Transcriptomic-Based Identification of the Immuno-Oncogenic Signature of Cholangiocarcinoma for HLC-018 Multi-Target Therapy Exploration

Pharmacoinformatics and Preclinical Studies of NSC765690 and NSC765599, Potential STAT3/CDK2/4/6 Inhibitors with Antitumor Activities against NCI60 Human Tumor Cell Lines

(2021) Bashir Lawal et al.   Biomedicines

Structure-based strategies for synthesis, lead optimization and biological evaluation of N-substituted anthra[1,2-c][1,2,5]thiadiazole-6,11-dione derivatives as potential multi-target anticancer agents

(2021) Ahmed Atef Ahmed Ali et al.   Arabian Journal of Chemistry

Molecular Classification and Tumor Microenvironment Characterization of Gallbladder Cancer by Comprehensive Genomic and Transcriptomic Analysis

(2021) Nobutaka Ebata et al.   Cancers

Multi-Omics Data Analysis of Gene Expressions and Alterations, Cancer-Associated Fibroblast and Immune Infiltrations, Reveals the Onco-Immune Prognostic Relevance of STAT3/CDK2/4/6 in Human Malignancies

(2021) Bashir Lawal et al.   Cancers

mTOR/EGFR/iNOS/MAP2K1/FGFR/TGFB1 Are Druggable Candidates for N-(2,4-Difluorophenyl)-2′,4′-Difluoro-4-Hydroxybiphenyl-3-Carboxamide (NSC765598), With Consequent Anticancer Implications

(2021) Bashir Lawal et al.   Frontiers in Oncology

Identification of Cancer Hub Gene Signatures Associated with Immune-Suppressive Tumor Microenvironment and Ovatodiolide as a Potential Cancer Immunotherapeutic Agent

(2021) Jia-Hong Chen et al.   Cancers

Multiomics Identification of Potential Targets for Alzheimer Disease and Antrocin as a Therapeutic Candidate

(2021) Alexander T. H. Wu et al.   Pharmaceutics

Large-scale public data reuse to model immunotherapy response and resistance

(2020) Jingxin Fu et al.   Genome Medicine

Identification of novel methylation markers in HPV-associated oropharyngeal cancer: genome-wide discovery, tissue verification and validation testing in ctDNA

(2020) Kiyoshi Misawa et al.   ONCOGENE

Preclinical Evaluation of the Novel Small-Molecule MSI-N1014 for Treating Drug-Resistant Colon Cancer via the LGR5/β-catenin/miR-142-3p Network and Reducing Cancer-Associated Fibroblast Transformation

(2020) Vijesh Kumar Yadav et al.   Cancers

Identification of the Effects of Aspirin and Sulindac Sulfide on the Inhibition of HMGA2-Mediated Oncogenic Capacities in Colorectal Cancer

(2020) Titus Ime Ekanem et al.   MOLECULES

Immunotherapy in Biliary Tract Cancer: Worthy of a Second Look

(2020) Angela Dalia Ricci et al.   Cancer Control

Recent advances of immunotherapy for biliary tract cancer

(2020) Alessandro Rizzo et al.   Expert Review of Gastroenterology & Hepatology

HNC0014, a Multi-Targeted Small-Molecule, Inhibits Head and Neck Squamous Cell Carcinoma by Suppressing c-Met/STAT3/CD44/PD-L1 Oncoimmune Signature and Eliciting Antitumor Immune Responses

(2020) Jih-Chin Lee et al.   Cancers

Oncological role of HMGA2 (Review)

(2019) Shizhen Zhang et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

GSCALite: a web server for gene set cancer analysis

(2018) Chun-Jie Liu et al.   BIOINFORMATICS

Niclosamide, a Drug with Many (Re)purposes

(2018) Hachemi Kadri et al.   ChemMedChem

Arthroprotective Effects of Cf-02 Sharing Structural Similarity with Quercetin

(2018) Feng-Cheng Liu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

miRNA‑26a‑5p and miR‑26b‑5p inhibit the proliferation of bladder cancer cells by regulating PDCD10

(2018) Ke Wu et al.   ONCOLOGY REPORTS

Detection of Malignancy‐Associated Phosphoproteome Changes in Human Colorectal Cancer Induced by Cell Surface Binding of Growth‐Inhibitory Galectin‐4

(2018) Malwina Michalak et al.   IUBMB LIFE

TRIM59 promotes breast cancer motility by suppressing p62-selective autophagic degradation of PDCD10

(2018) Peng Tan et al.   PLOS BIOLOGY

BET inhibitors in metastatic prostate cancer: therapeutic implications and rational drug combinations

(2017) Mark C. Markowski et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Cholangiocarcinoma — evolving concepts and therapeutic strategies

