Article
Biology
Khalid Mashai Alanazi, Ahmed Ali Al-kawmani, Mohammad Abul Farah, Waleed Ali Hailan, Ali Alsalme, Nabil Al-Zaqri, M. Ajmal Ali, Abobakr Mahmood Almansob
Summary: The study investigated the preventative role of zinc nanoparticles biosynthesized by Ochradenus arabicus leaf extracts in limiting genotoxicity and cytotoxicity caused by indole acetic acid in laboratory mice. The results showed that treatment with OAZnO NPs ameliorated IAA-induced cytotoxic damage in mice, with no toxicity observed from exposure to OAZnO NPs alone. Further mechanistic and in vitro studies are needed to confirm these findings.
SAUDI JOURNAL OF BIOLOGICAL SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Suzan Attia Mawed, Carlotta Marini, Mahmoud Alagawany, Mayada R. Farag, Rasha M. Reda, Mohamed T. El-Saadony, Walaa M. Elhady, Gian E. Magi, Alessandro Di Cerbo, Wafaa G. El-Nagar
Summary: This study elucidated the ultrastructure changes in the ovary in response to exposure to zinc oxide nanoparticles (ZnO-NPs) and explored the role of autophagy and apoptosis in the fertility of female zebrafish. The results showed that ZnO-NPs induced cytotoxicity, oxidative stress, and necroptosis, leading to a reduction in the fecundity of female zebrafish.
Article
Biochemistry & Molecular Biology
Ibrahim M. M. Alhazza, Iftekhar Hassan, Hossam Ebaid, Jameel Al-Tamimi, Zafrul Hasan
Summary: This study investigates the therapeutic potential of zinc oxide nanoparticles (ZnO NPs) against potassium bromate (PB)-induced nephrotoxicity in Swiss albino rats, and the results demonstrate the significant ameliorative efficacy of ZnO NPs in treating PB-induced kidney toxicity.
Article
Biotechnology & Applied Microbiology
Ana Itsel Canales-Mendoza, Maricela Villanueva-Ibanez, Xochilt Tovar-Jimenez, Jorge Alvarez-Cervantes
Summary: The utilization of nanoparticles in agriculture requires a positive and environmentally friendly response, as well as a better understanding of their impact on plant cultures. This study investigated the effects of biosynthesized zinc oxide nanoparticles (ZNPs) on the multiplication stage of Agave salmiana var. Ayoteco shoots. The introduction of ZNPs resulted in organogenesis and optimal shoot production in Agave seedlings. Depending on the treatment, the combination of nanoparticles and growth regulators caused modifications in shoot and seedling structures, particularly in stomata, without ZnO accumulation. The antioxidant activity of the shoots and seedlings varied depending on the stressors they were exposed to, including growth regulators and nanoparticles.
PLANT CELL TISSUE AND ORGAN CULTURE
(2023)
Article
Biology
Ghasem Rahimi, Kalateh Shah Mohammad, Mahsa Zarei, Mohammad Shokoohi, Ehsan Oskoueian, Mahsa Rastegar Moghaddam Poorbagher, Ehsan Karimi
Summary: This study aimed to synthesize zinc oxide nanoparticles (ZnO-NPs) and evaluate their safety in mice. The results showed that supplementation with 50 mg/kg or higher concentrations of ZnO-NPs might be toxic to mice.
