Article
Materials Science, Coatings & Films
Jing Hong, Yongfeng Qian, Lin Zhang, Hu Huang, Minqiang Jiang, Jiwang Yan
Summary: Orthogonal experiments were conducted to study the effects of laser nitriding on the surface hardness of Zr-based metallic glass, demonstrating a significant improvement in surface hardness could be achieved by selecting appropriate laser irradiation parameters.
SURFACE & COATINGS TECHNOLOGY
(2021)
Article
Nanoscience & Nanotechnology
Di Zhang, Yongfeng Qian, Lin Zhang, Hu Huang, Jiwang Yan
Summary: In this study, laser surface alloying technology was used to modify Zr-based metallic glass, increasing its hardness and wear resistance. The laser alloyed layer, composed mainly of in situ formed ZrSi2 phase and residual Si, exhibited significantly higher hardness compared to the as-cast surface.
SCRIPTA MATERIALIA
(2022)
Article
Chemistry, Physical
Yang Jiao, Emmanuel Brousseau, Wayne Nishio Ayre, Edward Gait-Carr, Xiaojun Shen, Xiaoxiang Wang, Samuel Bigot, Hanxing Zhu, Weifeng He
Summary: This study demonstrated the feasibility of using nanosecond laser surface texturing to modify the cytocompatibility of a Zr-based BMG material, with grooved surfaces showing higher cell viability and better adhesion. The improved cytocompatibility of the groove-textured sample was attributed to higher surface roughness, increased presence of metallic oxides, and enhanced hydrophilicity.
APPLIED SURFACE SCIENCE
(2021)
Article
Nanoscience & Nanotechnology
Yang Jiao, Emmanuel Brousseau, Koji Kosai, Alexander. J. G. Lunt, Jiwang Yan, Quanquan Han, Hanxing Zhu, Samuel Bigot, Weifeng He
Summary: The study demonstrates that laser surface melting can modify the hardness and shear banding behavior of bulk metallic glasses. Surface hardening and softening effects were observed post-LSM, with the introduction of compressive residual stress leading to increased surface hardening, and tensile residual stress resulting in surface softening. Differences in shear-banding mechanisms were detected near the surface, with reduced serrated flow and increased surface shear bands observed with compressive residual stress, and more pronounced serrated flows and deeper shear banding activity promoted with tensile residual stress following LSM.
MATERIALS SCIENCE AND ENGINEERING A-STRUCTURAL MATERIALS PROPERTIES MICROSTRUCTURE AND PROCESSING
(2021)
Article
Materials Science, Coatings & Films
Yongfeng Qian, Di Zhang, Jing Hong, Lin Zhang, Minqiang Jiang, Hu Huang, Jiwang Yan
Summary: Metallic glasses (MGs) are advanced structural materials with superior mechanical properties. This study investigates the use of SiC particles as reinforcement to improve the mechanical properties of Zr-based MG through laser surface alloying. The experimental results show that the laser-alloyed surface layers exhibit significantly improved hardness compared with the as-cast specimen, with an average hardness of 28.91 GPa at a relatively high overlap ratio of 70%.
SURFACE & COATINGS TECHNOLOGY
(2022)
Review
Automation & Control Systems
Zongjie Chen, Jin Yang, Hongbing Liu, Yixuan Zhao, Rui Pan
Summary: This paper provides an overview of the advances in the fabrication of functionalized metallic surfaces using ultrafast laser micromachining. It discusses the principles of interaction between ultrafast laser and metallic materials, presents state-of-the-art knowledge on fabrication methods based on surface topography, and highlights the functionalized properties of laser micro-machined metals. Furthermore, it addresses the challenges and future prospects of surface functionalized metals.
INTERNATIONAL JOURNAL OF ADVANCED MANUFACTURING TECHNOLOGY
(2022)
Article
Automation & Control Systems
Hu Huang, Jing Hong, Yongfeng Qian, Chao Wang, Zhiyu Zhang, Lin Zhang
Summary: Nanosecond pulsed laser nitriding is a promising technique for improving the surface hardness of Zr-based metallic glass. However, it often results in irregular surface profile and poor surface roughness. This study introduces nanosecond laser polishing as a post-machining approach to flatten the laser nitrided surface and effectively reduce surface roughness.
