Article
Engineering, Biomedical
Camila Bussola Tovani, Thibaut Divoux, Sebastien Manneville, Thierry Azais, Guillaume Laurent, Marta de Frutos, Alexandre Gloter, Pietro Ciancaglini, Ana P. Ramos, Nadine Nassif
Summary: This study investigates the physiological and pathological effects of strontium (Sr2 +) on bone biomineralization. The results show that excessive levels of Sr2 + destabilize the mineral and collagen fibril assembly, leading to impaired cellular activity and correlating with bone-weakening disorders.
ACTA BIOMATERIALIA
(2023)
Article
Anthropology
Jeremy McCormack, Nicolas Bourgon, Virginie Sinet-Mathiot, Zeljko Rezek, Geoff M. Smith, Jean-Jacques Hublin, Mohammed Dabain, Helen Fewlass
Summary: This study tested the feasibility of analyzing the zinc isotope composition of dissolved mineral solutions during collagen extraction for carbon and nitrogen isotope analysis. The results show that with minor adjustments, the dissolved mineral solution from collagen extraction can be used for zinc isotope analysis, providing additional dietary information.
ARCHAEOLOGICAL AND ANTHROPOLOGICAL SCIENCES
(2022)
Article
Geography, Physical
Petra Vaiglova, Nicole A. Lazar, Elizabeth A. Stroud, Emma Loftus, Cheryl A. Makarewicz
Summary: Isotopic analysis is widely used in archaeology to gain insights from various organic and inorganic materials, but there are issues with the quality and reporting of findings. This paper addresses weaknesses in traditional applications of isotopic techniques, focusing on sample selection, data handling, and results reporting. It provides advice on building comparative baselines, statistical analysis, and effective communication. The guidance aims to improve the use of isotopic techniques in archaeology.
QUATERNARY INTERNATIONAL
(2023)
Article
Multidisciplinary Sciences
Michael Richards, Colin Smith, Olaf Nehlich, Vaughan Grimes, Darlene Weston, Alissa Mittnik, Johannes Krause, Keith Dobney, Yannis Tzedakis, Holley Martlew
Summary: In this study, biomolecular methods were used to investigate human mobility during the Neolithic and Bronze Age periods on Crete. The findings suggest that most individuals were local to Crete, with no evidence of large-scale movement from the Greek mainland or other areas. However, a few individuals from a Late Bronze Age cemetery showed isotope values inconsistent with Crete, indicating a possible origin elsewhere.
Article
Geochemistry & Geophysics
Xiao-Chun Li, Daniel E. Harlov, Mei-Fu Zhou, Hao Hu
Summary: A series of fluid/apatite reaction experiments were conducted to understand the effect of fluid-induced alteration on the Sm-Nd isotope system in apatite. The experimental results showed that fluid chemistry is the main factor controlling the response of the Sm-Nd isotopic system to fluid-induced alteration. When the fluids are rich in ligands that can facilitate REE mobilization and fractionation, the Sm-147/Nd-144 ratio of apatite can be highly modified, indicating the importance of evaluating the fluid-rock history and chemistry before using apatite Sm-Nd isotopes as geological indicators.
GEOCHIMICA ET COSMOCHIMICA ACTA
(2022)
Article
Anthropology
Veronika Zacherl, Gisela Grupe, Andrea Goehring
Summary: Stable isotope analysis is a routine method in archaeometry, and cluster analysis is superior to traditional evaluations in detecting multidimensional similarities among isotopic signatures. This study reevaluates previously published isotopic datasets from early medieval skeletal finds in Upper Bavaria, Germany, using Gaussian Mixture Model clustering to demonstrate its potential for paleodiet reconstruction.
ANTHROPOLOGISCHER ANZEIGER
(2023)
Article
Biochemistry & Molecular Biology
Leticia Rubio, Antonio Vargas, Patricia Rivera, Antonio J. Lopez-Gambero, Ruben Tovar, Julian K. Christians, Stella Martin-de-las-Heras, Fernando Rodriguez de Fonseca, Julie A. Chowen, Jesus Argente, Juan Suarez
Summary: Deficiency of PAPP-A2 gene affects bone composition and remodeling in mice, with acute IGF-1 treatment leading to short-term changes in bone composition and local IGF-1 response. The effects of rmIGF-1 treatment depend on sex, providing insights for potential IGF-1 therapy in growth failure and bone loss.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Chemistry, Multidisciplinary
Hassan Gharibi, Alexey L. Chernobrovkin, Gunilla Eriksson, Amir Ata Saei, Zena Timmons, Andrew C. Kitchener, Daniela C. Kalthoff, Kerstin Liden, Alexander A. Makarov, Roman A. Zubarev
Summary: The study unexpectedly found higher levels of deuterium in proline and hydroxyproline residues in bone collagen from seals, ruling out diet as a plausible mechanism for this anomalous enrichment and questioning the old adage "you are what you eat."
