Article
Electrochemistry
Fernando Otero, Kim Shortall, Urszula Salaj-Kosla, Syed A. M. Tofail, Edmond Magner
Summary: An electrochemical biosensor was developed using a hairpin DNA probe labeled with methylene blue for detecting the TP53 gene. The biosensor could selectively detect a single nucleotide polymorphism in the TP53 gene affecting residue 175 of the p53 protein, with a more pronounced response at shorter hybridization times.
ELECTROCHIMICA ACTA
(2021)
Review
Chemistry, Multidisciplinary
Changpeng Hu, Rabia Tahir, Hanbin Mao
Summary: Single-molecule mechanochemical sensing is a novel biosensing technique that uses mechanical force as a signal transduction mechanism. By converting the chemical binding of analyte molecules to mechanical signals, this technique allows for sensitive sensing at the single molecule level. Compared to traditional ensemble sensing methods, single-molecule mechanochemical sensing offers higher material efficiency and temporal resolution.
ACCOUNTS OF CHEMICAL RESEARCH
(2022)
Article
Chemistry, Analytical
Guanyu Chen, Ning Yang, Lilan Xu, Shi Lu, Zhuhua Chen, Fang Wu, Jinghua Chen, Xi Zhang
Summary: Electrochemical DNA (E-DNA) biosensors based on interface-mediated hybridization reactions are promising for point-of-care testing (POCT). This study proposes a base-stacking-driven catalytic hairpin assembly (BDCHA) nucleic acid amplification strategy for POCT. The strategy improves recycling efficiency by increasing the thermodynamic stability of the product and addresses steric hindrance limitation by minimizing DNA secondary structure formation or intertwining at the electrode surface. The introduced base-stacking effect makes the electrode serve as a booster, resulting in an increased reaction rate compared to conventional catalytic hairpin assembly.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Hui Xi, Hanlin Jiang, Mario Juhas, Yang Zhang
Summary: Noncanonical G-quadruplex nucleic acid structures have been used as probes in biosensors for accurate and efficient detection of metal ions, proteins, and nucleic acids. In this study, a reliable and efficient fluorescent biosensor platform for G-quadruplex based detection of the human AGT protein was constructed using the magnetic bead enrichment method. This biosensor provides high accuracy, speed, and low cost, and successfully detected AGT at the cellular level.
Article
Chemistry, Multidisciplinary
Shiwu Liu, Longzhi Tian, Qizhi He, Xiaoqi Wang, Jue Hu, Ling Li, Fangguo Lu, Yi Ning
Summary: This paper presents a fluorometric graphene oxide (GO)-based assay for quantifying agrB gene transcription in methicillin-resistant Staphylococcus aureus (MRSA). The assay utilizes exonuclease III (Exo III)-assisted target recycling and hybridization chain reaction (HCR) to achieve high sensitivity and selectivity. The method involves the cleavage of a hairpin DNA probe (HP1), followed by autonomous generation of a new trigger probe (TP) and subsequent HCR to produce a double-stranded DNA (dsDNA) product. This study demonstrates the potential of the assay for monitoring biofilm formation and studying drug action mechanisms.
NEW JOURNAL OF CHEMISTRY
(2023)
Review
Chemistry, Multidisciplinary
Goeun Park, Hanbin Park, Sang-Chan Park, Moonbong Jang, Jinho Yoon, Jae-Hyuk Ahn, Taek Lee
Summary: Zika virus (ZIKV) and dengue virus (DENV) infections are becoming more common due to global warming. Accurate diagnosis is essential for controlling these viral infections. Recent research has focused on developing biosensors for the accurate diagnosis of ZIKV and DENV using DNA nanotechnology. These biosensors offer advantages over traditional diagnostic methods, such as PCR and ELISA. DNA can serve as a bioreceptor and be easily modified with functional groups, making it a valuable tool for the development of specific bioreceptors that bind to viral proteins or nucleic acids. This review discusses advances in DNA-nanotechnology-based biosensors for the detection of ZIKV and DENV.
Article
Multidisciplinary Sciences
Subash C. B. Gopinath, Santheraleka Ramanathan, Suresh Chinni, Vicneswarry Dorairaj, Thangavel Lakshmipriya
Summary: Nonprotein coding RNA (npcRNA) is a transcribed gene sequence that cannot translate into protein but plays a specific role in modulation and regulation mechanisms. This study developed a highly specific and sensitive chromatographic assay using gold nanoparticles (AuNPs) to detect the presence of the npcRNA Sau-02 gene, which is specifically present in Staphylococcus aureus and methicillin-resistant S. aureus. The hybridization between Sau-02 npcRNA gene sequences was detected through the aggregation of AuNPs in salt solution, in the presence of probe-target gene sequences.
