Interferon Gamma-Inducible Protein 16 of Peripheral Blood Mononuclear Cells May Sense Hepatitis B Virus Infection and Regulate the Antiviral Immunity

Nuclear Sensor IFI 16 Inhibits the Function of HBV ccc DNA by Integrating Innate Immune Activation and Epigenetic Suppression

(2019) Yuanyuan Yang et al.   HEPATOLOGY

Restoring, releasing or replacing adaptive immunity in chronic hepatitis B

(2019) Mala K. Maini et al.   Nature Reviews Gastroenterology & Hepatology

IFI16 is involved in HBV-associated acute-on-chronic liver failure inflammation

(2018) Xiuqing Pang et al.   BMC GASTROENTEROLOGY

Hepatitis B Virus Does Not Interfere With Innate Immune Responses in the Human Liver

(2018) Aleksei Suslov et al.   GASTROENTEROLOGY

HBV Bypasses the Innate Immune Response and Does Not Protect HCV From Antiviral Activity of Interferon

(2018) Pascal Mutz et al.   GASTROENTEROLOGY

Mechanisms of Hepatitis B Virus Persistence

(2018) Kuen-Nan Tsai et al.   TRENDS IN MICROBIOLOGY

Lack of immunological DNA sensing in hepatocytes facilitates hepatitis B virus infection

(2016) Martin K. Thomsen et al.   HEPATOLOGY

Regulation of chronic inflammatory and immune processes by extracellular vesicles

(2016) Paul D. Robbins et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular characterization of woodchuck IFI16 and AIM2 and their expression in woodchucks infected with woodchuck hepatitis virus (WHV)

(2016) Qi Yan et al.   Scientific Reports

The cyclic GMP-AMP synthetase-STING signaling pathway is required for both the innate immune response against HBV and the suppression of HBV assembly

(2015) Hiromichi Dansako et al.   FEBS Journal

Early inhibition of hepatocyte innate responses by hepatitis B virus

(2015) Souphalone Luangsay et al.   JOURNAL OF HEPATOLOGY

Herpesvirus Genome Recognition Induced Acetylation of Nuclear IFI16 Is Essential for Its Cytoplasmic Translocation, Inflammasome and IFN-β Responses

(2015) Mairaj Ahmed Ansari et al.   PLoS Pathogens

Interferon γ-inducible Protein (IFI) 16 Transcriptionally Regulates Type I Interferons and Other Interferon-stimulated Genes and Controls the Interferon Response to both DNA and RNA Viruses

(2014) Mikayla R. Thompson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Constitutive Interferon-Inducible Protein 16-Inflammasome Activation during Epstein-Barr Virus Latency I, II, and III in B and Epithelial Cells

(2013) M. A. Ansari et al.   JOURNAL OF VIROLOGY

Innate and adaptive immune responses in chronic hepatitis B virus infections: towards restoration of immune control of viral infection

(2011) Antonio Bertoletti et al.   GUT

Characterization of microRNA expression profiles associated with hepatitis B virus replication and clearance in vivo and in vitro

(2011) Xiao-Ben Pan et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Hepatitis B virus polymerase inhibits RIG-I- and Toll-like receptor 3-mediated beta interferon induction in human hepatocytes through interference with interferon regulatory factor 3 activation and dampening of the interaction between TBK1/IKK  and DDX3

(2010) S. Yu et al.   JOURNAL OF GENERAL VIROLOGY

IFI16 is an innate immune sensor for intracellular DNA

(2010) Leonie Unterholzner et al.   NATURE IMMUNOLOGY

Temporal Analysis of Early Immune Responses in Patients With Acute Hepatitis B Virus Infection

(2009) Claire Dunn et al.   GASTROENTEROLOGY

Hepatitis B virus suppresses toll-like receptor-mediated innate immune responses in murine parenchymal and nonparenchymal liver cells

(2008) Jun Wu et al.   HEPATOLOGY