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Biochemical Research Methods
Noemi Procopio, Rachel J. A. Hopkins, Virginia L. Harvey, Michael Buckley
Summary: Isotope analyses are common in analyzing ancient bones for diet and chronology interpretation. Evaluating collagen yield is important for selecting adequate specimens, and this study used proteomic methods to investigate proteinaceous biomolecules in poorly preserved samples. While waste fractions contain significant proteins, their abundance does not correlate with collagen yield, suggesting they can still provide useful molecular information.
JOURNAL OF PROTEOME RESEARCH
(2021)
Article
Ecology
Richard P. Fiorella, Steven A. Kannenberg, William R. L. Anderegg, Russell K. Monson, James R. Ehleringer
Summary: Isotope ratios of tree-ring cellulose are important for reconstructing paleoclimate and plant response to environmental changes. This study found that the signal of carbohydrates exported from leaf to branch may deviate from mean leaf values if there is spatial heterogeneity in isotope ratios in the leaf. The result suggests that the conditions producing differential isotope effects between branch phloem and needle sugars could improve tree-ring-based climate reconstructions.
Article
Biochemical Research Methods
Timothy P. Cleland, Julianne J. Sarancha, Christine A. M. France
Summary: Proteomic techniques have provided a more comprehensive understanding of protein diagenesis in archaeology and paleontology, revealing various proteins in addition to collagen. The correlation between total deamidation and wt% N suggests a potential impact on nitrogen signal in bulk analyses. Despite varying sample quality, the amino acid profiles still reflect expected collagen I percentages, allowing for valid single amino acid stable isotope analyses.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY
(2021)
Article
Geography, Physical
Paola Iacumin, F. Balossi Restelli, Antonella Macri, Antonietta Di Matteo
Summary: The study integrates isotopic analyses of animal skeletal remains from the site of Arslantepe, indicating that goats and sheep provide the best information on variation of climatic conditions, while pigs and cattle give complementary information mainly related to breeding practices.
QUATERNARY INTERNATIONAL
(2021)
Article
Multidisciplinary Sciences
Clement P. Bataille, Klervia Jaouen, Stefania Milano, Manuel Trost, Sven Steinbrenner, Eric Crubezy, Rozenn Colleter
Summary: This study used sulfur isotope analysis of archaeological teeth collagen, combined with machine-learning regression and remote sensing data, to predict sulfur isotope variations in Western Europe, successfully pinpointing the geographic origins of animal and human teeth to specific regions in Brittany.
Article
Anthropology
Thibault Clauzel, Pascale Richardin, Jannick Ricard, Yves Le Bechennec, Romain Amiot, Francois Fourel, Diana Joseph, Arnauld Vincon-Laugier, Jean-Pierre Flandrois, Christophe Lecuyer
Summary: Stable hydrogen isotope measurement of body tissues presents challenges in analysis and interpretation, but comparing the hydrogen isotope composition of bone collagen, tooth enamel, and bulk bone can provide insights into climate and diet.
JOURNAL OF ARCHAEOLOGICAL SCIENCE
(2022)
Article
Anthropology
Eric J. Guiry, Paul Szpak
Summary: The carbon and nitrogen isotopic compositions of bone and tooth collagen are important for studying past biological, environmental, and cultural phenomena. Collagen provides reliable quality control criteria for isotopic data, with traditional C:N QC parameters sometimes leading to unreliable isotopic compositions due to contamination. New collagen QC criteria specific to certain taxa and environments have been proposed based on a model's results, aiming to improve the interpretation of isotopic data by accurately identifying contaminated samples.
