Zscan4 Contributes to Telomere Maintenance in Telomerase-Deficient Late Generation Mouse ESCs and Human ALT Cancer Cells

TERRA transcription destabilizes telomere integrity to initiate break-induced replication in human ALT cells

(2021) Bruno Silva et al.   Nature Communications

Zscan4 binds nucleosomal microsatellite DNA and protects mouse two-cell embryos from DNA damage

(2020) Rajini Srinivasan et al.   Science Advances

ZSCAN4 facilitates chromatin remodeling and promotes the cancer stem cell phenotype

(2020) Benjamin A. Portney et al.   ONCOGENE

Dcaf11 activates Zscan4-mediated alternative telomere lengthening in early embryos and embryonic stem cells

(2020) Rongrong Le et al.   Cell Stem Cell

TRF2-mediated telomere protection is dispensable in pluripotent stem cells

(2020) Marta Markiewicz-Potoczny et al.   NATURE

Alternative Lengthening of Telomeres through Two Distinct Break-Induced Replication Pathways

(2019) Jia-Min Zhang et al.   Cell Reports

RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres

(2019) Jonathan Barroso-González et al.   MOLECULAR CELL

SLX4IP Antagonizes Promiscuous BLM Activity during ALT Maintenance

(2019) Stephanie Panier et al.   MOLECULAR CELL

Alternative Lengthening of Telomeres Mediated by Mitotic DNA Synthesis Engages Break-Induced Replication Processes

(2017) Jaewon Min et al.   MOLECULAR AND CELLULAR BIOLOGY

DUX-family transcription factors regulate zygotic genome activation in placental mammals

(2017) Alberto De Iaco et al.   NATURE GENETICS

Conserved roles of mouse DUX and human DUX4 in activating cleavage-stage genes and MERVL/HERVL retrotransposons

(2017) Peter G Hendrickson et al.   NATURE GENETICS

Conservation and innovation in the DUX4-family gene network

(2017) Jennifer L Whiddon et al.   NATURE GENETICS

Zscan4 Inhibits Maintenance DNA Methylation to Facilitate Telomere Elongation in Mouse Embryonic Stem Cells

(2017) Jiameng Dan et al.   Cell Reports

Alternative lengthening of human telomeres is a conservative DNA replication process with features of break‐induced replication

(2016) Fani‐Marlen Roumelioti et al.   EMBO REPORTS

Break-induced telomere synthesis underlies alternative telomere maintenance

(2016) Robert L. Dilley et al.   NATURE

MERVL/Zscan4 Network Activation Results in Transient Genome-wide DNA Demethylation of mESCs

(2016) Mélanie A. Eckersley-Maslin et al.   Cell Reports

Zscan4 Is Activated after Telomere Shortening in Mouse Embryonic Stem Cells

(2016) Yoko Nakai-Futatsugi et al.   Stem Cell Reports

Rif1 Maintains Telomere Length Homeostasis of ESCs by Mediating Heterochromatin Silencing

(2014) Jiameng Dan et al.   DEVELOPMENTAL CELL

Short Telomeres in ESCs Lead to Unstable Differentiation

(2013) Fabio Pucci et al.   Cell Stem Cell

Robust measurement of telomere length in single cells

(2013) F. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Roles for Tbx3 in regulation of two-cell state and telomere elongation in mouse ES cells

(2013) Jiameng Dan et al.   Scientific Reports

Antitelomerase Therapy Provokes ALT and Mitochondrial Adaptive Mechanisms in Cancer

(2012) Jian Hu et al.   CELL

Chromatin organization is a major influence on regional mutation rates in human cancer cells

(2012) Benjamin Schuster-Böckler et al.   NATURE

Embryonic stem cell potency fluctuates with endogenous retrovirus activity

(2012) Todd S. Macfarlan et al.   NATURE

Telomere length regulates TERRA levels through increased trimethylation of telomeric H3K9 and HP1α

(2012) Nausica Arnoult et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cancer and Telomeres--An ALTernative to Telomerase

(2012) J. W. Shay et al.   SCIENCE

Molecular insights into the heterogeneity of telomere reprogramming in induced pluripotent stem cells

(2011) Fang Wang et al.   CELL RESEARCH

Association of telomere length with authentic pluripotency of ES/iPS cells

(2011) Junjiu Huang et al.   CELL RESEARCH

Different telomere-length dynamics at the inner cell mass versus established embryonic stem (ES) cells

(2011) E. Varela et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Zscan4 regulates telomere elongation and genomic stability in ES cells

(2010) Michal Zalzman et al.   NATURE

Epigenetic regulation of telomere chromatin integrity in pluripotent embryonic stem cells

(2010) Lee H Wong   Epigenomics

Telomeres Acquire Embryonic Stem Cell Characteristics in Induced Pluripotent Stem Cells

(2009) Rosa M. Marion et al.   Cell Stem Cell

Probing PML body function in ALT cells reveals spatiotemporal requirements for telomere recombination

(2009) I. Draskovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How Shelterin Protects Mammalian Telomeres

(2008) Wilhelm Palm et al.   Annual Review of Genetics

Epigenetic regulation of telomeres in human cancer

(2008) E Vera et al.   ONCOGENE

Alternative lengthening of telomeres (ALT) and chromatin: Is there a connection?

(2007) Thalia Nittis et al.   BIOCHIMIE

Telomeric position effect: From the yeast paradigm to human pathologies?

(2007) Alexandre Ottaviani et al.   BIOCHIMIE