Nano‐enabled Tumor Systematic Energy Exhaustion via Zinc (II) Interference Mediated Glycolysis Inhibition and Specific GLUT1 Depletion

A Multichannel Ca 2+ Nanomodulator for Multilevel Mitochondrial Destruction‐Mediated Cancer Therapy

(2021) Pan Zheng et al.   ADVANCED MATERIALS

Redox-­activatable photothermal therapy and enzyme-mediated tumor starvation for synergistic cancer therapy

(2021) Xinlong He et al.   Nano Today

Nanoenabled Disruption of Multiple Barriers in Antigen Cross-Presentation of Dendritic Cells via Calcium Interference for Enhanced Chemo-Immunotherapy

(2020) Jingyi An et al.   ACS Nano

Porous Pt Nanospheres Incorporated with GOx to Enable Synergistic Oxygen‐Inductive Starvation/Electrodynamic Tumor Therapy

(2020) Zijie Lu et al.   Advanced Science

DNAzyme-Loading MOFs for Self-Sufficient Gene Therapy

(2019) Huimin Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nanoenabled Modulation of Acidic Tumor Microenvironment Reverses Anergy of Infiltrating T Cells and Potentiates Anti-PD-1 Therapy

(2019) Yu-Xue Zhang et al.   NANO LETTERS

Enhanced Tumor-Specific Disulfiram Chemotherapy by In Situ Cu2+ Chelation-Initiated Nontoxicity-to-Toxicity Transition

(2019) Wencheng Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Calcium-Overload-Mediated Tumor Therapy by Calcium Peroxide Nanoparticles

(2019) Meng Zhang et al.   Chem

Extravascular gelation shrinkage-derived internal stress enables tumor starvation therapy with suppressed metastasis and recurrence

(2019) Kun Zhang et al.   Nature Communications

A Versatile Prodrug Strategy to In Situ Encapsulate Drugs in MOF Nanocarriers: A Case of Cytarabine-IR820 Prodrug Encapsulated ZIF-8 toward Chemo-Photothermal Therapy

(2018) Huiyuan Zhang et al.   ADVANCED FUNCTIONAL MATERIALS

Metal-Organic Framework Nanoparticles

(2018) Shunzhi Wang et al.   ADVANCED MATERIALS

Metal-organic frameworks for precise inclusion of single-stranded DNA and transfection in immune cells

(2018) Shuang Peng et al.   Nature Communications

Zinc overload mediated by zinc oxide nanoparticles as innovative anti-tumor agent

(2018) Nadine Wiesmann et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Versatile Catalytic Deoxyribozyme Vehicles for Multimodal Imaging-Guided Efficient Gene Regulation and Photothermal Therapy

(2018) Jie Feng et al.   ACS Nano

Mannose impairs tumour growth and enhances chemotherapy

(2018) Pablo Sierra Gonzalez et al.   NATURE

Tumor Starvation Induced Spatiotemporal Control over Chemotherapy for Synergistic Therapy

(2018) Ming‐Kang Zhang et al.   Small

Zinc status is associated with inflammation, oxidative stress, lipid, and glucose metabolism

(2017) J. Olechnowicz et al.   Journal of Physiological Sciences

Magnesium silicide nanoparticles as a deoxygenation agent for cancer starvation therapy

(2017) Chen Zhang et al.   Nature Nanotechnology

A microRNA-initiated DNAzyme motor operating in living cells

(2017) Hanyong Peng et al.   Nature Communications

A Smart DNAzyme-MnO2Nanosystem for Efficient Gene Silencing

(2015) Huanhuan Fan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Targeting glucose uptake with siRNA-based nanomedicine for cancer therapy

(2015) Cong-Fei Xu et al.   BIOMATERIALS

Zeolitic Imidazole Framework (ZIF) Nanospheres for Easy Encapsulation and Controlled Release of an Anticancer Drug Doxorubicin under Different External Stimuli: A Way toward Smart Drug Delivery System

(2015) Chandan Adhikari et al.   MOLECULAR PHARMACEUTICS

Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH

(2015) J. Yun et al.   SCIENCE

Molecular drivers of cellular metabolic reprogramming in melanoma

(2015) Cecilie Abildgaard et al.   TRENDS IN MOLECULAR MEDICINE

Tumor glycolysis as a target for cancer therapy: progress and prospects

(2013) Shanmugasundaram Ganapathy-Kanniappan et al.   Molecular Cancer

Cytotoxic/tumor suppressor role of zinc for the treatment of cancer: an enigma and an opportunity

(2011) Leslie C Costello et al.   Expert Review of Anticancer Therapy

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

(2010) Kai Kessenbrock et al.   CELL

Intracellular Zn2+ Accumulation Contributes to Synaptic Failure, Mitochondrial Depolarization, and Cell Death in an Acute Slice Oxygen-Glucose Deprivation Model of Ischemia

(2009) Y. V. Medvedeva et al.   JOURNAL OF NEUROSCIENCE