INTERNATIONAL JOURNAL OF ADVANCED MANUFACTURING TECHNOLOGY
(2022)
Article
Optics
Hanxuan Huang, Peilei Zhang, Zhishui Yu, Lei Shen, Haichuan Shi, Yingtao Tian
Summary: This study investigated the formation of micro-nano textures on the surface of Zr55Cu16Ni15Ti10Al4 bulk amorphous alloy induced by femtosecond laser, comparing different structural characteristics and analyzing the effects of various process parameters. It was found that the self-organized microholes structure had the best effect in reducing bacterial adhesion on the material surface.
OPTICS AND LASER TECHNOLOGY
(2022)
Article
Chemistry, Physical
Qinghua Wang, Huixin Wang, Zhixian Zhu, Nan Xiang, Zhandong Wang, Guifang Sun
Summary: The study presents a laser-based surface texturing method for switchable wettability control on titanium surface, enabling efficient transition between superhydrophilicity and superhydrophobicity. The reversible wettability transition is attributed to the dual-scale surface structure and controllable surface chemistry. The method allows practical throughput for large-area processing and various industrial applications.
SURFACES AND INTERFACES
(2021)
Article
Materials Science, Multidisciplinary
Hongyang Zhang, Yongfeng Qian, Lin Zhang, Di Zhang, Hanlin Liu, Hu Huang
Summary: By using nanosecond pulsed laser irradiation in ambient atmosphere, this study successfully achieved four different surface colors for metallic glasses. The surfaces of the colored metallic glasses were found to have formed oxides, leading to the color effect being attributed to the interference of oxide films.
Article
Engineering, Manufacturing
S. Mekhiel, Philip Koshy, M. A. Elbestawi
Summary: This research explores the potential of additive texturing (AT) to enhance the functionality of AM products by tailoring the topography of AM parts in process to include textures.
ADDITIVE MANUFACTURING
(2021)
Article
Materials Science, Ceramics
Wenzhe Zhang, Jiankang Huang, Yanqin Huang, Xiaoquan Yu, Ding Fan
Summary: The crystallization behavior of the amorphous alloy/crystalline metal welding interface is studied by pulsed laser butt welding method on Zr-based amorphous alloy and copper crystals. The results show the appearance of Zr2Cu and Zr2Ni crystal phases at the interface and the formation of a Cu rich region on the amorphous side. The diffusion of Zr, Ni, Ti to the Cu side leads to the formation of ZrO2, TiO2, CuO oxides on the sample's surface, causing changes in the voltage potential at the interface.
JOURNAL OF NON-CRYSTALLINE SOLIDS
(2023)
Article
Chemistry, Physical
Jing Hong, Haoxiang Wu, Hu Huang, Lin Zhang, Zhiyu Zhang, Minqiang Jiang, Jiwang Yan
Summary: In this study, nanosecond laser nitriding was used to improve the surface hardness and tribological characteristics of metallic glasses. Three laser nitrided surfaces with different hardness were prepared and their tribological characteristics were systematically investigated. The results showed that the hardness of the laser nitrided surfaces increased by 47.94%, 114.56%, and 171.99% compared to the original alloy, and the coefficients of friction were reduced by 29.12%, 65.05%, and 71.84%, respectively. Additionally, the scratch damage mechanisms were analyzed based on the various features of residual scratches and surrounding chips under different conditions.
Article
Engineering, Manufacturing
S. H. Chen, Q. Ge, J. S. Zhang, W. J. Chang, J. C. Zhang, H. H. Tang, H. D. Yang
Summary: Zr57 BMG showed excellent machinability at low-speed cutting with superior surface roughness and no crystallization. Scale-like patterns were observed on the machined surface due to plastic flow, which could be effectively suppressed by adjusting cutting parameters.
JOURNAL OF MANUFACTURING PROCESSES
(2021)
Article
Automation & Control Systems
Sefika Kasman, Ibrahim Can Ucar, Sertan Ozan
Summary: The surface of the commercial CoCr28Mo alloy was textured using a 20W pulsed fiber laser with different beam scan strategies, resulting in a chaotic texture formation. The surface roughness ranged from 1 to 7 μm, while the surface topography significantly affected the wettability. The optimal parameters for the laser engraving process were determined using the Taguchi method.
