Article
Cardiac & Cardiovascular Systems
Xuerong Sun, Bin Zhou, Keping Chen, Wei Hua, Yangang Su, Wei Xu, Fang Wang, Xiaohan Fan, Hongxia Niu, Yan Dai, Zhimin Liu, Shuang Zhao, Shu Zhang
Summary: The study found apparent non-linear associations between night-time heart rate and ventricular tachyarrhythmias (VTAs) and ICD shocks. An increasing incidence of VTAs and ICD shocks was observed at both low and high levels of night-time heart rate, with a night-time heart rate of 50-70 bpm potentially being the optimal therapeutic target for the management of ICD/CRT-D recipients.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Shengwen Yang, Junhan Zhao, Xi Liu, Jing Wang, Min Gu, Chi Cai, Hongxia Niu, Liang Chen, Wei Hua
Summary: Metabolomics analysis identified dysregulated metabolites associated with life-threatening ventricular arrhythmias and potential biomarkers. Implantable cardioverter defibrillators reduce sudden cardiac death, but current strategies for patient selection and risk stratification are inefficient.
JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH
(2023)
Article
Cardiac & Cardiovascular Systems
Ewa Jedrzejczyk-Patej, Michal Mazurek, Monika Lazar, Patrycja Pruszkowska-Skrzep, Adam Sokal, Jacek Kowalczyk, Oskar Kowalski, Zbigniew Kalarus, Radoslaw Lenarczyk
Summary: The benefit of implantable cardioverter-defibrillators (ICD) in non-ischemic systolic heart failure (NICM) patients is uncertain. This study aimed to investigate the incidence, predictors, and prognostic impact of ventricular arrhythmias in NICM patients with ICD. The results showed that ventricular arrhythmias occurred in approximately one-fourth of NICM and ICD patients, and were associated with worse prognosis compared to those without sustained ventricular arrhythmias.
KARDIOLOGIA POLSKA
(2023)
Article
Cardiac & Cardiovascular Systems
Victor Waldmann, Christelle Marquie, Francis Bessiere, David Perrot, Frederic Anselme, Nicolas Badenco, Sergio Barra, Geraldine Bertaux, Hugues Blangy, Pierre Bordachar, Serge Boveda, Michel Chauvin, Nicolas Clementy, Gael Clerici, Nicolas Combes, Pascal Defaye, Jean-Claude Deharo, Philippe Durand, Guillaume Duthoit, Romain Eschalier, Laurent Fauchier, Rodrigue Garcia, Olivier Geoffroy, Edouard Gitenay, Jean-Baptiste Gourraud, Charles Guenancia, Laurence Iserin, Peggy Jacon, Laurence Jesel-Morel, Fawzi Kerkouri, Didier Klug, Linda Koutbi, Fabien Labombarda, Magalie Ladouceur, Gabriel Laurent, Christophe Leclercq, Baptiste Maille, Alice Maltret, Gregoire Massoulie, Pierre Mondoly, Sandro Ninni, Pierre Ollitrault, Jean-Luc Pasquie, Bertrand Pierre, Penelope Pujadas, Laure Champ-Rigot, Frederic Sacher, Nicolas Sadoul, Alexandre Schatz, Pierre Winum, Paul-Ursmar Milliez, Vincent Probst, Eloi Marijon
Summary: This study analyzed the outcomes of subcutaneous implantable cardioverter-defibrillators (S-ICDs) in patients with congenital heart disease (CHD). Among 4,924 patients who received an S-ICD implant, 101 had CHD. The study found that S-ICDs are effective and safe in patients with CHD.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Pierre Antoine Le Bos, Margaux Pontailler, Alice Maltret, Diala Kraiche, Regis Gaudin, Claudio Barbanti, Eloi Marijon, Olivier Raisky, Damien Bonnet, Victor Waldmann
Summary: This study aimed to compare outcomes of epicardial versus transvenous implantable cardioverter defibrillators (ICDs) in children. The results showed that epicardial ICDs had more early and late complications compared to transvenous ICDs, but the association between ICD lead dysfunction and reintervention was no longer significant after controlling for confounding factors such as age and weight. Additionally, pleural coils were associated with better outcomes than epicardial coils in this population.
Article
Cardiac & Cardiovascular Systems
Arwa Younis, Ilan Goldenberg, Shamroz Farooq, Hagai Yavin, James Daubert, Merritt Raitt, Alexander Mazur, David T. Huang, Brent L. Mitchell, Mayer R. Rashtian, Stephen Winters, Margot Vloka, Mehmet Aktas, Matthew A. Bernabei, Christopher A. Beck, Scott McNitt, Wojciech Zareba
Summary: The study analyzed data from the RAID trial and found that ranolazine treatment reduced VTA burden in patients at high risk, particularly in those without concomitant AAD therapy, cardiac resynchronization therapy (CRT)-treated patients, and patients without atrial fibrillation (AF). However, the addition of ranolazine did not affect VTA burden in patients already on AADs or those with AF.
