4.8 Review

Protein Nanoparticles: Uniting the Power of Proteins with Engineering Design Approaches

Journal

ADVANCED SCIENCE
Volume 9, Issue 8, Pages -

Publisher

WILEY
DOI: 10.1002/advs.202104012

Keywords

biomimetic; electrospraying; nanomedicine; protein nanoparticle; self-assembly

Funding

  1. Defense Threat Reduction Agency (DTRA) [HDTRA1-15-0045]
  2. National Science Foundation Graduate Research Fellowship [DGE 1256260]

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This review summarizes recent trends in the preparation, application, and chemical construction of protein nanoparticles, with a particular focus on their potential breakthroughs in nanomedicine.
Protein nanoparticles, PNPs, have played a long-standing role in food and industrial applications. More recently, their potential in nanomedicine has been more widely pursued. This review summarizes recent trends related to the preparation, application, and chemical construction of nanoparticles that use proteins as major building blocks. A particular focus has been given to emerging trends related to applications in nanomedicine, an area of research where PNPs are poised for major breakthroughs as drug delivery carriers, particle-based therapeutics or for non-viral gene therapy.

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