INTERNATIONAL JOURNAL OF ADVANCED MANUFACTURING TECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Liuwei Qin, Hui Xie, Nan Xiang, Min Wang, Shouan Han, Mingqi Pan, Xinbo Guo, Wen Zhang
Summary: This study investigated the influences of different climatic conditions on grape coloring and quality formation. Two common varieties of grapes were grown in Urumqi and Turpan, China, and the results showed that grapes grown in Urumqi had lower brightness value and higher red-green value compared to those grown in Turpan. The higher transcription of key genes related to anthocyanin biosynthesis in Urumqi grapes resulted in more abundant phenolic substances, especially anthocyanins. The maximum antioxidant activity was also observed in Urumqi grapes. These findings provide insights into the impact of climate on grape quality formation and contribute to the cultivation of grapes with higher nutritional value.
Article
Materials Science, Textiles
Xinbo Guo, Yixin Wu, Nan Xiang, Fangyang Gao, Caisheng Qiu
Summary: This study found that ultrasonic pretreatment significantly increased tocopherols, tocotrienols, and carotenoids in flax sprouts. The response to ultrasonic pretreatments varied among different varieties of flax sprouts, but the overall trend indicated that ultrasonic pretreatment could enhance the nutritional value of flax sprouts.
JOURNAL OF NATURAL FIBERS
(2022)
Article
Agriculture, Multidisciplinary
Bing Zhang, Tianxiang Wen, Nan Xiang, Yihan Zhao, Xinbo Guo
Summary: Ultrasonic pretreatment was found to increase the accumulation of tocopherols and carotenoids in maize seedlings but decrease tocotrienol synthesis. The carotenoid content reached its highest level at 8 minutes of ultrasonic pretreatment, while tocopherol initially dropped but began to rise after 8 minutes. The predominant component of tocochromanols in maize seedlings shifted from gamma-tocotrienol to alpha-tocopherol after ultrasonic pretreatment.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Review
Chemistry, Analytical
Lin Jiang, Hang Yang, Weiqi Cheng, Zhonghua Ni, Nan Xiang
Summary: Circulating tumor cells (CTCs) are important biomarkers in liquid biopsy, and their number and heterogeneity play a crucial role in cancer diagnosis and personalized medicine. However, due to their low abundance, conventional methods can only detect CTCs at the population level. Therefore, droplet microfluidics, as a high-throughput and sensitive single-cell analysis platform, becomes a significant tool for quantitative detection and heterogeneity analysis of CTCs.
Article
Biochemical Research Methods
Hang Yang, Lin Jiang, Kefan Guo, Nan Xiang
Summary: We developed a manually operated device based on a static droplet array (SDA) for the synthesis of nonspherical microparticles. The device utilized an improved SDA structure and reversible bonding between PDMS for large-scale synthesis and rapid extraction. We investigated the effects of flow rate, SDA well size, and shape on droplet generation and found that it was insensitive to flow rate. The device was capable of producing monodisperse droplets by manual pushing of the syringe. Additionally, we successfully integrated four different SDA structures in one device and achieved synthesis and extraction of nonspherical microparticles with various shapes and materials.
Review
Chemistry, Analytical
Yao Chen, Kefan Guo, Lin Jiang, Shu Zhu, Zhonghua Ni, Nan Xiang
Summary: Cell deformability plays a crucial role in cellular processes and functions, and its measurement at the single-cell level is highly sought after in biomedicine for various applications. Microfluidics has emerged as a promising tool for single-cell deformability analysis, offering advantages such as reduced complexity and reagent consumption. This review discusses recent advances in microfluidic technologies for single-cell deformability analysis, including different methods of stress generation and their respective applications, advantages, and disadvantages. Future research directions are also explored, such as improving detection performance and integration of detection technologies.