BIOLOGICAL RESEARCH
(2022)
Article
Food Science & Technology
Zhanhang Wang, Shujuan Liu, Xiaolong Xu, Yuxuan Song, Lei Zhang, Xiaopeng An
Summary: This study used RNA-seq analysis to evaluate the potential toxicity of zinc oxide nanoparticles (ZnO NPs) on goat mammary epithelial cells (GMECs) in vitro. The results showed that ZnO NP treatment significantly reduced GMEC viability in a time- and dose-dependent manner. Additionally, ZnO NP exposure altered the expression levels of genes associated with mitochondrial dysfunction, oxidative stress, apoptosis pathways, endoplasmic reticulum stress, and autophagy. These findings highlight the significant toxic effects of ZnO NPs on GMECs and the need for cautious use in the feed and food industry. Furthermore, RNA-seq represents a promising method for assessing the toxicity mechanisms of nanomaterials.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Chemistry, Multidisciplinary
Yen-Ling Lee, Yung-Sheng Shih, Zi-Yu Chen, Fong-Yu Cheng, Jing-Yu Lu, Yuan-Hua Wu, Ying-Jan Wang
Summary: This study investigated the effects of silver nanoparticles and zinc oxide nanoparticles on zebrafish embryos in aquatic environments. The research found that spiking these nanoparticles into natural water samples had a toxic effect on the embryos, with the level of toxicity influenced by complex components in the water. Additionally, zinc oxide nanoparticles caused a delay in embryo hatching. Measurement of reactive oxidative stress levels, apoptosis, and autophagy revealed the interaction and toxicity mechanisms of the nanoparticles with the embryos.
Article
Chemistry, Multidisciplinary
Ankita Nandi, Ritam Mehera, Moumita Mandal, Paramesh Chandra, Swapan K. Mandal, Naznin Ara Begum, Chandan K. Jana, Nilanjana Das
Summary: In this study, stable biogenic ZnO nanoparticles were successfully synthesized using a biosynthesis method, and their effects on oxidative stress parameters in Saccharomyces cerevisiae were investigated. The results demonstrate that high concentrations of ZnO nanoparticles may induce oxidative stress conditions, suggesting caution in their extensive use.
JOURNAL OF PHYSICS AND CHEMISTRY OF SOLIDS
(2024)
Article
Biochemistry & Molecular Biology
Varsha Rani, Yeshvandra Verma, S. V. S. Rana
Summary: Results of the study show that treatment with ZnONPs in rats treated with DMN reduced the levels of malonaldehyde, H2O2, and NO in the kidney, while increasing GSH concentration. Additionally, the antioxidative effects of ZnONPs were supported by the activity of glutathione S-transferase and glutathione peroxidase.
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
(2022)
Review
Materials Science, Biomaterials
Sheikh Tanzina Haque, Subbroto Kumar Saha, Md. Enamul Haque, Nirupam Biswas
Summary: Nanotechnology-based platforms show promising potential in deciphering the biological environment and offering personalized treatment methods for wound healing. Studies have demonstrated their essential role in influencing skin repair mechanisms.
BIOMATERIALS SCIENCE
(2021)
Article
Agriculture, Dairy & Animal Science
Sheren A. Al-Zahaby, Mayada R. Farag, Mahmoud Alagawany, Heba S. A. Taha, Maria Vittoria Varoni, Giuseppe Crescenzo, Suzan Attia Mawed
Summary: Zinc oxide nanoparticles can induce toxic effects on the olfactory epithelium of fish, impairing cellular repairing mechanisms and causing malformations in the olfactory rosettes, which in turn affects fish smell and appetite.
Article
Environmental Sciences
Halina Falfushynska, Fangli Wu, Eugene P. Sokolov, Inna M. Sokolova
Summary: Zinc oxide nanoparticles (nZnO) released into marine environments can have ecotoxicological effects, but their interaction with other stressors like salinity fluctuations in marine organisms is poorly understood. To assess this, a study was conducted on blue mussels exposed to nZnO and different salinity regimes for 21 days. The results showed that nZnO and dissolved Zn had different effects on oxidative stress, detoxification, and apoptosis biomarkers, but similar effects on metallothioneins and inflammatory markers. The study also found that the cellular toxicity of nZnO was influenced by salinity, with higher stress observed at normal and fluctuating salinity conditions compared to low salinity conditions.
MARINE ENVIRONMENTAL RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
Prashant B. Chouke, Ajay K. Potbhare, Nitin P. Meshram, Manoj M. Rai, Kanhaiya M. Dadure, Karan Chaudhary, Alok R. Rai, Martin F. Desimone, Ratiram G. Chaudhary, Dhanraj T. Masram
Summary: This study demonstrates the green fabrication of nickel oxide nanoparticles using Cleome simplicifolia and investigates their in vitro toxicity in Bm-17 and Labeo rohita liver cells. The bioinspired NiO NPs were characterized and shown to have a crystalline structure. The toxic effects of NiO NPs were evaluated in cells, and it was found that higher concentrations resulted in more severe toxicity. Similar effects were observed in Labeo rohita liver cells.
