Aspirin-triggered resolvin D1 reduces parasitic cardiac load by decreasing inflammation in a murine model of early chronic Chagas disease

Resolvin D1 and E1 promote resolution of inflammation in rat cardiac fibroblast in vitro

(2021) Aimeé Salas-Hernández et al.   MOLECULAR BIOLOGY REPORTS

Role of formyl peptide receptor 2 (FPR2) in modulating immune response and heart inflammation in an experimental model of acute and chronic Chagas disease

(2021) Rafaela das Dores Pereira et al.   CELLULAR IMMUNOLOGY

Resolvin D1 Administration is Beneficial in Trypanosoma cruzi Infection

(2020) Aline L. Horta et al.   INFECTION AND IMMUNITY

Role of FAK signaling in chagasic cardiac hypertrophy

(2020) Amanda R. Tucci et al.   Brazilian Journal of Infectious Diseases

Progression of Baseline Electrocardiogram Abnormalities in Chagas Patients Undergoing Antitrypanosomal Treatment

(2019) Jonathan Soverow et al.   Open Forum Infectious Diseases

American Trypanosomiasis (Chagas Disease)

(2019) Luis E. Echeverria et al.   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

IL-10/STAT3/SOCS3 Axis Is Involved in the Anti-inflammatory Effect of Benznidazole

(2019) Ágata C. Cevey et al.   Frontiers in Immunology

Toxicity of nifurtimox as second-line treatment after benznidazole intolerance in patients with chronic Chagas disease: when available options fail

(2018) C. Crespillo-Andújar et al.   CLINICAL MICROBIOLOGY AND INFECTION

Safety Profile of Benznidazole in the Treatment of Chronic Chagas Disease: Experience of a Referral Centre and Systematic Literature Review with Meta-Analysis

(2018) Clara Crespillo-Andújar et al.   DRUG SAFETY

Resolvins in inflammation: emergence of the pro-resolving superfamily of mediators

(2018) Charles N. Serhan et al.   JOURNAL OF CLINICAL INVESTIGATION

Chagas disease

(2018) José A Pérez-Molina et al.   LANCET

Trypanosoma cruzi activates mouse cardiac fibroblasts in vitro leading to fibroblast-myofibroblast transition and increase in expression of extracellular matrix proteins

(2018) Laura Lacerda Coelho et al.   Parasites & Vectors

BALB/c and C57BL/6 Mice Cytokine Responses to Trypanosoma cruzi Infection Are Independent of Parasite Strain Infectivity

(2018) Bianca L. Ferreira et al.   Frontiers in Microbiology

Inflammatory and Pro-resolving Lipids in Trypanosomatid Infections: A Key to Understanding Parasite Control

(2018) Rodrigo A. López-Muñoz et al.   Frontiers in Microbiology

The Unsolved Jigsaw Puzzle of the Immune Response in Chagas Disease

(2018) Gonzalo R. Acevedo et al.   Frontiers in Immunology

Beneficial effects of benznidazole in Chagas disease: NIH SaMi-Trop cohort study

(2018) Clareci Silva Cardoso et al.   PLoS Neglected Tropical Diseases

Lipoxin and Resolvin Receptors Transducing the Resolution of Inflammation in Cardiovascular Disease

(2018) John Pirault et al.   Frontiers in Pharmacology

Pathology and Pathogenesis of Chagas Heart Disease

(2018) Kevin M. Bonney et al.   Annual Review of Pathology-Mechanisms of Disease

Trypanosoma cruzi : Inhibition of infection of human monocytes by aspirin

(2017) Rafael Carvalho de Freitas et al.   EXPERIMENTAL PARASITOLOGY

Profiles of cardiovascular biomarkers according to severity stages of Chagas cardiomyopathy

(2017) Luis E. Echeverría et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Resolvin D1 Improves the Resolution of Inflammation via Activating NF-κB p50/p50–Mediated Cyclooxygenase-2 Expression in Acute Respiratory Distress Syndrome

(2017) Ye Gao et al.   JOURNAL OF IMMUNOLOGY

Chronic Chagas cardiomyopathy: a review of the main pathogenic mechanisms and the efficacy of aetiological treatment following the BENznidazole Evaluation for Interrupting Trypanosomiasis (BENEFIT) trial

(2017) Anis Rassi Jr et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Discovery of specialized pro-resolving mediators marks the dawn of resolution physiology and pharmacology

(2017) Charles N. Serhan   MOLECULAR ASPECTS OF MEDICINE

Efferocytosis of Pathogen-Infected Cells

(2017) Niloofar Karaji et al.   Frontiers in Immunology

Effects of aspirin-triggered resolvin D1 on peripheral blood mononuclear cells from patients with Chagas' heart disease

(2016) Haline Ogata et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Resolvin D1, resolvin D2 and maresin 1 activate the GSK3β anti-inflammatory axis in TLR4-engaged human monocytes

