HIV-1 propagation is highly dependent on basal levels of the restriction factor BST2

Loss of tetherin antagonism by Nef impairs SIV replication during acute infection of rhesus macaques

(2020) Aidin Tavakoli-Tameh et al.   PLoS Pathogens

Mutations in the HIV-1 envelope glycoprotein can broadly rescue blocks at multiple steps in the virus replication cycle

(2019) Rachel Van Duyne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Potent Enhancement of HIV-1 Replication by Nef in the Absence of SERINC3 and SERINC5

(2019) Yuanfei Wu et al.   mBio

HIV-1 gag recruits PACSIN2 to promote virus spreading

(2018) Sergei Popov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BST-2 Expression Modulates Small CD4-Mimetic Sensitization of HIV-1-Infected Cells to Antibody-Dependent Cellular Cytotoxicity

(2017) Jonathan Richard et al.   JOURNAL OF VIROLOGY

Tetherin/BST-2: Restriction Factor or Immunomodulator?

(2016) Sam X. Li et al.   CURRENT HIV RESEARCH

Tetherin Antagonism by HIV-1 Group M Nef Proteins

(2016) Juan F. Arias et al.   JOURNAL OF VIROLOGY

Vpu-Mediated Counteraction of Tetherin Is a Major Determinant of HIV-1 Interferon Resistance

(2016) Dorota Kmiec et al.   mBio

Enhancing Virion Tethering by BST2 Sensitizes Productively and Latently HIV-infected T cells to ADCC Mediated by Broadly Neutralizing Antibodies

(2016) Tram N. Q. Pham et al.   Scientific Reports

SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef

(2015) Yoshiko Usami et al.   NATURE

Tethering Viral Restriction to Signal Transduction

(2014) Juan F. Arias et al.   Cell Host & Microbe

Tetherin Promotes the Innate and Adaptive Cell-Mediated Immune Response against Retrovirus Infection In Vivo

(2014) S. X. Li et al.   JOURNAL OF IMMUNOLOGY

Differential Sensitivities of Tetherin Isoforms to Counteraction by Primate Lentiviruses

(2014) J. Weinelt et al.   JOURNAL OF VIROLOGY

HIV-1 Vpu Antagonism of Tetherin Inhibits Antibody-Dependent Cellular Cytotoxic Responses by Natural Killer Cells

(2014) R. A. Alvarez et al.   JOURNAL OF VIROLOGY

Tetherin antagonism by Vpu protects HIV-infected cells from antibody-dependent cell-mediated cytotoxicity

(2014) J. F. Arias et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIV Nef and Vpu protect HIV-infected CD4+ T cells from antibody-mediated cell lysis through down-modulation of CD4 and BST2

(2014) Tram NQ Pham et al.   Retrovirology

HIV-1-induced AIDS in monkeys

(2014) T. Hatziioannou et al.   SCIENCE

Cell-to-Cell Transmission Can Overcome Multiple Donor and Target Cell Barriers Imposed on Cell-Free HIV

(2013) Peng Zhong et al.   PLoS One

Innate Sensing of HIV-1 Assembly by Tetherin Induces NFκB-Dependent Proinflammatory Responses

(2012) Rui Pedro Galão et al.   Cell Host & Microbe

Reacquisition of Nef-Mediated Tetherin Antagonism in a Single In Vivo Passage of HIV-1 through Its Original Chimpanzee Host

(2012) Nicola Götz et al.   Cell Host & Microbe

Cutting Edge: Paradoxical Roles of BST2/Tetherin in Promoting Type I IFN Response and Viral Infection

(2012) M. Swiecki et al.   JOURNAL OF IMMUNOLOGY

Stimulation of NF- B Activity by the HIV Restriction Factor BST2

(2012) A. Tokarev et al.   JOURNAL OF VIROLOGY

Identification of Alternatively Translated Tetherin Isoforms with Differing Antiviral and Signaling Activities

(2012) Luis J. Cocka et al.   PLoS Pathogens

Compensatory Changes in the Cytoplasmic Tail of gp41 Confer Resistance to Tetherin/BST-2 in a Pathogenic Nef-Deleted SIV

(2011) Ruth Serra-Moreno et al.   Cell Host & Microbe

Assembly and Replication of HIV-1 in T Cells with Low Levels of Phosphatidylinositol-(4,5)-Bisphosphate

(2011) K. Monde et al.   JOURNAL OF VIROLOGY

Tetherin is a key effector of the antiretroviral activity of type I interferon in vitro and in vivo

(2011) R. A. Liberatore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SIV Nef Proteins Recruit the AP-2 Complex to Antagonize Tetherin and Facilitate Virion Release

(2011) Fengwen Zhang et al.   PLoS Pathogens

The Interferon-Inducible Host Factor Bone Marrow Stromal Antigen 2/Tetherin Restricts Virion Release, but Is It Actually a Viral Restriction Factor?

(2010) Amy Andrew et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Cell-Cell Spread of Human Immunodeficiency Virus Type 1 Overcomes Tetherin/BST-2-Mediated Restriction in T cells

(2010) C. Jolly et al.   JOURNAL OF VIROLOGY

MLV glycosylated-Gag is an infectivity factor that rescues Nef-deficient HIV-1

(2010) M. Pizzato   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct Restriction of Virus Release and Incorporation of the Interferon-Induced Protein BST-2 into HIV-1 Particles

(2010) Kathleen Fitzpatrick et al.   PLoS Pathogens

Antiviral Activity of the Interferon-Induced Cellular Protein BST-2/Tetherin

(2009) Andrey Tokarev et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Tetherin Inhibits HIV-1 Release by Directly Tethering Virions to Cells

(2009) David Perez-Caballero et al.   CELL

Nef Proteins from Simian Immunodeficiency Viruses Are Tetherin Antagonists

(2009) Fengwen Zhang et al.   Cell Host & Microbe

Tetherin-Driven Adaptation of Vpu and Nef Function and the Evolution of Pandemic and Nonpandemic HIV-1 Strains

(2009) Daniel Sauter et al.   Cell Host & Microbe

Species-Specific Activity of SIV Nef and HIV-1 Vpu in Overcoming Restriction by Tetherin/BST2

(2009) Bin Jia et al.   PLoS Pathogens

The Interferon-Induced Protein BST-2 Restricts HIV-1 Release and Is Downregulated from the Cell Surface by the Viral Vpu Protein

(2008) Nanette Van Damme et al.   Cell Host & Microbe

Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu

(2008) Stuart J. D. Neil et al.   NATURE