A hybrid stochastic-deterministic approach to explore multiple infection and evolution in HIV

Effect of synaptic cell-to-cell transmission and recombination on the evolution of double mutants in HIV

(2020) Jesse Kreger et al.   Journal of the Royal Society Interface

Mutant Evolution in Spatially Structured and Fragmented Expanding Populations

(2020) Dominik Wodarz et al.   GENETICS

The role of telomere shortening in carcinogenesis: A hybrid stochastic-deterministic approach

(2018) Ignacio A. Rodriguez-Brenes et al.   JOURNAL OF THEORETICAL BIOLOGY

Defining total-body AIDS-virus burden with implications for curative strategies

(2017) Jacob D Estes et al.   NATURE MEDICINE

Excess of mutational jackpot events in expanding populations revealed by spatial Luria–Delbrück experiments

(2016) Diana Fusco et al.   Nature Communications

In Vivo HIV-1 Cell-to-Cell Transmission Promotes Multicopy Micro-compartmentalized Infection

(2016) Kenneth M. Law et al.   Cell Reports

New virus dynamics in the presence of multiple infection

(2015) Ani Asatryan et al.   JOURNAL OF THEORETICAL BIOLOGY

HIV cell-to-cell transmission: effects on pathogenesis and antiretroviral therapy

(2015) Luis M. Agosto et al.   TRENDS IN MICROBIOLOGY

Virus dynamics in the presence of synaptic transmission

(2013) Natalia L. Komarova et al.   MATHEMATICAL BIOSCIENCES

Relations between deterministic and stochastic thresholds for disease extinction in continuous- and discrete-time infectious disease models

(2013) L.J.S. Allen et al.   MATHEMATICAL BIOSCIENCES

Multiple proviral integration events after virological synapse-mediated HIV-1 spread

(2013) Rebecca A. Russell et al.   VIROLOGY

Synaptic transmission and the susceptibility of HIV infection to anti-viral drugs

(2013) Natalia L. Komarova et al.   Scientific Reports

Single Cell Analysis of Lymph Node Tissue from HIV-1 Infected Patients Reveals that the Majority of CD4+ T-cells Contain One HIV-1 DNA Molecule

(2013) Lina Josefsson et al.   PLoS Pathogens

Effect of Synaptic Transmission on Viral Fitness in HIV Infection

(2012) Natalia L. Komarova et al.   PLoS One

Multiscale analysis of slow-fast neuronal learning models with noise

(2012) Mathieu Galtier et al.   Journal of Mathematical Neuroscience

Multiscale Cancer Modeling

(2011) Thomas S. Deisboeck et al.   Annual Review of Biomedical Engineering

Cell-to-cell spread of HIV permits ongoing replication despite antiretroviral therapy

(2011) Alex Sigal et al.   NATURE

Majority of CD4+ T cells from peripheral blood of HIV-1-infected individuals contain only one HIV DNA molecule

(2011) L. Josefsson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Estimation of the Initial Viral Growth Rate and Basic Reproductive Number during Acute HIV-1 Infection

(2010) R. M. Ribeiro et al.   JOURNAL OF VIROLOGY

Biochemical simulations: stochastic, approximate stochastic and hybrid approaches

(2009) J. Pahle   BRIEFINGS IN BIOINFORMATICS

Tyrosine kinase inhibitor therapy can cure chronic myeloid leukemia without hitting leukemic stem cells

(2009) T. Lenaerts et al.   HAEMATOLOGICA

Quantitative 3D Video Microscopy of HIV Transfer Across T Cell Virological Synapses

(2009) W. Hubner et al.   SCIENCE

Slow-scale tau-leaping method

(2008) Yang Cao et al.   COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING

Avoiding the void: cell-to-cell spread of human viruses

(2008) Quentin Sattentau   NATURE REVIEWS MICROBIOLOGY

Viral complementation allows HIV-1 replication without integration

(2008) Huub C Gelderblom et al.   Retrovirology