Article
Clinical Neurology
Glenn Phillips, Catarina Abreu, Amit Goyal, Yuebing Li, Albert Whangbo, Deborah Gelinas, Edward Brauer, Sankha Bhattacharya
Summary: This study investigated healthcare resource utilization and associated costs for adults with generalized myasthenia gravis (gMG) in the United States. The results showed that newly diagnosed patients had higher healthcare resource utilization and costs compared to previously diagnosed patients, and costs further increased for patients with exacerbation events. For patients who experienced crisis events, costs significantly increased during the 12 months before the event and further increased in the 12 months following the event. The high costs were largely attributed to the treatments received.
FRONTIERS IN NEUROLOGY
(2022)
Article
Public, Environmental & Occupational Health
Yingyan Ma, Yuechun Wen, Hua Zhong, Senlin Lin, Li Liang, Yifang Yang, Huifen Jiang, Jian Chen, Yan Huang, Xiaohua Ying, Serge Resnikoff, Lina Lu, Jianfeng Zhu, Xun Xu, Xiangui He, Haidong Zou
Summary: This study investigates the utilization of various correction methods and health service for myopia in urban China and estimates the costs of treatment, prevention, and productivity loss. The findings reveal that myopia poses a substantial economic burden in China.
JOURNAL OF GLOBAL HEALTH
(2022)
Article
Obstetrics & Gynecology
Leslie Farland, Judy E. Stern, Chia-ling Liu, Howard J. Cabral, Charles C. Coddington, Hafsatou Diop, Dmitry Dukhovny, Sunah Hwang, Stacey A. Missmer
Summary: Women with a history of endometriosis or fibroids have a higher risk of pregnancy complications and preterm birth. This risk is increased when they have a history of infertility or utilize assisted reproductive technology.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2022)
Article
Clinical Neurology
K. Heerlein, S. De Giorgi, G. Degraeve, T. Frodl, W. Hagedoorn, A. J. Oliveira-Maia, C. Otte, V Perez Sola, S. Rathod, G. Rosso, P. Sierra, A. Vita, J. Morrens, B. Rive, S. Mulhern Haughey, Y. Kambarov, A. H. Young
Summary: Research found that patients with treatment resistant depression (TRD) have higher healthcare resource utilization compared to other depression patients, especially those who do not achieve remission. Economically, the impact of non-responders and non-remitters is significantly greater than that of responders and remitters.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Oncology
Devon K. Check, Bradford E. Jackson, Katherine E. Reeder-Hayes, Michaela A. Dinan, Eleanor Faherty, Jackie Kwong, Sandhya Mehta, Lisa Spees, Stephanie B. Wheeler, Lauren E. Wilson, Clara Lam
Summary: The prevalence of HER2-low breast cancer is high, representing more than half of the overall and stage IV patient cohorts. HER2-low patients are more likely to have hormone receptor-positive disease and be Black in the stage IV cohort. Rates of hospitalizations are slightly higher among HER2-low patients, but there are no survival differences compared to IHC 0 patients in the stage IV cohort.
BREAST CANCER RESEARCH AND TREATMENT
(2023)
Article
Gastroenterology & Hepatology
Hsiu-Ting Chien, Tung-Hung Su, Hazel Huang, Chih-Lin Chiang, Fang-Ju Lin
Summary: This study provides updated epidemiology, clinical, and economic outcomes of patients diagnosed with chronic hepatitis B in Taiwan. The prevalence of diagnosed CHB has increased over the years, particularly among men aged 55-64 years and 45-54 years. Most newly diagnosed patients were 35 years of age or older. In terms of treatment, the majority of patients received entecavir.
LIVER INTERNATIONAL
(2023)
Article
Immunology
Kamila Romanowski, Michael R. Law, Mohammad Ehsanul Karim, Jonathon R. Campbell, Md Belal Hossain, Mark Gilbert, Victoria J. Cook, James C. Johnston
Summary: A study found that people treated for respiratory tuberculosis experience increased healthcare utilization in the years following treatment, with respiratory morbidity being a significant contributor. This highlights the importance of screening, assessment, and treatment for post-tuberculosis sequelae.
CLINICAL INFECTIOUS DISEASES
(2023)
Review
Rheumatology
Leonardo Martin Calderon, Mitali Chaudhury, Janet E. Pope
Summary: This study provides a systematic review of the economic impact and healthcare resource utilization associated with systemic sclerosis (SSc). The findings indicate that SSc poses a significant economic burden on patients and healthcare resources, with the burden increasing with SSc-associated complications and varying depending on geographical location and access to healthcare resources.