(2017) Sumera Rizvi et al.   Nature Reviews Clinical Oncology

UALCAN: A Portal for Facilitating Tumor Subgroup Gene Expression and Survival Analyses

(2017) Darshan S. Chandrashekar et al.   NEOPLASIA

Risk factors for intrahepatic and extrahepatic cholangiocarcinoma in the United States: A population-based study in SEER-Medicare

(2017) Jessica L. Petrick et al.   PLoS One

Assessing the Growth of Bioactive Compounds and Scaffolds over Time: Implications for Lead Discovery and Scaffold Hopping

(2016) Swarit Jasial et al.   Journal of Chemical Information and Modeling

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

MicroRNA-103 suppresses tumor cell proliferation by targetingPDCD10in prostate cancer

(2016) Xiaoliang Fu et al.   PROSTATE

TC-N19, a novel dual inhibitor of EGFR and cMET, efficiently overcomes EGFR-TKI resistance in non-small-cell lung cancer cells

(2016) D-W Wu et al.   Cell Death & Disease

Design, synthesis and biological evaluation of tetracyclic azafluorenone derivatives with topoisomerase I inhibitory properties as potential anticancer agents

(2016) Tsung-Chih Chen et al.   Arabian Journal of Chemistry

Predictability of Genetic Interactions from Functional Gene Modules

(2016) Jonathan H. Young et al.   G3-Genes Genomes Genetics

Role of SNARE proteins in tumourigenesis and their potential as targets for novel anti-cancer therapeutics

(2015) Jianghui Meng et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Novel inhibitors of RANKL-induced osteoclastogenesis: Design, synthesis, and biological evaluation of 6-(2,4-difluorophenyl)-3-phenyl-2H-benzo[e][1,3]oxazine-2,4(3H)-diones

(2015) Chia-Chung Lee et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Discovery of 5-(2′,4′-difluorophenyl)-salicylanilides as new inhibitors of receptor activator of NF-κB ligand (RANKL)-induced osteoclastogenesis

(2015) Chia-Chung Lee et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Structure-based hybridization, synthesis and biological evaluation of novel tetracyclic heterocyclic azathioxanthone analogues as potential antitumor agents

(2015) Tsung-Chih Chen et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

PLIP: fully automated protein–ligand interaction profiler

(2015) Sebastian Salentin et al.   NUCLEIC ACIDS RESEARCH

Identification of Gene Expression Pattern Related to Breast Cancer Survival Using Integrated TCGA Datasets and Genomic Tools

(2015) Zhenzhen Huang et al.   Biomed Research International

Multi-targeted therapy of cancer by niclosamide: A new application for an old drug

(2014) Yonghe Li et al.   CANCER LETTERS

Cholangiocarcinoma

(2014) Nataliya Razumilava et al.   LANCET

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

(2013) Edward Y Chen et al.   BMC BIOINFORMATICS

HMGA2 Is a Driver of Tumor Metastasis

(2013) A. Morishita et al.   CANCER RESEARCH

Pathogenesis, Diagnosis, and Management of Cholangiocarcinoma

(2013) Sumera Rizvi et al.   GASTROENTEROLOGY

High HMGA2 expression and high body mass index negatively affect the prognosis of patients with ovarian cancer

(2013) Daniela Califano et al.   JOURNAL OF CELLULAR PHYSIOLOGY

SurvExpress: An Online Biomarker Validation Tool and Database for Cancer Gene Expression Data Using Survival Analysis

(2013) Raul Aguirre-Gamboa et al.   PLoS One

A Benzamide-linked Small Molecule NDMC101 Inhibits NFATc1 and NF-κB Activity: A Potential Osteoclastogenesis Inhibitor for Experimental Arthritis

(2012) Chia-Pi Cheng et al.   JOURNAL OF CLINICAL IMMUNOLOGY

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Avogadro: an advanced semantic chemical editor, visualization, and analysis platform

(2012) Marcus D Hanwell et al.   Journal of Cheminformatics

Clinical diagnosis and staging of cholangiocarcinoma

(2011) Boris Blechacz et al.   Nature Reviews Gastroenterology & Hepatology

Transcriptomic signature of cell lines isolated from canine mammary adenocarcinoma metastases to lungs

(2010) M. Król et al.   JOURNAL OF APPLIED GENETICS

Synthesis, cytotoxicity and human telomerase inhibition activities of a series of 1,2-heteroannelated anthraquinones and anthra[1,2-d]imidazole-6,11-dione homologues

(2009) Hsu-Shan Huang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

(2009) Oleg Trott et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

GeneMANIA: a real-time multiple association network integration algorithm for predicting gene function

(2008) Sara Mostafavi et al.   GENOME BIOLOGY