JACC-CLINICAL ELECTROPHYSIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Mi Kyoung Song, Jae-Sun Uhm, Jae Suk Baek, Ja Kyoung Yoon, Jae Yoon Na, Hee Tae Yu, Ji-Hyuk Yang, Seil Oh, Sang Weon Park, Jinyoung Song, June Huh, Eun-Jung Bae
Summary: A Korean multicenter study found that the utilization rate of ICD therapy in pediatric patients was relatively low, but there was a high rate of appropriate shock occurrence. Efforts are needed to increase the use of ICDs to save the lives of high-risk patients and reduce the incidence of inappropriate shocks.
CIRCULATION JOURNAL
(2021)
Review
Cardiac & Cardiovascular Systems
Jayson R. Baman, Kaustubha D. Patil, Ankit N. Medhekar, Jane E. Wilcox
Summary: HFrecEF is recognized as a distinct clinical entity with increasing prevalence, and continued guideline-directed medical therapy is crucial to promote myocardial recovery. Despite the lower risk of sudden cardiac death in HFrecEF compared to HFrEF, the benefits of continued ICD therapy need to be weighed against potential risks and limitations.
JOURNAL OF CARDIAC FAILURE
(2021)
Article
Cardiac & Cardiovascular Systems
Jonas Pausch, Julian Mersmann, Oliver D. Bhadra, Markus J. Barten, Tobias Toennis, Yalin Yildirim, Simon Pecha, Hermann Reichenspurner, Alexander M. Bernhardt
Summary: The prognostic impact of ICD therapy in LVAD recipients remains controversial. ICD therapy in LVAD recipients was not associated with a survival benefit or reduced morbidity after LVAD implantation.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Review
Cardiac & Cardiovascular Systems
Johanna B. Tonko, Christopher A. Rinaldi
Summary: Implantable cardioverter-defibrillators (ICDs) have revolutionized the treatment of cardiac diseases. However, there is a need for alternative ICD configurations due to expanding patient groups and increasing complications associated with traditional devices.
Article
Medicine, General & Internal
Alwin B. P. Noordman, Michiel Rienstra, Yuri Blaauw, Bart A. Mulder, Alexander H. Maass
Summary: This study investigates the occurrence of appropriate ICD therapies and inappropriate shocks in secondary prevention ICD recipients with ventricular arrhythmia of unclear cause and underlying heart disease. It found that ventricular arrhythmia of unclear cause was significantly associated with fewer appropriate ICD therapies.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Alex Horby Christensen, Pyotr G. Platonov, Anneli Svensson, Henrik K. Jensen, Christine Rootwelt-Norberg, Pia Dahlberg, Trine Madsen, Tanja Charlotte Frederiksen, Tiina Helio, Kristina H. Haugaa, Henning Bundgaard, Jesper H. Svendsen
Summary: This study describes the complications associated with implantable cardioverter-defibrillators (ICD) treatment in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC). The results show that during long-term follow-up, approximately 41% of patients experienced potentially life-saving ICD therapy, while 27% had complications requiring surgery, mainly lead-related complications.
Article
Cardiac & Cardiovascular Systems
Ibrahim El-Battrawy, Katharina Koepsel, David Tenbrink, Boldizsar Kovacs, Tobias C. Dreher, Christian Blockhaus, Michael Gotzmann, Norbert Klein, Thomas Kuntz, Dong-In Shin, Hendrik Lapp, Stephanie Rosenkaimer, Mohammad Abumayyaleh, Nazha Hamdani, Ardan Muammer Saguner, Jacqueline Kowitz, Julia W. Erath, Firat Duru, Andreas Muegge, Ibrahim Akin, Assem Aweimer, Thomas Beiert
Summary: This study shows that the use of wearable cardioverter-defibrillator (WCD) may be beneficial for the treatment of patients with myocarditis. Prior ventricular arrhythmia may be a better predictor of risk than a reduced left ventricular ejection fraction <35% in this population.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Review
Cardiac & Cardiovascular Systems
Blandine Mondesert, Jeremy P. Moore, Paul Khairy
Summary: Due to advancements in surgical techniques and cardiology care, Fontan patients are living longer and require multidisciplinary expertise to manage complications in adulthood. Arrhythmias are common in Fontan patients and are influenced by anatomy, surgical technique, and postoperative care. Diagnostic tools, treatments, and device strategies for arrhythmias in Fontan patients should consider their specific anatomy, surgical repair, and clinical status. Cardiac implantable electronic devices (CIEDs) have greatly improved the management of Fontan patients, but the unique challenges of this patient population require careful consideration.