Article
Allergy
William McCann, Steven L. Hass, Kevin Norrett, Ann Cameron, Martine Etschmaier, Amy Duhig, Shengsheng Yu
Summary: The study revealed that patients with peanut allergies and their caregivers utilized healthcare resources frequently in the past year, experiencing significant impacts on household work, schoolwork, and employed work. Additionally, peanut allergies affected school attendance of children with PA. New treatments to prevent or lower the risk of PA reactions could help reduce healthcare resource utilization and productivity loss associated with PA.
WORLD ALLERGY ORGANIZATION JOURNAL
(2021)
Article
Multidisciplinary Sciences
Giovanni Antonini, Francesco Habetswallner, Maurizio Inghilleri, Renato Mantegazza, Carmelo Rodolico, Francesco Sacca, Manlio Sgarzi, Femke deRuyck, Sandra Paci, Glenn Phillips, Laura Crippa, Chiara Veronesi, Valentina Perrone, Luca Degli Esposti
Summary: The purpose of this study was to investigate the epidemiology, management, and economic burden of myasthenia gravis in real clinical practice. The estimated prevalence of myasthenia gravis in Italy during 2018 was in the range of 13.5-29.3/100,000 people, with a large number of patients using pyridostigmine and corticosteroids for treatment. The total healthcare costs for myasthenia gravis were significantly higher than those of the general population, especially for patients with exacerbation.
Article
Medicine, Research & Experimental
Clara Weil, Philip B. Sugerman, Gabriel Chodick, Huifang Liang, Hongwei Wang, Brian M. Calimlim, Ana Dorfman, Varda Shalev, Dan Ben Amitai, Yael A. Leshem
Summary: This study describes the prevalence and economic burden of atopic dermatitis in Israel using data from a healthcare provider. The incidence of atopic dermatitis was 7.0 per 1000 person-years, and the overall prevalence was 4.4%, with 42.3% suggestive of moderate to severe disease. Patients with atopic dermatitis had higher healthcare service utilization and costs compared to those without the condition.
ADVANCES IN THERAPY
(2022)
Article
Obstetrics & Gynecology
Khaoula Ben Messaoud, Jean Bouyer, Juliette Guibert, Elise de la Rochebrochard
Summary: Despite free treatment, almost one in four women had a very early dropout following unsuccessful clomiphene citrate (CC)/gonadotropin treatment, with patients below the poverty line being more likely to drop out early.
HUMAN REPRODUCTION
(2023)
Article
Medicine, General & Internal
Mohammad Azmain Iktidar, Sreshtha Chowdhury, Simanta Roy, A. M. Khairul Islam, Mahzabeen Islam, Tonmoy Chowdhury, Mustari Nailah Tabassum, Tahsin Sumat Ali, Atandra Akash, Mashrur Ahmed, Faraz Al Zafar, Mohammad Delwer Hossain Hawlader
Summary: This study found that medical students and healthcare professionals in Bangladesh have inadequate knowledge and negative attitudes regarding male infertility despite favorable opinions. Young healthcare professionals and medical students, as well as women, were more likely to have good knowledge and positive attitudes. Bachelor of Medicine and Surgery doctors were most likely to have good knowledge and positive attitudes regarding male infertility. Good knowledge predicted positive attitudes, and vice versa.
Article
Gastroenterology & Hepatology
Naama Yekutiel, Gabriel Chodick, Jana Knop, Taner Cavlar, Sveta Tsukinovsky, Ginat Toren, Revital Kariv
Summary: This study describes the epidemiology of gastroparesis and estimates the short-term healthcare resource use burden of gastroparesis in a large population. The results show that gastroparesis patients are more likely to have cardiovascular diseases, lower BMI, and require more healthcare resource utilization.
NEUROGASTROENTEROLOGY AND MOTILITY
(2023)
Article
Health Care Sciences & Services
Jingchun Liu, Wuyue Han, Haoyu Wang, Zhi Wang, Bingshu Li, Li Hong
Summary: The burden of endometriosis-related infertility has shown a weak declining trend globally, but varies considerably across regions, age groups, periods, and birth cohorts.
JOURNAL OF PERSONALIZED MEDICINE
(2023)