Journal
JOURNAL OF BIOINFORMATICS AND COMPUTATIONAL BIOLOGY
Volume 19, Issue 6, Pages -Publisher
WORLD SCIENTIFIC PUBL CO PTE LTD
DOI: 10.1142/S0219720021400126
Keywords
Phylogenetic network; network generator; network topology
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Funding
- Netherlands Organization for Scientific Research (NWO) [639.072.602]
- Federal Government of Canada's Canada 150 Research Chair program
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Phylogenetic networks provide a more comprehensive representation of evolutionary history compared to phylogenetic trees, capturing natural reticulate evolutionary processes such as horizontal gene transfer and gene recombination. Stochastic processes for generating random trees or networks are essential tools in evolutionary analysis, particularly in phylogeny reconstruction.
Phylogenetic networks represent evolutionary history of species and can record natural reticulate evolutionary processes such as horizontal gene transfer and gene recombination. This makes phylogenetic networks a more comprehensive representation of evolutionary history compared to phylogenetic trees. Stochastic processes for generating random trees or networks are important tools in evolutionary analysis, especially in phylogeny reconstruction where they can be utilized for validation or serve as priors for Bayesian methods. However, as more network generators are developed, there is a lack of discussion or comparison for different generators. To bridge this gap, we compare a set of phylogenetic network generators by profiling topological summary statistics of the generated networks over the number of reticulations and comparing the topological profiles.
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