Article
Environmental Sciences
Marwa E. Hassan, Rasha R. Hassan, Kawthar A. Diab, Aziza A. El-Nekeety, Nabila S. Hassan, Mosaad A. Abdel-Wahhab
Summary: This study evaluated the protective role of encapsulated thyme oil against zinc oxide nanoparticles, showing that encapsulated thyme oil could alleviate oxidative stress and other disturbances induced by ZnO-NPs.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Chemistry, Physical
Hassan O. Shaikhaldein, Fahad Al-Qurainy, Mohammad Nadeem, Salim Khan, Mohamed Tarroum, Abdalrhaman M. Salih, Saleh Alansi, Abdulrahman Al-Hashimi, Alanoud Alfagham, Jawaher Alkahtani
Summary: This study examines the effects of biosynthesized silver nanoparticles on salt-stressed Maerua oblongifolia plants and finds that these nanoparticles can alleviate the adverse effects of salt stress and improve plant growth and antioxidant defense systems.
Article
Biochemistry & Molecular Biology
Norah S. Alfarraj, Mohamed Tarroum, Fahad Al-Qurainy, Mohammad Nadeem, Salim Khan, Abdalrhaman M. Salih, Hassan O. Shaikhaldein, Abdulrahman Al-Hashimi, Saleh Alansi, Kahkashan Perveen
Summary: In this study, silver nanoparticles (AgNPs) were successfully synthesized using the leaf extract of Hibiscus tiliaceus, offering an environmentally friendly, economical, and simple approach for nanomaterial synthesis. The AgNPs exhibited absorption at 415 nm and were characterized using various techniques. Furthermore, the AgNPs showed significant antibacterial and antifungal activity, as well as promoting callus growth in plant tissue culture.
Article
Engineering, Chemical
Aqsa Aziz, Mushtaq Ahmad, Muhammad Zafar, Abdel-Rhman Z. Gaafar, Mohamed S. Hodhod, Shazia Sultana, Mohammad Athar, Fethi Ahmet Ozdemir, Trobjon Makhkamov, Akramjon Yuldashev, Oybek Mamarakhimov, Maxsuda Nizomova, Salman Majeed, Bisha Chaudhay
Summary: The study focused on the synthesis of copper oxide phyto-nanocatalyst using non-edible Citrullus colocynthis as a new renewable feedstock. Under optimized conditions, the maximum biodiesel yield of 95% was achieved. The synthesized phyto-nanocatalyst showed high efficiency and stability, even after being reused five times, thus proving to be a promising alternative for the future biodiesel industry.
Article
Chemistry, Inorganic & Nuclear
Jaouad Bensalah, Hanae Ouaddari, Saban Erdogan, Burak Tuzun, Abdel-Rhman Z. Gaafar, Hiba-Allah Nafidi, Mohammed Bourhia, Amar Habsaoui
Summary: Adsorption of multivalent heavy metals using the cationic resin polymer A(R)IRC-50 as the organic adsorbent was studied in this research. The experimental results showed that the cationic polymer had a high adsorption capacity for Cr(III), Cu(II), and Ag(I) ions. The adsorption kinetics followed the pseudo-second-order model and the adsorption isotherms were well-described by the Freundlich model. The adsorption process was found to be spontaneous and endothermic.
INORGANIC CHEMISTRY COMMUNICATIONS
(2023)
Article
Biochemistry & Molecular Biology
Fozia Batool, Samia Kanwal, Hafsa Kanwal, Sobia Noreen, Mohamed S. Hodhod, Muhammad Mustaqeem, Gulnaz Sharif, Hafiza Komal Naeem, Javeria Zahid, Abdel-Rhman Z. Gaafar
Summary: This study explores the potential of rice husks coated with iron oxide for efficient Acid Blue 25 decontamination. Various models and analytical techniques were used to analyze the adsorption process and parameters. The findings suggest practical applications of this method in wastewater treatment and environmental remediation.
