Selenoprotein K deficiency-induced apoptosis: A role for calpain and the ERS pathway

A trio has turned into a quartet: DJ-1 interacts with the IP3R-Grp75-VDAC complex to control ER-mitochondria interaction

(2020) Valentina Basso et al.   CELL CALCIUM

PI3‐kinase/Akt pathway‐regulated membrane transportation of acid‐sensing ion channel 1a/Calcium ion influx/endoplasmic reticulum stress activation on PDGF‐induced HSC Activation

(2019) Longquan Zuo et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Apathy and anxiety are early markers of Alzheimer's disease

(2019) Maurits Johansson et al.   NEUROBIOLOGY OF AGING

Selenoprotein K deficiency inhibits melanoma by reducing calcium flux required for tumor growth and metastasis

(2018) Michael P. Marciel et al.   Oncotarget

IRE1α siRNA relieves endoplasmic reticulum stress-induced apoptosis and alleviates diabetic peripheral neuropathy in vivo and in vitro

(2018) Weijie Yao et al.   Scientific Reports

Transglutaminase Type 2 Regulates ER-Mitochondria Contact Sites by Interacting with GRP75

(2018) Manuela D’Eletto et al.   Cell Reports

4PBA strongly attenuates endoplasmic reticulum stress, fibrosis, and mitochondrial apoptosis markers in cyclosporine treated human gingival fibroblasts

(2017) Suresh Ranga Rao et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Selenomethionine Mitigates Cognitive Decline by Targeting Both Tau Hyperphosphorylation and Autophagic Clearance in an Alzheimer's Disease Mouse Model

(2017) Zhong-Hao Zhang et al.   JOURNAL OF NEUROSCIENCE

Can ‘calpain-cathepsin hypothesis’ explain Alzheimer neuronal death?

(2016) Tetsumori Yamashima   AGEING RESEARCH REVIEWS

A Novel Aβ B-Cell Epitope Vaccine (rCV01) for Alzheimer’s Disease Improved Synaptic and Cognitive Functions in 3 × Tg-AD Mice

(2016) Yun-Zhou Yu et al.   Journal of Neuroimmune Pharmacology

Cysteine Sulfenylation Directs IRE-1 to Activate the SKN-1/Nrf2 Antioxidant Response

(2016) John M. Hourihan et al.   MOLECULAR CELL

Selenoprotein K and Protein Palmitoylation

(2015) Gregory J. Fredericks et al.   ANTIOXIDANTS & REDOX SIGNALING

Membrane-Bound Selenoproteins

(2015) Jun Liu et al.   ANTIOXIDANTS & REDOX SIGNALING

Selenoprotein S-dependent Selenoprotein K Binding to p97(VCP) Protein Is Essential for Endoplasmic Reticulum-associated Degradation

(2015) Jea Hwang Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

4-Phenylbutyrate protects rat skin flaps against ischemia-reperfusion injury and apoptosis by inhibiting endoplasmic reticulum stress

(2015) ZHEN-SHUANG YUE et al.   Molecular Medicine Reports

Asbestos-induced Disruption of Calcium Homeostasis Induces Endoplasmic Reticulum Stress in Macrophages

(2014) Alan J. Ryan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stable expression and function of the inositol 1,4,5-triphosphate receptor requires palmitoylation by a DHHC6/selenoprotein K complex

(2014) Gregory J. Fredericks et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endoplasmic Reticulum Stress Sensing in the Unfolded Protein Response

(2013) B. M. Gardner et al.   Cold Spring Harbor Perspectives in Biology

Selenoprotein K Binds Multiprotein Complexes and Is Involved in the Regulation of Endoplasmic Reticulum Homeostasis

(2011) Valentina A. Shchedrina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selenoprotein K Knockout Mice Exhibit Deficient Calcium Flux in Immune Cells and Impaired Immune Responses

(2011) S. Verma et al.   JOURNAL OF IMMUNOLOGY

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

(2011) Ira Tabas et al.   NATURE CELL BIOLOGY

Road to Ruin: Targeting Proteins for Degradation in the Endoplasmic Reticulum

(2011) M. H. Smith et al.   SCIENCE

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

SelK is a novel ER stress-regulated protein and protects HepG2 cells from ER stress agent-induced apoptosis

(2010) Shaoqing Du et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Dietary Selenium Modulates Activation and Differentiation of CD4+ T Cells in Mice through a Mechanism Involving Cellular Free Thiols

(2010) FuKun W. Hoffmann et al.   JOURNAL OF NUTRITION