4.6 Article

Biomanufacturing in low Earth orbit for regenerative medicine

Journal

STEM CELL REPORTS
Volume 17, Issue 1, Pages 1-13

Publisher

CELL PRESS
DOI: 10.1016/j.stemcr.2021.12.001

Keywords

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Funding

  1. NSF/CMMI [2028635]
  2. American Heart Association Career Development Award [856987]
  3. Translational Research Institute through NASA [20-20TSRAD-2-0007]
  4. [NIHUH3TR003519]
  5. Directorate For Engineering
  6. Div Of Civil, Mechanical, & Manufact Inn [2028635] Funding Source: National Science Foundation

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The 2020 Biomanufacturing in Space Symposium reviewed research in regenerative medicine in space and discussed opportunities to advance biomanufacturing for regenerative medicine in low Earth orbit. The symposium identified areas where financial investments could stimulate advancements overcoming technical barriers and highlighted opportunities in disease modeling, stem-cell-derived products, and biofabrication. The symposium will initiate a roadmap to establish a sustainable market for regenerative medicine biomanufacturing in space.
Research in low Earth orbit (LEO) has become more accessible. The 2020 Biomanufacturing in Space Symposium reviewed space-based regenerative medicine research and discussed leveraging LEO to advance biomanufacturing for regenerative medicine applications. The symposium identified areas where financial investments could stimulate advancements overcoming technical barriers. Opportunities in disease modeling, stem-cell-derived products, and biofabrication were highlighted. The symposium will initiate a roadmap to a sustainable market for regenerative medicine biomanufacturing in space. This perspective summarizes the 2020 Biomanufacturing in Space Symposium, highlights key biomanufacturing opportunities in LEO, and lays the framework for a roadmap to regenerative medicine biomanufacturing in space.

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