Article
Plant Sciences
Tahrim Ramzan, Muhammad Shahbaz, Muhammad Faisal Maqsood, Usman Zulfiqar, Rafia Urooj Saman, Nian Lili, Muhammad Irshad, Sana Maqsood, Arslan Haider, Babar Shahzad, Abdel-Rhman Z. Gaafar, Fasih Ullah Haider
Summary: This study aimed to evaluate the effects of phenylalanine (PA) on mustard plants under drought stress. The results showed that foliar application of PA helped to overcome the losses caused by drought and improved the shoot length, chlorophyll contents, and yield of mustard plants. It also reduced oxidative damage and electrolyte leakage. However, further research is needed to examine the impacts of PA on open-field-grown mustard crops.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2023)
Article
Environmental Sciences
Sara Khan, Shabnam Dilawar, Said Hassan, Amin Ullah, Humaira Yasmin, Tehreem Ayaz, Fazlullah Akhtar, Abdel-Rhman Z. Gaafar, Selvam Sekar, Sadia Butt
Summary: This study investigated the pollution load of heavy metals in sediment and wastewater in an industrial estate in Pakistan and compared the ability of two native grass species, Cynodon dactylon and Digiteria sanguinalis, to accumulate these metals. The results showed that phytoremediation using these grass species is an eco-friendly and cost-effective method for soil remediation.
Article
Green & Sustainable Science & Technology
Fatma Bibi, Asifa Hameed, Noor Muhammad, Khurram Shahzad, Iftikhar Ahmad, Tawaf Ali Shah, Abdel-Rhman Z. Gaafar, Mohamed S. Hodhod, Mohammed Bourhia, Hiba-Allah Nafidi
Summary: In treating mango Chaunsa plants affected by dieback disease, the application of poultry litter + NPK treatment effectively reduced disease intensity. The experimental results of the past two years showed that compared to NPK alone, the poultry litter + NPK treatment reduced disease intensity by 20% and 50% in the second and third years, respectively.
Article
Green & Sustainable Science & Technology
Kashif Bashir, Sara Khan, Ramzan Ali, Humaira Yasmin, Abdel-Rhman Z. Gaafar, Fazal E. Azeem Khilgee, Sadia Butt, Amin Ullah
Summary: Aquatic pollution caused by urbanization and industrialization has become a pressing issue. This study focuses on the remediation of industrial wastewater using a consortium of microorganisms, including Bacillus pakistanensis, Lysinibacillus composti, and Cladophora glomerata. The results demonstrate significant reductions in various pollutants, indicating the effectiveness of the algae-bacteria consortium for bioremediation.
Article
Multidisciplinary Sciences
Mandapelli Sharath Chandra, R. K. Naresh, Rajan Bhatt, Praveen Kadam, Manzer H. Siddiqui, Abdel-Rhman Z. Gaafar, Md Atikur Rahman
Summary: Compared to conventional cultivation methods, conservation tillage has shown better performance in paddy production systems, and combining organic and inorganic fertilizers can increase rice yield and improve soil health.
Article
Biotechnology & Applied Microbiology
Mohammad Saleem Dar, Mushtaq Ahmad, Nakeeb-Un-Nisa Yetoo, Bhagyshree Bhatt, Suhail Nazir Bhat, Heena Altaf, Sumira Rafiqee, Asha Nabi, F. A. Mohiddin, Abdel-Rhman Z. Gaafar, Sheikh Mansoor, Mehraj D. D. Shah, Muntazir Mushtaq
Summary: Apple scab caused by Venturia inaequalis causes significant damage to apple fruit production. A study investigated the evolutionary potential and population genetics of V. inaequalis using 132 isolates from five apple orchards. The study found diverse populations with variations in genetic differentiation and gene flow between populations. Host specialization was also observed, with three major clusters identified. These findings highlight the genotypic diversity and population genetic structure of V. inaequalis.