CANADIAN JOURNAL OF CARDIOLOGY
(2022)
Review
Cardiac & Cardiovascular Systems
Michal Miroslaw Farkowski, Michal Karlinski, Mariusz Pytkowski, Carlo de Asmundis, Michal Lewandowski, Giacomo Mugnai, Giulio Conte, Eloi Marijon, Ante Anic, Serge Boveda, Rui Providencia
Summary: This study systematically reviewed the effectiveness and safety of oral mexiletine in adult patients with structural heart disease and implantable cardioverter defibrillators for recurrent ventricular arrhythmia. The results showed that mexiletine reduced the number of ICD therapies, especially in patients where catheter ablation was not successful or contraindicated. However, in patients with ischemic cardiomyopathy, mexiletine seemed to be less effective than catheter ablation. The main side effects of mexiletine were related to gastrointestinal and neurological systems.
Article
Cardiac & Cardiovascular Systems
Luuk H. G. A. Hopman, Julia E. Visch, Pranav Bhagirath, Anja M. van der Laan, Mark J. Mulder, Orod Razeghi, Michiel J. B. Kemme, Steven A. Niederer, Cornelis P. Allaart, Marco J. W. Gotte
Summary: This study found that right atrial remodeling parameters were not predictive of atrial fibrillation (AF) recurrence after AF ablation. Bi-atrial fibrotic remodeling is present in patients with AF, and the amount of left atrial (LA) fibrosis has a strong correlation with the amount of right atrial (RA) fibrosis.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2023)
Article
Computer Science, Interdisciplinary Applications
Annejet Heida, Willemijn F. B. van der Does, Mathijs S. van Schie, Lianne N. van Staveren, Yannick J. H. J. Taverne, Ad J. J. C. Bogers, Natasja M. S. de Groot
Summary: This study compared conduction heterogeneity between the supervulnerable period after electrical cardioversion and long-term sinus rhythm in patients with atrial fibrillation (AF). The findings suggest that there might be no difference in biatrial conduction characteristics between these two periods.
MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING
(2023)
Article
Engineering, Biomedical
Cornelis W. van der Heiden, Casper F. Zijderhand, Kevin M. Veen, Alina A. Constantinescu, Olivier C. Manintveld, Jasper J. Brugts, Jos A. Bekkers, Ozcan Birim, Ad J. J. C. Bogers, Kadir Caliskan
Summary: We investigated the incidence of mechanical device malfunction in LVADs and found that it occurred significantly less in HeartMate 3 patients compared to HeartMate II patients.
Article
Public, Environmental & Occupational Health
M. J. Sarink, W. A. van Cappellen, A. G. M. Tielens, A. van Dijk, A. J. J. C. Bogers, J. E. M. de Steenwinkel, M. C. Vos, J. A. Severin, J. J. van Hellemond
Summary: The presence of V. vermiformis in water-based heater-cooler units can contribute to the persistent presence of M. chimaera. Cleaning and disinfection protocols should take this phenomenon into account.
JOURNAL OF HOSPITAL INFECTION
(2023)
Article
Cardiac & Cardiovascular Systems
Maurits S. H. Blomjous, Ties A. Mulders, Ali R. Wahadat, Wilco Tanis, Ad J. J. C. Bogers, Jolien W. Roos-Hesselink, Ricardo P. J. Budde
Summary: This study evaluated the normal imaging findings in non-infected patients after sternotomy using F-18-FDG-PET/CT, and found that sternal F-18-FDG uptake decreased significantly from 5 weeks to 55 weeks post-surgery, although elevated uptake patterns may persist.
JOURNAL OF NUCLEAR CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Luuk H. G. A. Hopman, Irene M. Frenaij, Raschel D. van Luijk, Marielle C. van de Veerdonk, Marco J. W. Goette, Cornelis P. Allaart
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2023)
Article
Cardiac & Cardiovascular Systems
Jorik H. Amesz, Sanne J. J. Langmuur, Nina Epskamp, Ad J. J. C. Bogers, Natasja M. S. de Groot, Olivier C. Manintveld, Yannick J. H. J. Taverne
Summary: This study evaluated the direct biomechanical effects of SGLT2 inhibitor empagliflozin on myocardium from end-stage heart failure patients. The results demonstrate that empagliflozin improves contraction and relaxation kinetics without diminishing maximum force production.