(2016) Zhen Gu et al.   Innate Immunity

Low-dose benznidazole treatment results in parasite clearance and attenuates heart inflammatory reaction in an experimental model of infection with a highly virulent Trypanosoma cruzi strain

(2016) Ágata Carolina Cevey et al.   International Journal for Parasitology-Drugs and Drug Resistance

LXA4 actions direct fibroblast function and wound closure

(2015) Bruno S. Herrera et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Resolvin D1 activates the inflammation resolving response at splenic and ventricular site following myocardial infarction leading to improved ventricular function

(2015) Vasundhara Kain et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Randomized Trial of Benznidazole for Chronic Chagas’ Cardiomyopathy

(2015) Carlos A. Morillo et al.   NEW ENGLAND JOURNAL OF MEDICINE

Interleukin-10 and tumour necrosis factor-alpha serum levels in chronic Chagas disease patients

(2015) R. H. T. Vasconcelos et al.   PARASITE IMMUNOLOGY

Immunity and immune modulation inTrypanosoma cruziinfection

(2015) Fabíola Cardillo et al.   Pathogens and Disease

Inhibition of Cyclooxygenase-1 and Cyclooxygenase-2 Impairs Trypanosoma cruzi Entry into Cardiac Cells and Promotes Differential Modulation of the Inflammatory Response

(2014) Aparecida D. Malvezi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Acute Phase ofTrypanosoma cruziInfection Is Attenuated in 5-Lipoxygenase-Deficient Mice

(2014) Adriana M. C. Canavaci et al.   MEDIATORS OF INFLAMMATION

Pro-resolving lipid mediators are leads for resolution physiology

(2014) Charles N. Serhan   NATURE

Immunoregulatory networks in human Chagas disease

(2014) W. O. Dutra et al.   PARASITE IMMUNOLOGY

Plasma Cytokine Expression Is Associated with Cardiac Morbidity in Chagas Disease

(2014) Giovane Rodrigo Sousa et al.   PLoS One

Resolvin D1 limits 5-lipoxygenase nuclear localization and leukotriene B4synthesis by inhibiting a calcium-activated kinase pathway

(2014) Gabrielle Fredman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aspirin-triggered resolvin D1 down-regulates inflammatory responses and protects against endotoxin-induced acute kidney injury

(2014) Jiao Chen et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

15-Epi-lipoxin A4 inhibits human neutrophil superoxide anion generation by regulating polyisoprenyl diphosphate phosphatase 1

(2013) Troy Carlo et al.   FASEB JOURNAL

Protection of vascular endothelium by aspirin in a murine model of chronic Chagas’ disease

(2013) Alfredo Molina-Berríos et al.   PARASITOLOGY RESEARCH

Trypanosoma cruzi Infection and Endothelin-1 Cooperatively Activate Pathogenic Inflammatory Pathways in Cardiomyocytes

(2013) Ricardo S. Corral et al.   PLoS Neglected Tropical Diseases

Protective Role of Acetylsalicylic Acid in Experimental Trypanosoma cruzi Infection: Evidence of a 15-epi-Lipoxin A4-Mediated Effect

(2013) Alfredo Molina-Berríos et al.   PLoS Neglected Tropical Diseases

Role of SOCS2 in Modulating Heart Damage and Function in a Murine Model of Acute Chagas Disease

(2012) Lisia Esper et al.   AMERICAN JOURNAL OF PATHOLOGY

Interleukin-10 Inhibits Lipopolysaccharide-induced Tumor Necrosis Factor-α Translation through a SHIP1-dependent Pathway

(2012) Catherine S. Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of Benznidazole by Trypanosomal Type I Nitroreductases Results in Glyoxal Formation

(2011) Belinda S. Hall et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IL-10 Limits Parasite Burden and Protects against Fatal Myocarditis in a Mouse Model of Trypanosoma cruzi Infection

(2011) E. Roffe et al.   JOURNAL OF IMMUNOLOGY

Omega-3 Fatty Acid-Derived Mediators 17(R)-Hydroxy Docosahexaenoic Acid, Aspirin-Triggered Resolvin D1 and Resolvin D2 Prevent Experimental Colitis in Mice

(2011) A. F. Bento et al.   JOURNAL OF IMMUNOLOGY

ECG Detection of Murine Chagasic Cardiomyopathy

(2010) Christopher S. Eickhoff et al.   JOURNAL OF PARASITOLOGY

5-Lipoxygenase is a key determinant of acute myocardial inflammation and mortality during Trypanosoma cruzi infection

(2010) Wander R. Pavanelli et al.   MICROBES AND INFECTION

In vivo infection by Trypanosoma cruzi: The conserved FLY domain of the gp85/trans-sialidase family potentiates host infection

(2010) R. R. TONELLI et al.   PARASITOLOGY

Antioxidant therapy attenuates oxidative insult caused by benzonidazole in chronic Chagas' heart disease

(2009) Carine Muniz Ribeiro et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY