Gene augmented nuclear-targeting sonodynamic therapy via Nrf2 pathway-based redox balance adjustment boosts peptide-based anti-PD-L1 therapy on colorectal cancer

A hybrid semiconducting organosilica-based O2 nanoeconomizer for on-demand synergistic photothermally boosted radiotherapy

(2021) Wei Tang et al.   Nature Communications

Cascade Catalytic Nanoplatform Based on “Butterfly Effect” for Enhanced Immunotherapy

(2021) Yanjiang Shao et al.   Advanced Healthcare Materials

Noninvasively immunogenic sonodynamic therapy with manganese protoporphyrin liposomes against triple-negative breast cancer

(2021) Huaqing Chen et al.   BIOMATERIALS

A sonosensitiser‐based polymeric nanoplatform for chemo‐sonodynamic combination therapy of lung cancer

(2021) Yanan Zhang et al.   JOURNAL OF NANOBIOTECHNOLOGY

Biomimetic oxygen delivery nanoparticles for enhancing photodynamic therapy in triple-negative breast cancer

(2021) Hanyi Fang et al.   JOURNAL OF NANOBIOTECHNOLOGY

Dual activity of PD-L1 targeted Doxorubicin immunoliposomes promoted an enhanced efficacy of the antitumor immune response in melanoma murine model

(2021) María Merino et al.   JOURNAL OF NANOBIOTECHNOLOGY

Endoplasmic Reticulum Targeting to Amplify Immunogenic Cell Death for Cancer Immunotherapy

(2020) Hongzhang Deng et al.   NANO LETTERS

Copper-Doped Nanoscale Covalent Organic Polymer for Augmented Photo/Chemodynamic Synergistic Therapy and Immunotherapy

(2020) Chunling Hu et al.   BIOCONJUGATE CHEMISTRY

Homologous-targeting biomimetic nanoparticles for photothermal therapy and Nrf2-siRNA amplified photodynamic therapy against oral tongue squamous cell carcinoma

(2020) Shurui Shi et al.   CHEMICAL ENGINEERING JOURNAL

Alarmin-painted exosomes elicit persistent antitumor immunity in large established tumors in mice

(2020) Bingfeng Zuo et al.   Nature Communications

Recent Advances in Hyperthermia Therapy‐Based Synergistic Immunotherapy

(2020) Mengyu Chang et al.   ADVANCED MATERIALS

Corn-like Au/Ag nanorod-mediated NIR-II photothermal/photodynamic therapy potentiates immune checkpoint antibody efficacy by reprogramming the cold tumor microenvironment

(2020) Liangjie Jin et al.   BIOMATERIALS

Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade

(2020) Shivani Srivastava et al.   CANCER CELL

V-TiO2 nanospindles with regulating tumor microenvironment performance for enhanced sonodynamic cancer therapy

(2020) Xianwen Wang et al.   Applied Physics Reviews

Reversing cold tumors to hot: An immunoadjuvant-functionalized metal-organic framework for multimodal imaging-guided synergistic photo-immunotherapy

(2020) Zhijin Fan et al.   Bioactive Materials

SIRT7-mediated ATM deacetylation is essential for its deactivation and DNA damage repair

(2019) Ming Tang et al.   Science Advances

Immunotherapy in colorectal cancer: rationale, challenges and potential

(2019) Karuna Ganesh et al.   Nature Reviews Gastroenterology & Hepatology

Mitochondria-Targeted and Ultrasound-Activated Nanodroplets for Enhanced Deep-Penetration Sonodynamic Cancer Therapy

(2019) Liang Zhang et al.   ACS Applied Materials & Interfaces

Combining Nanomedicine and Immunotherapy

(2019) Yang Shi et al.   ACCOUNTS OF CHEMICAL RESEARCH

Boosting Cancer Therapy with Organelle-Targeted Nanomaterials

(2019) peng gao et al.   ACS Applied Materials & Interfaces

Targeting photodynamic and photothermal therapy to the endoplasmic reticulum enhances immunogenic cancer cell death

(2019) Wei Li et al.   Nature Communications

Chondroitin Sulfate-Linked Prodrug Nanoparticles Target the Golgi Apparatus for Cancer Metastasis Treatment

(2019) Haohuan Li et al.   ACS Nano

Reversing tumor stemness via orally targeted nanoparticles achieves efficient colon cancer treatment

(2019) Jiaqi Xu et al.   BIOMATERIALS

Development and screening of brain-targeted lipid-based nanoparticles with enhanced cell penetration and gene delivery properties

(2019) Bruna dos Santos Rodrigues et al.   International Journal of Nanomedicine

Rationally designed peptide-conjugated gold/platinum nanosystem with active tumor-targeting for enhancing tumor photothermal-immunotherapy

(2019) Qian Yang et al.   JOURNAL OF CONTROLLED RELEASE

Nanoformulated Codelivery of Quercetin and Alantolactone Promotes an Antitumor Response through Synergistic Immunogenic Cell Death for Microsatellite-Stable Colorectal Cancer