SCIENTIFIC REPORTS
(2022)
Article
Biophysics
Ssu-Chia Chen, Kuan-Ting Chen, Amily Fang-Ju Jou
Summary: The novel dual-amplification-boosted electrochemical biosensor was developed for detecting pancreatic cancer-associated miR-196b, showing a detection limit of 0.26 pM and nice analytical reproducibility. The biosensor offers great promise as a complementary tool for real sample detection in the clinic.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Electrochemistry
Xinya Jiang, Huijun Wang, Fang Yang, Li Cheng, Cai Nie, Wenbing Shi
Summary: In this study, an electrochemiluminescence (ECL) biosensor based on interparticle DNA walker and N-Ti3C2 QDs was developed for sensitive assay of MUC1. The interparticle DNA walker could improve the conversion efficiency of target MUC1 by enhancing its moving freedom and area. The synthesized N-Ti3C2 QDs showed higher ECL luminous efficiency compared to previous reported N-Ti3C2 QDs, providing a potential feasible method for other protein sensitive assay.
ELECTROCHIMICA ACTA
(2023)
Article
Chemistry, Multidisciplinary
Wenzhuo Wang, Wei Yuan, Debao Wang, Xutao Mai, Daoying Wang, Yongzhi Zhu, Fang Liu, Zhilan Sun
Summary: This research proposes a dual-mode sensing platform for the rapid and ultrasensitive detection of Clostridium perfringens, which utilizes the synergy between fluorescent and electrochemical signals to improve the sensitivity and accuracy of detection. The method showed excellent analytical performance, detecting C. perfringens at concentrations as low as 1 CFU g(-1) in real samples.
Article
Chemistry, Multidisciplinary
Hua Zhang, Yajuan Zhou, Dan Luo, Jingjian Liu, E. Yang, Guangyi Yang, Guangjun Feng, Qinhua Chen, Lun Wu
Summary: The study developed a fluorescence aptasensor for the detection of tumor-related exosomes, utilizing magnetic nanoparticles for capture and specific aptamer recognition. The sensor showed good linearity, low detection limit, and high specificity for tumor-related exosomes, demonstrating its potential for practical application in biological samples.
Article
Chemistry, Analytical
Shao-Hua Wen, Hengyuan Zhang, Sha Yu, Junping Ma, Jun-Jie Zhu, Yuanzhen Zhou
Summary: A novel COF/MB@MnO2 composite with abundant signal loading, specific recognition unit, and robust oxidase-like activity was successfully prepared for the detection of organophosphorus pesticides. The composite served as a dual-mode sensing platform, allowing electrochemical and photothermal measurements, and exhibited excellent performance in detecting OPs in complex environmental and food samples.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Ausra Valiuniene, Gabija Kavaliauskaite, Povilas Virbickas, Arunas Ramanavicius
Summary: An impedimetric urea biosensor was developed in this study by modifying a fluorine doped tin oxide coated glass slide with a layer of PB and immobilizing urease. The biosensor exhibited good sensitivity to urea and a linear detectable concentration range, with investigations into the optimal conditions for stabilizing the PB layer also conducted.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2021)
Article
Biophysics
Ya Bin Cui, Hang Yan, Zhe Sun, Yu Ling, Hong Qun Luo, Nian Bing Li
Summary: Researchers have designed a bipedal DNA walker with multiple recognition sites, which undergoes a transition from dumbbell-shaped DNA nanostructure to an annular bipedal DNA walker. This design enables dual amplification of the signal and achieves ultrasensitive photoelectrochemical (PEC) detection of circulating tumor DNA (ctDNA).
