Pharmacokinetics, Safety, and Tolerability of Single and Multiple Doses of Isavuconazonium Sulfate in Healthy Adult Japanese Subjects

Clinical experience with isavuconazole in healthy volunteers and patients with invasive aspergillosis in China, and the results from an exposure–response analysis

(2020) Jing Zhang et al.   MYCOSES

Clinical Pharmacokinetics and Pharmacodynamics of Isavuconazole

(2018) Matthew W. McCarthy et al.   CLINICAL PHARMACOKINETICS

Isavuconazole versus Caspofungin in the Treatment of Candidemia and Other Invasive Candida Infections: The ACTIVE Trial

(2018) Bart Jan Kullberg et al.   CLINICAL INFECTIOUS DISEASES

Variability and exposure–response relationships of isavuconazole plasma concentrations in the Phase 3 SECURE trial of patients with invasive mould diseases

(2018) Thomas Kaindl et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Isavuconazole Population Pharmacokinetic Analysis Using Nonparametric Estimation in Patients with Invasive Fungal Disease (Results from the VITAL Study)

(2016) Laura L. Kovanda et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Population Pharmacokinetics of Isavuconazole from Phase 1 and Phase 3 (SECURE) Trials in Adults and Target Attainment in Patients with Invasive Infections Due to Aspergillus and Other Filamentous Fungi

(2016) Amit Desai et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Isavuconazole absorption following oral administration in healthy subjects is comparable to intravenous dosing, and is not affected by food, or drugs that alter stomach pH

(2016) Anne Schmitt-Hoffmann et al.   INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS

Isavuconazole versus voriconazole for primary treatment of invasive mould disease caused by Aspergillus and other filamentous fungi (SECURE): a phase 3, randomised-controlled, non-inferiority trial

(2016) Johan A Maertens et al.   LANCET

Isavuconazole: A New Broad-Spectrum Triazole Antifungal Agent

(2015) Marisa H. Miceli et al.   CLINICAL INFECTIOUS DISEASES

Pharmacogenetics and human genetic polymorphisms

(2010) Ann K. Daly   BIOCHEMICAL JOURNAL

New and emerging treatments for fungal infections

(2007) A. C. Pasqualotto et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY