METTL3-mediated m6A mRNA modification promotes esophageal cancer initiation and progression via Notch signaling pathway

Emerging Role of Non-Coding RNAs in Esophageal Squamous Cell Carcinoma

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m6A Modification in Coding and Non-coding RNAs: Roles and Therapeutic Implications in Cancer

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METTL3 Promotes Tumorigenesis and Metastasis through BMI1 m6A Methylation in Oral Squamous Cell Carcinoma

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Role of METTL3-Dependent N6-Methyladenosine mRNA Modification in the Promotion of Angiogenesis

(2020) Mu-Di Yao et al.   MOLECULAR THERAPY

Upregulation of METTL3 Expression Predicts Poor Prognosis in Patients with Esophageal Squamous Cell Carcinoma

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Reduced Expression of METTL3 Promotes Metastasis of Triple-Negative Breast Cancer by m6A Methylation-Mediated COL3A1 Up-Regulation

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Adenylate Kinase 4 Modulates the Resistance of Breast Cancer Cells to Tamoxifen through an m6A-Based Epitranscriptomic Mechanism

(2020) Xiaochuan Liu et al.   MOLECULAR THERAPY

Targeting Notch in oncology: the path forward

(2020) Samarpan Majumder et al.   NATURE REVIEWS DRUG DISCOVERY

Dynamic m6A mRNA methylation reveals the role of METTL3-m6A-CDCP1 signaling axis in chemical carcinogenesis

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Regulation of Gene Expression by N-methyladenosine in Cancer

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N6-methyladenosine modification of ITGA6 mRNA promotes the development and progression of bladder cancer

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m6A mRNA methylation initiated by METTL3 directly promotes YAP translation and increases YAP activity by regulating the MALAT1-miR-1914-3p-YAP axis to induce NSCLC drug resistance and metastasis

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Molecular landscape of esophageal cancer: implications for early detection and personalized therapy

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Cancer statistics, 2018

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The notch pathway is activated in neoplastic progression in esophageal squamous cell carcinoma

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Mettl1/Wdr4-Mediated m 7 G tRNA Methylome Is Required for Normal mRNA Translation and Embryonic Stem Cell Self-Renewal and Differentiation

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Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

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mRNA circularization by METTL3–eIF3h enhances translation and promotes oncogenesis

(2018) Junho Choe et al.   NATURE

CCGD-ESCC: A Comprehensive Database for Genetic Variants Associated with Esophageal Squamous Cell Carcinoma in Chinese Population

(2018) Linna Peng et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Interplay between Notch1 and Notch3 promotes EMT and tumor initiation in squamous cell carcinoma

(2017) Mitsuteru Natsuizaka et al.   Nature Communications

The m 6 A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells

(2016) Shuibin Lin et al.   MOLECULAR CELL

Post-transcriptional gene regulation by mRNA modifications

(2016) Boxuan Simen Zhao et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Genetic landscape of esophageal squamous cell carcinoma

(2014) Yi-Bo Gao et al.   NATURE GENETICS

A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

(2013) Jianzhao Liu et al.   Nature Chemical Biology

ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility

(2012) Guanqun Zheng et al.   MOLECULAR CELL

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

(2011) Guifang Jia et al.   Nature Chemical Biology