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Biophysics
Skomantas Serapinas, Justina Gineityte, Marius Butkevicius, Rapolas Danilevicius, Marius Dagys, Dalius Ratautas
Summary: This paper presents a new bioelectronic device for the detection of nuclease activity in various fluids. The developed sensor enables rapid and sensitive determination of DNase activity, with high accuracy and reproducibility demonstrated in real human saliva samples. The technology has the potential to improve nuclease quality control processes in the pharmaceutical/biotechnology industry and provide new insights into the importance of nucleases for medical applications.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Microbiology
Elham Kazemi, Vahideh Tarhriz, Mohammad Ali Amoozegar, Mohammad Saeid Hejazi
Summary: A novel slightly halophilic bacterium, Halomonas azerbaijanica, was isolated from Urmia Lake in Iran. It thrives in high salinity, moderate temperatures, and neutral pH conditions, belonging to the genus Halomonas.
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
(2021)
Article
Cell & Tissue Engineering
Parisa Nikasa, Tine Tricot, Nejat Mahdieh, Hossein Baharvand, Mehdi Totonchi, Mohammad Saeid Hejazi, Catherine M. Verfaillie
Summary: Autosomal recessive hypercholesterolemia (ARH) is a rare monogenic disorder caused by pathogenic variants in the LDLRAP1 gene, leading to variable responses to treatment. Patient-specific iPSC-derived hepatocyte-like cells have been validated as an appropriate tool to model ARH disease, providing insights into LDLRAP1 mutations and protein function.
STEM CELLS AND DEVELOPMENT
(2021)
Review
Immunology
Mohammad Ali Zolfaghari, Reza Arefnezhad, Forough Parhizkar, Mohammad Saeid Hejazi, Farhad Motavalli Khiavi, Ata Mahmoodpoor, Mehdi Yousefi
Summary: This review explores the dysregulation of cytokines produced from T cells, the imbalance of transcription factors of Th cells, the expression of chemokine receptors on T cells, as well as the dysregulation of various miRNAs related to T cells, which may contribute to the development of preeclampsia.
AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
(2021)
Article
Microbiology
Ruan Wenting, Soheila Montazersaheb, Shehzad Abid Khan, Hyung Min Kim, Vahideh Tarhriz, Mohammad Amin Hejazi, Mohammad Saeid Hejazi, Che Ok Jeon
Summary: TBZ9(T) is a novel moderately halophilic bacterium isolated from Urmia Lake in Iran, belonging to the genus Halomonas. It shows optimal growth at 3% salt concentration, 30 degrees Celsius temperature, and pH 7.0.
CURRENT MICROBIOLOGY
(2021)
Article
Immunology
Mohammad Ali Zolfaghari, Roza Motavalli, Mohammad Sadegh Soltani-Zangbar, Forough Parhizkar, Shahla Danaii, Leili Aghebati-Maleki, Mohammad Noori, Sanam Dolati, Majid Ahmadi, Hossein Samadi Kafil, Farhad Jadidi-Niaragh, Javad Ahmadian Heris, Ata Mahmoodpoor, Mohammad Saeid Hejazi, Mehdi Yousefi
Summary: The study revealed that in patients with preeclampsia, the expression level of miRNA-326 in CD4(+) cells increased, leading to the inhibition of Ets-1, a negative regulator of Th17 cell development. Additionally, the number and expression level of Th17 cells and transcription factor ROR gamma t increased, while Treg cells and transcription factor Foxp3 showed a decrease. Flow cytometry analysis indicated an increase in the Th17/Treg ratio, along with heightened expression levels of cytokines and anti-angiogenic molecules in isolated CD4(+) cells from preeclampsia patients.
JOURNAL OF REPRODUCTIVE IMMUNOLOGY
(2021)
Review
Cardiac & Cardiovascular Systems
Leila Abkhooie, Mostafa M. Sarabi, Houman Kahroba, Shirin Eyvazi, Soheila Montazersaheb, Vahideh Tarhriz, Mohammad S. Hejazi
Summary: MyomiRs, known as crucial regulatory elements for cardiovascular development, are abundantly expressed in the myocardium and have been confirmed as promising diagnostic biomarkers for early diagnosis of cardiac disorders. Recent findings have focused on epigenetic modulations of MyomiRs and cardiac regeneration associated with cardiac diseases.
CURRENT CARDIOLOGY REVIEWS
(2021)
Article
Chemistry, Multidisciplinary
Rokhsareh Abedi, Jahan Bakhsh Raoof, Ayemeh Bagheri Hashkavayi, Maryam Asghari, Razieh Azimi, Mohammad Saeid Hejazi
Summary: An electrochemical DNA hybridization biosensor based on modified graphite screen-printed electrodes was developed for detection of short-sequence DNA of prostate cancer gene. The sensor demonstrated high selectivity and sensitivity in detecting the hybridization process through differential pulse voltammetric signals.
