Recent Advances in Bedside Device-Based Early Detection of Sepsis

Simultaneous electrical detection of IL-6 and PCT using a microfluidic biochip platform

(2020) Jacob Berger et al.   BIOMEDICAL MICRODEVICES

Evaluation of TNF-α genetic polymorphisms as predictors for sepsis susceptibility and progression

(2020) Anca Meda Georgescu et al.   BMC INFECTIOUS DISEASES

Complement in sepsis—when science meets clinics

(2020) Tom E. Mollnes et al.   FEBS LETTERS

Disposable Paper-on-CMOS Platform for Real-Time Simultaneous Detection of Metabolites

(2020) Chunxiao Hu et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Serum citrullinated histone H3 concentrations differentiate patients with septic verses non-septic shock and correlate with disease severity

(2020) Yuzi Tian et al.   INFECTION

Identification and Quantitative Determination of Lactate Using Optical Spectroscopy—Towards a Noninvasive Tool for Early Recognition of Sepsis

(2020) Karthik Budidha et al.   SENSORS

Sepsis Alerts in Emergency Departments: A Systematic Review of Accuracy and Quality Measure Impact

(2020) Matthew Hwang et al.   Western Journal of Emergency Medicine

Cutting-Edge Technology for Rapid Bedside Assessment of Capillary Refill Time for Early Diagnosis and Resuscitation of Sepsis

(2020) David C. Sheridan et al.   Frontiers in Medicine

CTLA-4 Genetic Variants Predict Survival in Patients with Sepsis

(2019) Caspar Mewes et al.   Journal of Clinical Medicine

Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock

(2019) Glenn Hernández et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

CRP-guided Antibiotic Treatment in acute exacerbations of COPD admitted to Hospital

(2019) H. J. Prins et al.   EUROPEAN RESPIRATORY JOURNAL

Is Interleukin-6 a better predictor of successful antibiotic therapy than procalcitonin and C-reactive protein? A single center study in critically ill adults

(2019) Lorenz Weidhase et al.   BMC INFECTIOUS DISEASES

Early sepsis diagnosis via protein and miRNA biomarkers using a novel point-of-care photonic biosensor

(2019) Nuria Fabri-Faja et al.   ANALYTICA CHIMICA ACTA

Epidemiology of Hospital-Onset Versus Community-Onset Sepsis in U.S. Hospitals and Association With Mortality

(2019) Chanu Rhee et al.   CRITICAL CARE MEDICINE

Patient Outcomes and Cost-Effectiveness of a Sepsis Care Quality Improvement Program in a Health System

(2019) Majid Afshar et al.   CRITICAL CARE MEDICINE

C-Reactive Protein Testing to Guide Antibiotic Prescribing for COPD Exacerbations

(2019) Christopher C. Butler et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients with Septic Shock: A Bayesian Reanalysis of the ANDROMEDA-SHOCK Trial

(2019) Fernando G Zampieri et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A case-control study on the relationship between miRNAs single nucleotide polymorphisms and sepsis risk

(2019) Yan Zhang et al.   MEDICINE

An Integrated Plasmo‐Photoelectronic Nanostructure Biosensor Detects an Infection Biomarker Accompanying Cell Death in Neutrophils

(2019) Younggeun Park et al.   Small

Integrated Biosensor for Rapid and Point-of-Care Sepsis Diagnosis

(2018) Jouha Min et al.   ACS Nano

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016

(2017) Andrew Rhodes et al.   INTENSIVE CARE MEDICINE

Prognostic Accuracy of the SOFA Score, SIRS Criteria, and qSOFA Score for In-Hospital Mortality Among Adults With Suspected Infection Admitted to the Intensive Care Unit

(2017) Eamon P. Raith et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Incidence and Trends of Sepsis in US Hospitals Using Clinical vs Claims Data, 2009-2014

(2017) Chanu Rhee et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Variability of Capillary Refill Time among Physician Measurements

(2017) David C. Sheridan et al.   JOURNAL OF EMERGENCY MEDICINE

Cytokine storm and sepsis disease pathogenesis

(2017) Benjamin G. Chousterman et al.   Seminars in Immunopathology

A point-of-care microfluidic biochip for quantification of CD64 expression from whole blood for sepsis stratification

(2017) U. Hassan et al.   Nature Communications

Capillary refill time during fluid resuscitation in patients with sepsis-related hyperlactatemia at the emergency department is related to mortality

(2017) Barbara Lara et al.   PLoS One

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

(2016) Mervyn Singer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Delayed Recognition of Deterioration of Patients in General Wards Is Mostly Caused by Human Related Monitoring Failures: A Root Cause Analysis of Unplanned ICU Admissions

(2016) Louise S. van Galen et al.   PLoS One

The coagulopathy of acute sepsis

(2015) Jeff Simmons et al.   Current Opinion in Anesthesiology

Diagnostic accuracy and effectiveness of automated electronic sepsis alert systems: A systematic review

(2015) Anil N. Makam et al.   Journal of Hospital Medicine

A pilot study of quantitative capillary refill time to identify high blood lactate levels in critically ill patients

(2014) Naoto Morimura et al.   EMERGENCY MEDICINE JOURNAL

Normal Ranges for Acute Phase Reactants (Interleukin-6, Tumour Necrosis Factor Alpha and C-Reactive Protein) in Umbilical Cord Blood of Healthy Term Neonates at the Mount Hope Women’s Hospital Trinidad

(2014) A Khan et al.   WEST INDIAN MEDICAL JOURNAL

Biomarkers of sepsis

(2013) James D. Faix   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Gram-positive and gram-negative bacterial toxins in sepsis

(2013) Girish Ramachandran   Virulence

The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis

(2012) Eric P Schmidt et al.   NATURE MEDICINE

Normal-Range Blood Lactate Concentration in Septic Shock Is Prognostic and Predictive

(2012) Petch Wacharasint et al.   SHOCK

Evolution of peripheral vs metabolic perfusion parameters during septic shock resuscitation. A clinical-physiologic study

(2011) Glenn Hernandez et al.   JOURNAL OF CRITICAL CARE

Effect of Procalcitonin-Based Guidelines vs Standard Guidelines on Antibiotic Use in Lower Respiratory Tract Infections

(2009) Philipp Schuetz et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Circulating microRNAs as stable blood-based markers for cancer detection

(2008) P. S. Mitchell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA