Identification of the potential active site of the septal peptidoglycan polymerase FtsW

Class A PBPs: it is time to rethink traditional paradigms

(2021) Daniel Straume et al.   MOLECULAR MICROBIOLOGY

Regulation and function of class A Penicillin-binding proteins

(2021) Manuel Pazos et al.   CURRENT OPINION IN MICROBIOLOGY

Class A Penicillin-Binding Protein-Mediated Cell Wall Synthesis Promotes Structural Integrity during Peptidoglycan Endopeptidase Insufficiency in Vibrio cholerae

(2021) Shannon G. Murphy et al.   mBio

Genetic analysis of the septal peptidoglycan synthase FtsWI complex supports a conserved activation mechanism for SEDS-bPBP complexes

(2021) Ying Li et al.   PLoS Genetics

Highly accurate protein structure prediction with AlphaFold

(2021) John Jumper et al.   NATURE

Discovery of a Diverse Set of Bacteria That Build Their Cell Walls without the Canonical Peptidoglycan Polymerase aPBP

(2021) Sharanjeet Atwal et al.   mBio

Regulation of peptidoglycan synthesis and remodelling

(2020) Alexander J. F. Egan et al.   NATURE REVIEWS MICROBIOLOGY

Fluorescence anisotropy assays for high throughput screening of compounds binding to lipid II, PBP1b, FtsW and MurJ

(2020) Adrien Boes et al.   Scientific Reports

Structural coordination of polymerization and crosslinking by a SEDS–bPBP peptidoglycan synthase complex

(2020) Megan Sjodt et al.   Nature Microbiology

A conserved subcomplex within the bacterial cytokinetic ring activates cell wall synthesis by the FtsW-FtsI synthase

(2020) Lindsey S. Marmont et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MreC and MreD balance the interaction between the elongasome proteins PBP2 and RodA

(2020) Xiaolong Liu et al.   PLoS Genetics

FtsW is a peptidoglycan polymerase that is functional only in complex with its cognate penicillin-binding protein

(2019) Atsushi Taguchi et al.   Nature Microbiology

Peptidoglycan Remodeling Enables Escherichia coli To Survive Severe Outer Membrane Assembly Defect

(2019) Niccolò Morè et al.   mBio

Direction of Chain Growth and Substrate Preferences of Shape, Elongation, Division, and Sporulation-Family Peptidoglycan Glycosyltransferases

(2019) Michael A. Welsh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanisms of Incorporation for D-Amino Acid Probes That Target Peptidoglycan Biosynthesis

(2019) Erkin Kuru et al.   ACS Chemical Biology

Structure of the peptidoglycan polymerase RodA resolved by evolutionary coupling analysis

(2018) Megan Sjodt et al.   NATURE

A central role for PBP2 in the activation of peptidoglycan polymerization by the bacterial cell elongation machinery

(2018) Patricia D. A. Rohs et al.   PLoS Genetics

Peptidoglycan in obligate intracellular bacteria

(2017) Christian Otten et al.   MOLECULAR MICROBIOLOGY

GTPase activity–coupled treadmilling of the bacterial tubulin FtsZ organizes septal cell wall synthesis

(2017) Xinxing Yang et al.   SCIENCE

Treadmilling by FtsZ filaments drives peptidoglycan synthesis and bacterial cell division

(2017) Alexandre W. Bisson-Filho et al.   SCIENCE

Molecular architecture of the PBP2–MreC core bacterial cell wall synthesis complex

(2017) Carlos Contreras-Martel et al.   Nature Communications

RodA as the missing glycosyltransferase in Bacillus subtilis and antibiotic discovery for the peptidoglycan polymerase pathway

(2017) Kaveh Emami et al.   Nature Microbiology

Interplay between Penicillin-binding proteins and SEDS proteins promotes bacterial cell wall synthesis

(2017) Sophie Leclercq et al.   Scientific Reports

SEDS proteins are a widespread family of bacterial cell wall polymerases

(2016) Alexander J. Meeske et al.   NATURE

FtsEX acts on FtsA to regulate divisome assembly and activity

(2016) Shishen Du et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial cell wall biogenesis is mediated by SEDS and PBP polymerase families functioning semi-autonomously

(2016) Hongbaek Cho et al.   Nature Microbiology

A role for the FtsQLB complex in cytokinetic ring activation revealed by anftsLallele that accelerates division

(2015) Mary-Jane Tsang et al.   MOLECULAR MICROBIOLOGY

Roles for both FtsA and the FtsBLQ subcomplex in FtsN-stimulated cell constriction inEscherichia coli

(2015) Bing Liu et al.   MOLECULAR MICROBIOLOGY

Specificity of the Transport of Lipid II by FtsW inEscherichia coli

(2014) Tamimount Mohammadi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A DNA Damage-Induced, SOS-Independent Checkpoint Regulates Cell Division in Caulobacter crescentus

(2014) Joshua W. Modell et al.   PLOS BIOLOGY

In Situ Probing of Newly Synthesized Peptidoglycan in Live Bacteria with FluorescentD-Amino Acids

(2012) Erkin Kuru et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Identification of FtsW as a transporter of lipid-linked cell wall precursors across the membrane

(2011) Tamimount Mohammadi et al.   EMBO JOURNAL

A Fail-Safe Mechanism in the Septal Ring Assembly Pathway Generated by the Sequential Recruitment of Cell Separation Amidases and Their Activators

(2011) N. T. Peters et al.   JOURNAL OF BACTERIOLOGY

From the regulation of peptidoglycan synthesis to bacterial growth and morphology

(2011) Athanasios Typas et al.   NATURE REVIEWS MICROBIOLOGY

Processive Movement of MreB-Associated Cell Wall Biosynthetic Complexes in Bacteria

(2011) J. Dominguez-Escobar et al.   SCIENCE

Coupled, Circumferential Motions of the Cell Wall Synthesis Machinery and MreB Filaments in B. subtilis

(2011) E. C. Garner et al.   SCIENCE

Self-Enhanced Accumulation of FtsN at Division Sites and Roles for Other Proteins with a SPOR Domain (DamX, DedD, and RlpA) in Escherichia coli Cell Constriction

(2009) M. A. Gerding et al.   JOURNAL OF BACTERIOLOGY

FtsN--Trigger for Septation

(2009) J. Lutkenhaus   JOURNAL OF BACTERIOLOGY