JOURNAL OF ARCHAEOLOGICAL SCIENCE
(2021)
Article
Biochemical Research Methods
L. Gkoura, G. Diamantopoulos, M. Fardis, D. Homouz, S. Alhassan, M. Beazi-Katsioti, M. Karagianni, A. Anastasiou, G. Romanos, J. Hassan, G. Papavassiliou
Article
Biochemistry & Molecular Biology
Petros Karalis, Anastasia Elektra Poutouki, Theodora Nikou, Maria Halabalaki, Charalampos Proestos, Effie Tsakalidou, Sofia Gougoura, George Diamantopoulos, Maria Tassi, Elissavet Dotsika
Article
Biochemistry & Molecular Biology
George Diamantopoulos, Marios Katsiotis, Michael Fardis, Ioannis Karatasios, Saeed Alhassan, Marina Karagianni, George Papavassiliou, Jamal Hassan
Article
Multidisciplinary Sciences
E. Dotsika, P. Dalampakis, E. Spyridonos, G. Diamantopoulos, P. Karalis, M. Tassi, B. Raco, A. Arvanitis, N. Kolios, J. L. Michelot
Summary: The study of fluids from major geothermal fields in N/NE Greece shows distinct differences in hydrochemical and isotopic characteristics, indicating different source fluids and magmatic processes. The western geothermal systems are influenced by volatiles released from subducted marine sediments, while the eastern systems exhibit a mixture of crustal and mantle-derived volatiles.
SCIENTIFIC REPORTS
(2021)
Article
Chemistry, Analytical
Konstantina Papastavropoulou, Ioannis N. Pasias, Elissavet Dotsika, Emel Oz, Fatih Oz, Charalampos Proestos
Summary: The study evaluated the key quality characteristics of olive oil, focusing on biophenolic content and its impact on health and the contribution of various parameters to health claims. The findings showed that the biophenol contents in olive oil and its health claims were influenced by various parameters.
Article
Chemistry, Multidisciplinary
Amira Reda, Mustafa Eissa, Ibrahim El Shamy, Elissavet Dotsika, Mostafa Saied, Sayed Mosaad
Summary: This study investigates the scarce groundwater resources and geochemical processes affecting groundwater quality in the Qena Basin in the arid Eastern Desert of Egypt. It reveals that the groundwater in this basin mainly comes from recharge from the River Nile and paleo-water.
APPLIED SCIENCES-BASEL
(2022)
Proceedings Paper
Engineering, Civil
Petros Karalis, Maria Tassi, Eustathios Heliades, Georgios Diamantopoulos, Vassilios Christaras, Panagiotis Spathis, Elissavet Dotsika
Summary: This study presents isotopic signatures of quarries in different regions of Greece to enrich the existing databases used in ancient marble provenance research. It aims to enhance our understanding of ancient monuments and potentially identify economic and cultural associations, as well as trade routes. Moreover, it aims to reduce overlap in isotopic signals in current databases, facilitating the dissemination and provenance studies of ancient marble monuments.
PROTECTION OF HISTORICAL CONSTRUCTIONS, PROHITECH 2021
(2022)
Proceedings Paper
Engineering, Civil
Petros Karalis, Maria Tassi, Sofia Gougoura, George Diamantopoulos, Dafni Kyropoulou, Eustratios Heliades, Emmanouil Palaigeorgiou, Elissavet Dotsika
Summary: The study presents the important sources of salt weathering in stone monuments, including marine, atmospheric pollution, and building materials. It emphasizes the significant role of atmospheric sulfur and nitrogen in the formation of black crust. Isotopic measurements are used to distinguish different sources of sulfate salts.
PROTECTION OF HISTORICAL CONSTRUCTIONS, PROHITECH 2021
(2022)
Article
Anthropology
Elissavet Dotsika, Maria Tassi, Petros Karalis, Sofia Gougoura, Elena F. Kranioti, Dimitra E. Michael, Maria Kazou, Anastasia E. Poutouki, Georgios Diamantopoulos
Summary: Through isotopic analysis of ancient and modern Greek human bone collagen, it is found that the Greek diet has gradually become richer in high trophic level proteins, such as marine sources, with a larger variety of food sources over time.
AMERICAN JOURNAL OF BIOLOGICAL ANTHROPOLOGY
(2022)
Correction
Physics, Fluids & Plasmas
K. Lambropoulos, M. Chatzieleftheriou, A. Morphis, K. Kaklamanis, R. Lopp, M. Theodorakou, M. Tassi, C. Simserides