JOURNAL OF THE IRANIAN CHEMICAL SOCIETY
(2022)
Article
Pharmacology & Pharmacy
Houman Kahroba, Nasser Samadi, Mostafa Mostafazadeh, Mohamad Saied Hejazi, Mohammad Reza Sadeghi, Shahryar Hashemzadeh, Amir Taher Eftekhar Sadat, Abbas Karimi
Summary: The study identified four miRNAs in serum exosomes of gastric cancer patients that are directly associated with tumoral miRNA expression profile, with diagnostic potential. These miRNAs were significantly upregulated in exosomes and showed high correlation in expression between individuals.
Review
Virology
Soheila Montazersaheb, Seyed Mahdi Hosseiniyan Khatibi, Mohammad Saeid Hejazi, Vahideh Tarhriz, Afsaneh Farjami, Faramarz Ghasemian Sorbeni, Raheleh Farahzadi, Tohid Ghasemnejad
Summary: COVID-19 caused by SARS-CoV-2 poses a significant global health threat, leading to pneumonia and ARDS in patients. Cytokine storm, characterized by elevated levels of pro-inflammatory cytokines, including interleukins and TNF-alpha, contributes to lung damage in ARDS patients. Suppressing the inflammatory response may be a possible strategy for managing COVID-19.
Article
Biology
M. Omidi-Shahsavandi, P. Yaghmaei, S. Ahmadian, A. Ebrahim-Habibi
Summary: Silibinin and trans-chalcone were found to have inhibitory effects on insulin amyloid formation, with Silibinin showing a better effect. Animal experiments also showed that these two compounds can reduce amyloid plaque formation and improve cognitive function. Molecular docking experiments provided insights into the binding site of these compounds with insulin.
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH
(2023)
Review
Pharmacology & Pharmacy
Jeiran Pashapour-Anousheh, Abolfazl Barzegar, Mohammad Saeid Hejazi, Nikoo Hasheminejad, Hamid Reza Heidari, Elnaz Mehdizadeh Aghdam
Summary: This article reviews the mechanism and strategies for inhibiting Ras-mutated cancers. Currently, there are no approved Ras mutant inhibitors for clinical use. Research needs to focus on inhibiting specific mutants without affecting wild-type Ras variants.
PHARMACEUTICAL SCIENCES
(2022)
Article
Medicine, General & Internal
Leila Abkhooie, Mostafa Moradi Sarabi, Houman Kahroba, Hossein Ghanbarian, Soheila Montazer Saheb, Vahideh Tarhriz, Mohammad Saeid Hejazi
Summary: The study demonstrates that Cdk9 overexpression can induce DNA methylation changes in mouse myoblast cells, and this overexpression also increases the expression levels of DNMTs, further activating global and regional DNA methylation profiles.
CRESCENT JOURNAL OF MEDICAL AND BIOLOGICAL SCIENCES
(2022)
Article
Endocrinology & Metabolism
Parisa Nikasa, Bahareh Rabbani, Mohammad Saeid Hejazi, Ata Firouzi, Hossein Baharvand, Mehdi Totonchi, Nejat Mahdieh
CLINICAL PEDIATRIC ENDOCRINOLOGY
(2021)
Article
Pharmacology & Pharmacy
Vida Ebrahimi, Shirin Eyvazi, Soheila Montazersaheb, Parivar Yazdani, Mohammad Amin Hejazi, Vahideh Tarhriz, Mohammad Saeid Hejazi
Summary: Aquatic biodegrading bacteria capable of using PAHs as the sole carbon source were isolated from the Caspian lake, with 11 out of 23 bacterial isolates showing growth on supplemented media and displaying high degradation potential for phenanthrene and naphthalene. These bacteria play a critical role in the biodegradation of PAHs in the lake and contribute to the purification process of the habitat.
PHARMACEUTICAL SCIENCES
(2021)
Article
Pharmacology & Pharmacy
Faegheh Golabi, Elnaz Mehdizadeh Aghdam, Mousa Shamsi, Mohammad Hosein Sedaaghi, Abolfazl Barzegar, Mohammad Saeid Hejazi
Summary: The study applied BLBFE strategy and other feature extraction methods for the classification of riboswitch sequences, demonstrating higher accuracy, sensitivity, specificity, and f-score values in performance evaluation.
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