(2019) Jing Zhang et al.   ACS Nano

Combination of Bacterial‐Photothermal Therapy with an Anti‐PD‐1 Peptide Depot for Enhanced Immunity against Advanced Cancer

(2019) Wenfei Chen et al.   ADVANCED FUNCTIONAL MATERIALS

Colorectal Peritoneal Metastases Treated by Perioperative Systemic Chemotherapy and Cytoreductive Surgery With or Without Mitomycin C-Based HIPEC: A Comparative Study Using the Peritoneal Surface Disease Severity Score (PSDSS)

(2019) Dario Baratti et al.   ANNALS OF SURGICAL ONCOLOGY

Discovery of low-molecular weight anti-PD-L1 peptides for cancer immunotherapy

(2019) Hao Liu et al.   Journal for ImmunoTherapy of Cancer

Smart Nanovesicle-Mediated Immunogenic Cell Death through Tumor Microenvironment Modulation for Effective Photodynamic Immunotherapy

(2019) Weijing Yang et al.   ACS Nano

Nucleus-targeting near-infrared nanoparticles based on TAT peptide-conjugated IR780 for photo-chemotherapy of breast cancer

(2019) Guoyun Wan et al.   CHEMICAL ENGINEERING JOURNAL

Immunogenic cell death induced by a new photodynamic therapy based on photosens and photodithazine

(2019) Victoria D. Turubanova et al.   Journal for ImmunoTherapy of Cancer

Nanoparticle-mediated Immunogenic Cell Death Enables and Potentiates Cancer Immunotherapy

(2018) Xiaopin Duan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Photodynamic therapy – mechanisms, photosensitizers and combinations

(2018) Stanisław Kwiatkowski et al.   BIOMEDICINE & PHARMACOTHERAPY

Co-administration of kla-TAT peptide and iRGD to enhance the permeability on A549 3D multiple sphere cells and accumulation on xenograft mice

(2018) Cuihua Hu et al.   Chemical Biology & Drug Design

TAT-conjugated chitosan cationic micelle for nuclear-targeted drug and gene co-delivery

(2018) Guan-Hai Wang et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Sequentially Responsive Therapeutic Peptide Assembling Nanoparticles for Dual-Targeted Cancer Immunotherapy

(2018) Keman Cheng et al.   NANO LETTERS

Synergistic and low adverse effect cancer immunotherapy by immunogenic chemotherapy and locally expressed PD-L1 trap

(2018) Wantong Song et al.   Nature Communications

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Measurement of Cyanine Dye Photobleaching in Photosensitizer Cyanine Dye Conjugates Could Help in Optimizing Light Dosimetry for Improved Photodynamic Therapy of Cancer

(2018) Nadine James et al.   MOLECULES

Nucleus-Targeted Organoiridium-Albumin Conjugate for Photodynamic Cancer Therapy

(2018) Pingyu Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pullulan-coated phospholipid and Pluronic F68 complex nanoparticles for carrying IR780 and paclitaxel to treat hepatocellular carcinoma by combining photothermal therapy/photodynamic therapy and chemotherapy

(2017) Dan Wang et al.   International Journal of Nanomedicine

Acidity-triggered TAT-presenting nanocarriers augment tumor retention and nuclear translocation of drugs

(2017) Wei Jiang et al.   Nano Research

A multifunctional nanoparticle system combines sonodynamic therapy and chemotherapy to treat hepatocellular carcinoma

(2017) Yang Liu et al.   Nano Research

Acidity-Triggered Tumor-Targeted Chimeric Peptide for Enhanced Intra-Nuclear Photodynamic Therapy

(2016) Kai Han et al.   ADVANCED FUNCTIONAL MATERIALS

Targeted iron oxide nanoparticles for the enhancement of radiation therapy

(2016) Anastasia K. Hauser et al.   BIOMATERIALS

The development and validation of a CT-based radiomics signature for the preoperative discrimination of stage I-II and stage III-IV colorectal cancer

(2016) Cuishan Liang et al.   Oncotarget

Recent advances of sonodynamic therapy in cancer treatment

(2016) Guo-Yun Wan et al.   Cancer Biology & Medicine

Self-assembled PEG-IR-780-C13 micelle as a targeting, safe and highly-effective photothermal agent for in vivo imaging and cancer therapy

(2015) Ahu Yuan et al.   BIOMATERIALS

Evaluation of acridine orange, LysoTracker Red, and quinacrine as fluorescent probes for long-term tracking of acidic vesicles

(2014) Agnieszka Pierzyńska-Mach et al.   CYTOMETRY PART A

Role of Nrf2 in Cancer Photodynamic Therapy: Regulation of Human ABC Transporter ABCG2

(2013) Toshihisa Ishikawa et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Nuclear-Targeted Drug Delivery of TAT Peptide-Conjugated Monodisperse Mesoporous Silica Nanoparticles

(2012) Limin Pan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Spheroid-based drug screen: considerations and practical approach

(2009) Juergen Friedrich et al.   Nature Protocols