Article
Biochemistry & Molecular Biology
Mohamed Tarroum, Norah S. Alfarraj, Fahad Al-Qurainy, Abdulrahman Al-Hashimi, Salim Khan, Mohammad Nadeem, Abdalrhaman M. Salih, Hassan O. Shaikhaldein
Summary: The implementation of nanotechnology in plant tissue culture has significant effects on in vitro plant growth, development, and biosynthesis of secondary metabolites. This study investigated the impact of zinc oxide nanoparticles (ZnONPs) on the growth and phytochemical profiles of Delonix elata calli. Results showed that adding 30 mg/L of ZnONPs to the culture medium resulted in the highest callus fresh weight and increased accumulation of phenolic and flavonoid compounds.
Article
Chemistry, Multidisciplinary
Zineb El Kerdoudi, Jaouad Bensalah, Nouhaila Ferraa, Abdelali El Mekkaoui, Avni Berisha, Zaki Safi, Hanae Ouaddari, Farid Khallouki, Musaab Dauelbait, Hiba-Allah Nafidi, Abdel-Rhman Z. Gaafar, Mohammed Bourhia, Amar Habsaoui, Nouredine El Mejdoub
Summary: By studying the characteristics of natural clay and the kinetic models of dye adsorption, this research provides insights into an ideal adsorption system. The results reveal that the natural clay is composed of various mineral substances, and the adsorption process of the dye is better described by a second-order kinetic model. Quantum descriptor analysis suggests strong interactions between the dye and the clay. Moreover, thermodynamic parameters indicate that the dye adsorption process on the clay is spontaneous and exothermic.
Article
Biology
Muhammad Azhar Jameel, Muhammad Sajid Nadeem, Shiekh Marifatul Haq, Iqra Mubeen, Arifa Shabbir, Shahzad Aslam, Riyaz Ahmad, Abdel-Rhman Z. Gaafar, Bander M. A. Al-Munqedhi, Rainer W. Bussmann
Summary: This study used MaxEnt modeling to assess the habitat suitability of Tragopan melanocephalus in the Western Himalayas and identified ten influential drivers. The study found patchy distribution of suitable habitats throughout the Western Himalayas, with strips of highly suitable habitats along certain regions. The study also observed potential increase in habitat suitability under future climate change scenarios, but further research is needed to prevent population declines and identify causes of regional extinction. The findings suggest the importance of designating suitable areas as nature reserves to conserve biodiversity and reduce risks under changing climatic conditions.
Article
Pharmacology & Pharmacy
Tanzeela Amanat, Muhammad Usman Tariq, Hafiz Ahmad Sami, Hasan Shujah, Samreen Tahir, Hasnat Shabbir, Kinga Kasperkiewicz, Abdel-Rhman Z. Gaafar, Mohamed S. Elshikh
Summary: The study examined the impact of muesli on postprandial blood glucose levels in 15 healthy females and 15 diabetic females. Muesli was found to gradually increase blood sugar levels and limit glucose absorption. Its nutritional profile included 202 kcal energy, 32.7g carbohydrates, 9g fiber, 12.4g protein, and 2.5g fats. Muesli was shown to be effective in managing blood glucose levels in both healthy and diabetic populations.
PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2023)
Article
Plant Sciences
Saleem Ur Rahman, Ghulam Raza, Rubab Zahra Naqvi, Evan McCoy, Muhammed Hammad, Peter LaFayette, Wayne Allen Parrott, Imran Amin, Zahid Mukhtar, Abdel-Rhman Z. Gaafar, Mohamed S. Hodhod, Shahid Mansoor
Summary: This study reports the identification of resistant soybean germplasm and a novel mutation linked with disease susceptibility in yellow mosaic disease (YMD), a major constraint to soybean production in Pakistan. A highly resistant soybean line named NBG-SG Soybean was found, along with several highly susceptible soybean germplasm. The findings suggest the potential for starting soybean breeding programs for YMD resistance.
FRONTIERS IN PLANT SCIENCE
(2023)