CARDIOVASCULAR DRUGS AND THERAPY
(2023)
Article
Cardiac & Cardiovascular Systems
C. Pelosi, R. M. Kauling, J. A. A. E. Cuypers, E. M. W. J. Utens, A. E. van den Bosch, I. Kardys, A. J. J. C. Bogers, W. A. Helbing, J. W. Roos-Hesselink, Jeroen S. Legerstee
Summary: Nowadays, the long-term impact on executive functioning in adults with congenital heart disease (CHD) operated in childhood is not completely understood.
CLINICAL RESEARCH IN CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Luuk H. G. A. Hopman, Mark J. Mulder, Anja M. van der Laan, Pranav Bhagirath, Ahmet Demirkiran, Martin B. von Bartheld, Michiel J. B. Kemme, Albert C. van Rossum, Cornelis P. Allaart, Marco J. W. Gotte
Summary: This study assesses the relationship between different left atrial (LA) strain methods and atrial fibrillation (AF) recurrence, comparing LA feature tracking (FT) strain with novel rapid LA strain approaches. The results show that both LA rapid strain and LA FT strain are associated with arrhythmia recurrence after ablation in AF patients. Therefore, LA rapid strain can be a convenient and reproducible alternative for assessing LA function in clinical practice.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Article
Multidisciplinary Sciences
Jorik H. Amesz, Natasja M. S. de Groot, Sanne J. J. Langmuur, Hamid el Azzouzi, Vera P. C. Tiggeloven, Manuela M. M. M. van Rooij, P. Knops, Ad J. J. C. Bogers, Yannick J. H. J. Taverne
Summary: We introduced a novel method to produce living myocardial slices (LMS) from human atria, which can maintain the 3D microarchitecture and multicellularity of intact human myocardium. These LMS can overcome the limitations of conventional myocardial cell cultures and bridge the gap between in-vitro and in-vivo atrial arrhythmia studies. This state-of-the-art platform can be used to investigate arrhythmia mechanisms and test novel therapies.
SCIENTIFIC REPORTS
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Wouter Bakhuis, Lea Betser, Amir H. Sadeghi, Dominique Gossot, Denis Susa, Alexander P. W. M. Maat, Sabrina Siregar, Ad J. J. C. Bogers, Agathe Seguin-Givelet, Edris A. F. Mahtab
Article
Cardiac & Cardiovascular Systems
Maximiliaan L. Notenboom, Art Schuermans, Jonathan R. G. Etnel, Kevin M. Veen, Pieter C. van de Woestijne, Filip R. Rega, Willem A. Helbing, Ad J. J. C. Bogers, Johanna J. M. Takkenberg
Summary: This study aims to provide decision-making support for children undergoing aortic valve replacement (AVR) by reviewing published outcomes and estimating age-specific outcomes with different valve substitutes. The results show suboptimal outcomes in pediatric AVR, especially in young patients, with high mortality and reintervention risks.
EUROPEAN HEART JOURNAL
(2023)
Review
Cardiac & Cardiovascular Systems
Sofie Rohde, Theo M. M. H. de By, Ad J. J. C. Bogers, Martin Schweiger
Summary: This systematic review aims to summarize the clinical course in paediatric patients after weaning from a ventricular assist device (VAD). The study found that the incidence rate of myocardial recovery during VAD support was 8.7%, and long-term recovery is achievable. More research is needed to understand this favorable outcome after VAD support.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Jette J. Peek, Wouter Bakhuis, Amir H. Sadeghi, Kevin M. Veen, Arno A. W. Roest, Nico Bruining, Theo van Walsum, Mark G. Hazekamp, Ad J. J. C. Bogers
Summary: This study examines the added value of 3D printing and 3D virtual reality models for surgical planning in complex double outlet right ventricle (DORV) patients. The results show that both methods provide better visualization of spatial relationships compared to 2D imaging, leading to more accurate surgical planning.
INTERDISCIPLINARY CARDIOVASCULAR AND THORACIC SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Rohit K. Kharbanda, Nawin L. Ramdat Misier, Mathijs S. van Schie, Roxanne D. Zwijnenburg, Jorik H. Amesz, Paul Knops, Ad J. J. C. Bogers, Yannick J. H. J. Taverne, Natasja M. S. de Groot
Summary: Low-level vagus nerve stimulation through the tragus (tLLVNS) is a therapeutic strategy for atrial fibrillation. This study showed that tLLVNS led to significant increase in unipolar potential voltage and observed changes in other electrophysiological properties in some patients.
JACC-CLINICAL ELECTROPHYSIOLOGY
(2023)