron Purchase, Jonathan C. Sharp
MAGNETIC RESONANCE IN MEDICINE
(2020)
Article
Biochemistry & Molecular Biology
Wanqi Hu, Huiting Liu, Dicheng Chen, Tianyu Qiu, Hongwei Sun, Chunyan Xiong, Jianzhong Lin, Di Guo, Hao Chen, Xiaobo Qu
Summary: Magnetic resonance spectroscopy (MRS) is a noninvasive method for molecular structure determination and metabolite detection, but its relatively low signal-to-noise ratio (SNR) limits further development. This paper proposes a novel coil-combination method to improve SNR by combining multichannel coil and repeated sampling, showing better performance compared to existing methods.
Article
Radiology, Nuclear Medicine & Medical Imaging
Zheng Zhang, Xing Chen, Qing Wan, Haiyan Wang, Na Qi, Zhiwen You, Jianmin Yuan, Lingzhi Hu, Hongwei Sun, Zhe Wang, Chenxi Hu, Jun Zhao
Summary: This study presents a two-stage cardiac PET and MR late gadolinium enhancement (LGE) co-registration method, which significantly improves image co-registration and enhances the diagnosis of non-ischemic cardiomyopathies in PET/MR imaging.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Xiangxi Meng, Hui Liu, Hui Li, Shujing Wang, Hongwei Sun, Feng Wang, Jin Ding, Liuchun He, Xin Chen, Lujia Jin, Yun Dong, Hua Zhu, Zhi Yang
Summary: The imaging ability of different positron emitters in an integrated PET/MR system was investigated, and a method for measuring PET spatial resolution in a magnetic field was proposed.
Article
Oncology
Fuquan Deng, Xiaoyuan Li, Fengjiao Yang, Hongwei Sun, Jianmin Yuan, Qiang He, Weifeng Xu, Yongfeng Yang, Dong Liang, Xin Liu, Greta S. P. Mok, Hairong Zheng, Zhanli Hu
Summary: This study used deep learning methods to perform low-dose image restoration on PSMA PET/MRI and found that synthesizing full-dose PET images based on MRI priors using 50% dose PET images did not affect the clinical diagnosis of prostate cancer. Prostate cancer patients can undergo 68Ga-PSMA prostate PET/MRI scans with radiation doses reduced by up to 50% through the use of deep learning methods to synthesize FDPET images.
FRONTIERS IN ONCOLOGY
(2022)
Article
Computer Science, Interdisciplinary Applications
Zi Wang, Chen Qian, Di Guo, Hongwei Sun, Rushuai Li, Bo Zhao, Xiaobo Qu
Summary: This study presents a new approach that utilizes 1D convolution to improve the reconstruction quality of magnetic resonance imaging. Experimental results demonstrate that this method has better reconstruction performance in the case of limited training data and exhibits good robustness to different undersampling scenarios and discrepancies between the training and test data.
IEEE TRANSACTIONS ON MEDICAL IMAGING
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Biao Qu, Xiaoyuan Li, Min Xiao, Runhan Chen, Hejuan Tan, Hongwei Sun, Rushuai Li, Jingjing Xu, Jiyang Dong, Gaofeng Zheng, Shuyue Ai, Xiaobo Qu
Summary: This study analyzed the metabolite concentrations in the putamen of Parkinson's disease (PD) patients using H-1 magnetic resonance spectroscopy (H-1-MRS). The results showed that there were no significant differences in metabolite concentrations between the bilateral putamen, but the difference in total creatine (tCr) in the left putamen might serve as a potential biomarker for distinguishing severe PD patients from healthy controls.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2023)
Article
Computer Science, Information Systems
Aaron R. Purchase, Logi Vidarsson, Keith Wachowicz, Piotr Liszkowski, Hongwei Sun, Gordon E. Sarty, Jonathan C. Sharp, Boguslaw Tomanek
Summary: Traditional Halbach magnets are widely used in MRI, but improvements in manufacturing techniques and designs are needed to reduce weight. This study successfully reduces the weight and size of Halbach magnets by optimizing the design and using high-coercivity ferromagnets, while maintaining good magnetic field homogeneity.