Genetic mapping reveals Nfkbid as a central regulator of humoral immunity to Toxoplasma gondii

Naïve CD8 T cell IFNγ responses to a vacuolar antigen are regulated by an inflammasome-independent NLRP3 pathway and Toxoplasma gondii ROP5

(2020) Angel K. Kongsomboonvech et al.   PLoS Pathogens

TACI expression and plasma cell differentiation are impaired in the absence of functional IκBNS

(2019) Sharesta Khoenkhoen et al.   IMMUNOLOGY AND CELL BIOLOGY

B-1 cell responses to infections

(2019) Fauna L Smith et al.   CURRENT OPINION IN IMMUNOLOGY

FCRL5+ Memory B Cells Exhibit Robust Recall Responses

(2019) Charles C. Kim et al.   Cell Reports

Secreted IgM: New tricks for an old molecule

(2019) Rebecca Blandino et al.   JOURNAL OF LEUKOCYTE BIOLOGY

TLR induces reorganization of the IgM-BCR complex regulating murine B-1 cell responses to infections

(2019) Hannah P Savage et al.   eLife

B cell receptor and Toll-like receptor signaling coordinate to control distinct B-1 responses to both self and the microbiota

(2019) Lieselotte SM Kreuk et al.   eLife

The immune system utilizes two distinct effector mechanisms of T cells depending on two different life cycle stages of a single pathogen, Toxoplasma gondii, to control its cerebral infection

(2019) Yasuhiro Suzuki   PARASITOLOGY INTERNATIONAL

LAG-3 Inhibitory Receptor Expression Identifies Immunosuppressive Natural Regulatory Plasma Cells

(2018) Andreia C. Lino et al.   IMMUNITY

Clonal and atypical Toxoplasma strain differences in virulence vary with mouse sub-species

(2018) Musa A. Hassan et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Tspan8 and Tspan8/CD151 knockout mice unravel the contribution of tumor and host exosomes to tumor progression

(2018) Kun Zhao et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

IκBNS enhances follicular helper T-cell differentiation and function downstream of ASCl2

(2017) Junichi Hosokawa et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

SCIMP is a transmembrane non-TIR TLR adaptor that promotes proinflammatory cytokine production from macrophages

(2017) Lin Luo et al.   Nature Communications

Somatically Hypermutated Plasmodium-Specific IgM+ Memory B Cells Are Rapid, Plastic, Early Responders upon Malaria Rechallenge

(2016) Akshay T. Krishnamurty et al.   IMMUNITY

Local admixture of amplified and diversified secreted pathogenesis determinants shapes mosaic Toxoplasma gondii genomes

(2016) Hernan Lorenzi et al.   Nature Communications

Heterozygous Mutation in IκBNS Leads to Reduced Levels of Natural IgM Antibodies and Impaired Responses to T-Independent Type 2 Antigens

(2016) Gabriel K. Pedersen et al.   Frontiers in Immunology

Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial

(2015)   LANCET

Toxoplasma gondii Superinfection and Virulence during Secondary Infection Correlate with the Exact ROP5/ROP18 Allelic Combination

(2015) Kirk D. C. Jensen et al.   mBio

Infection-induced type I interferons activate CD11b on B-1 cells for subsequent lymph node accumulation

(2015) Elizabeth E. Waffarn et al.   Nature Communications

Transcriptional and Linkage Analyses Identify Loci that Mediate the Differential Macrophage Response to Inflammatory Stimuli and Infection

(2015) Musa A. Hassan et al.   PLoS Genetics

Cell-Mediated Immunity to Toxoplasma gondii Develops Primarily by Local Th1 Host Immune Responses in the Absence of Parasite Replication

(2014) J. P. Gigley et al.   JOURNAL OF IMMUNOLOGY

Vaccines against tropical parasitic diseases: a persisting answer to a persisting problem

(2014) David L Sacks   NATURE IMMUNOLOGY

B-1a transitional cells are phenotypically distinct and are lacking in mice deficient in IκBNS

(2014) Gabriel K. Pedersen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Atypical IκB proteins – nuclear modulators of NF-κB signaling

(2013) Marc Schuster et al.   Cell Communication and Signaling

Donor CD8+T Cells Prevent Toxoplasma gondii De-Encystation but Fail To Rescue the Exhausted Endogenous CD8+T Cell Population

(2013) Rajarshi Bhadra et al.   INFECTION AND IMMUNITY

IL-21 Is Required for Optimal Antibody Production and T Cell Responses during Chronic Toxoplasma gondii Infection

(2013) Jason S. Stumhofer et al.   PLoS One

Prematurity and Severity Are Associated With Toxoplasma gondii Alleles (NCCCTS, 1981–2009)

(2012) Rima McLeod et al.   CLINICAL INFECTIOUS DISEASES

IκBNS Protein Mediates Regulatory T Cell Development via Induction of the Foxp3 Transcription Factor

(2012) Marc Schuster et al.   IMMUNITY

Infection with Toxoplasma gondii Alters Lymphotoxin Expression Associated with Changes in Splenic Architecture

(2012) Arielle Glatman Zaretsky et al.   INFECTION AND IMMUNITY

A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity

(2012) C. N. Arnold et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antigen-specific antibody responses in B-1a and their relationship to natural immunity

(2012) Y. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impaired B Cell Development and Function in the Absence of IκBNS

(2011) Maki Touma et al.   JOURNAL OF IMMUNOLOGY

Pivotal Advance: Peritoneal cavity B-1 B cells have phagocytic and microbicidal capacities and present phagocytosed antigen to CD4+ T cells

(2011) D. Parra et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Therapeutic blockade of PD-L1 and LAG-3 rapidly clears established blood-stage Plasmodium infection

(2011) Noah S Butler et al.   NATURE IMMUNOLOGY

Control of Toxoplasma reactivation by rescue of dysfunctional CD8+ T-cell response via PD-1-PDL-1 blockade

(2011) R. Bhadra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Different B Cell Populations Mediate Early and Late Memory During an Endogenous Immune Response

(2011) K. A. Pape et al.   SCIENCE

Removal of Toxoplasma gondii Cysts from the Brain by Perforin-Mediated Activity of CD8+ T Cells

(2010) Yasuhiro Suzuki et al.   AMERICAN JOURNAL OF PATHOLOGY

Gene expression profiles of human melanoma cells with different invasive potential reveal TSPAN8 as a novel mediator of invasion

(2010) O Berthier-Vergnes et al.   BRITISH JOURNAL OF CANCER

Avirulent Uracil Auxotrophs Based on Disruption of Orotidine-5'-Monophosphate Decarboxylase Elicit Protective Immunity to Toxoplasma gondii

(2010) B. A. Fox et al.   INFECTION AND IMMUNITY

BAFF Receptor Signaling Aids the Differentiation of Immature B Cells into Transitional B Cells following Tonic BCR Signaling

(2010) S. L. Rowland et al.   JOURNAL OF IMMUNOLOGY

Dual role for B-1a cells in immunity to influenza virus infection

(2008) Youn Soo Choi et al.   JOURNAL OF EXPERIMENTAL MEDICINE