Article
Chemistry, Analytical
Nan Xiang, Zhonghua Ni
Review
Biochemical Research Methods
Shu Zhu, Yaohui Fang, Kefan Guo, Zhonghua Ni, Nan Xiang
Summary: Conventional cancer diagnosis requires invasive tissue biopsy, causing severe harm to patients. Liquid biopsy, with its minimal invasiveness, has shown potential for real-time cancer diagnosis but still cannot replace tissue biopsy in most settings. This paper discusses the challenges and limitations of existing liquid biopsy instruments, as well as the opportunities and future progression of next-generation tools. Ultimately, the goal is to integrate liquid biopsy into clinical workflows and establish it as a validated and reliable tool for cancer diagnosis.
Article
Chemistry, Multidisciplinary
Qinghua Wang, Chao Liu, Huixin Wang, Kai Yin, Zhongjie Yu, Taiyuan Wang, Mengqi Ye, Xianjun Pei, Xiaochao Liu
Summary: Oil pollution poses a significant threat to human health and the environment, leading to global concern. Therefore, developing simple and efficient oil-water separation techniques is crucial. In this study, a laser-heat surface treatment method was used to create superwetting copper foam, which exhibited extreme wetting properties for water and oil. This method showed high separation efficiency and repeatability, providing a convenient avenue for oil-water separation.
Article
Materials Science, Multidisciplinary
Nan Xiang, Lin Li, Hua Wang, Jiang Qian, Tonghua Wang
Summary: Graphene oxide-polyvinyl alcohol mixed matrix membranes were prepared on the surface of polysulfone membranes for the dehydration of alcohols through pervaporation. The concentration and size of graphene oxide nanosheets were found to affect the separation performance of the membranes.
JOURNAL OF MATERIALS SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Yao Chen, Chen Ni, Lin Jiang, Zhonghua Ni, Nan Xiang
Summary: An inertial multi-force deformability cytometry (IMFDC) is developed for high-throughput, high-accuracy, and high-applicability tumor cell mechanotyping. The IMFDC is able to evaluate the deformability of different cells and identify cell types. The multiple-parameters-based machine learning model achieves high discrimination accuracy and throughput. The IMFDC has important applications in clinical cancer diagnosis.
Article
Crystallography
Xiaochao Liu, Jingyue Luo, Wenhui Bao, Xianjun Pei, Qinghua Wang, Zhonghua Ni
Summary: By prefabricating micro-grooves on the steel plate surface using laser ablation, a high-quality mechanical interlock and metallurgical bonding can be achieved in Al/steel lap welding, thereby increasing the line load of the joint.
Article
Food Science & Technology
Yaoyao Cheng, Nan Xiang, Honglin Chen, Yihan Zhao, Lixia Wang, Xuzhen Cheng, Xinbo Guo
Summary: This study aimed to investigate the regulatory mechanisms of white, blue, and red lights on carotenoid and tocopherol biosynthesis in mung bean sprouts. Results showed that these lights stimulated the increase of carotenoids and tocopherols in sprouts, with the best yield observed under white light. Genes involved in carotenoid and tocopherol biosynthesis exhibited high expression levels under light quality conditions. These findings provide insights into light-mediated regulation and fortification of carotenoids and tocopherols, as well as guidance for future agricultural cultivation of mung bean sprouts.
FOOD CHEMISTRY: MOLECULAR SCIENCES
(2023)
Article
Chemistry, Analytical
Yao Chen, Lin Jiang, Xiaozhe Zhang, Zhonghua Ni, Nan Xiang
Summary: This article introduces an efficient label-free sorting and mechanical phenotyping method for tumor cells, which utilizes a viscoelastic-sorting integrated deformability cytometer (VSDC) to sort, extract, and analyze the mechanical properties of tumor cells. Machine learning algorithms are used to distinguish tumor cells from white blood cells.
ANALYTICAL CHEMISTRY
(2023)
Article
Biochemical Research Methods
Zheng Zhou, Chen Ni, Zhixian Zhu, Yao Chen, Zhonghua Ni, Nan Xiang
Summary: Cell mechanical properties can be used as label-free markers to indicate cell states and disease processes. This study proposes a high-throughput adjustable deformability cytometry system that combines three-dimensional elasto-inertial focusing and a virtual fluidic channel to enable fast mechanical phenotyping of various cell sizes.