Paeoniflorin alleviates NG-nitro-L-arginine methyl ester (L-NAME)-induced gestational hypertension and upregulates silent information regulator 2 related enzyme 1 (SIRT1) to reduce H2O2-induced endothelial cell damage

Long noncoding RNA MALAT1 contributes to pregnancy‐induced hypertension development by enhancing oxidative stress and inflammation through the regulation of the miR‐150‐5p/ET‐1 axis

(2020) Minghui Ou et al.   FASEB JOURNAL

Melatonin attenuates hypertension and oxidative stress in a rat model of L-NAME-induced gestational hypertension

(2020) Junfang Zuo et al.   VASCULAR MEDICINE

Paeoniflorin Ameliorates Chronic Hypoxia/SU5416-Induced Pulmonary Arterial Hypertension by Inhibiting Endothelial-to-Mesenchymal Transition

(2020) Min Yu et al.   Drug Design Development and Therapy

Magnesium Lithospermate B Downregulates the Levels of Blood Pressure, Inflammation, and Oxidative Stress in Pregnant Rats with Hypertension

(2020) Kaixiang Xu et al.   International Journal of Hypertension

Searching for calcium antagonists for hypertension disease therapy from Moutan Cortex, using bioactivity integrated UHPLC-QTOF-MS

(2019) Yujie Lu et al.   PHYTOCHEMICAL ANALYSIS

Paeoniflorin improves pressure overload-induced cardiac remodeling by modulating the MAPK signaling pathway in spontaneously hypertensive rats

(2019) Xin Liu et al.   BIOMEDICINE & PHARMACOTHERAPY

Endothelial dysfunction as a long-term effect of late onset hypertensive pregnancy disorders: High BMI is key

(2018) L.J. Alma et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology

Combined Antihypertensive Effect of Paeoniflorin Enriched Extract and Metoprolol in Spontaneously Hypertensive Rats

(2018) Su-Hong Chen et al.   Pharmacognosy Magazine

Paeoniflorin attenuates oxidized low‐density lipoprotein‐induced apoptosis and adhesion molecule expression by autophagy enhancement in human umbilical vein endothelial cells

(2018) Yi Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Paeoniflorin Ameliorates Experimental Autoimmune Encephalomyelitis via Inhibition of Dendritic Cell Function and Th17 Cell Differentiation

(2017) Han Zhang et al.   Scientific Reports

Childhood Risk Factors and Pregnancy-Induced Hypertension: The Bogalusa Heart Study

(2016) Shengxu Li et al.   AMERICAN JOURNAL OF HYPERTENSION

Pregnancy-Induced hypertension

(2015) Evangelia Kintiraki et al.   Hormones-International Journal of Endocrinology and Metabolism

Paeoniflorin inhibition of 6-hydroxydopamine-induced apoptosis in PC12 cells via suppressing reactive oxygen species-mediated PKCδ/NF-κB pathway

(2015) H. Dong et al.   NEUROSCIENCE

PGC-1α regulation of mitochondrial degeneration in experimental diabetic neuropathy

(2014) Joungil Choi et al.   NEUROBIOLOGY OF DISEASE

Global causes of maternal death: a WHO systematic analysis

(2014) Lale Say et al.   Lancet Global Health

Paeoniflorin, the main active constituent of Paeonia lactiflora roots, attenuates bleomycin-induced pulmonary fibrosis in mice by suppressing the synthesis of type I collagen

(2013) Yu Ji et al.   JOURNAL OF ETHNOPHARMACOLOGY

Phosphatidylinositol 3 kinase/protein kinase B is responsible for the protection of paeoniflorin upon H2O2-induced neural progenitor cell injury

(2013) Y.-M. Wu et al.   NEUROSCIENCE

Paeoniflorin protects human EA.hy926 endothelial cells against gamma-radiation induced oxidative injury by activating the NF-E2-related factor 2/heme oxygenase-1 pathway

(2013) Jing Yu et al.   TOXICOLOGY LETTERS

Peoniflorin attentuates Aβ(1–42)-mediated neurotoxicity by regulating calcium homeostasis and ameliorating oxidative stress in hippocampus of rats

(2009) Shu-Zhi Zhong et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES