A literature review of severity scores for adults with influenza or community-acquired pneumonia – implications for influenza vaccines and therapeutics

Does influenza vaccination attenuate the severity of breakthrough infections? A narrative review and recommendations for further research

(2021) Jill M. Ferdinands et al.   VACCINE

Frailty Hinders Recovery From Influenza and Acute Respiratory Illness in Older Adults

(2020) Caitlin Lees et al.   JOURNAL OF INFECTIOUS DISEASES

The role of Endocan as a Prognostic Biomarker in community-acquired pneumonia

(2019) Şenay Günaydın et al.   Pakistan Journal of Medical Sciences

Efficacy and accuracy of qSOFA and SOFA scores as prognostic tools for community-acquired and healthcare-associated pneumonia

(2019) Nobuhiro Asai et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Lymphopenic community-acquired pneumonia is associated with a dysregulated immune response and increased severity and mortality

(2019) Raúl Méndez et al.   JOURNAL OF INFECTION

Predicting the need for ICU admission in community-acquired pneumonia

(2019) Alessandra Morello Gearhart et al.   RESPIRATORY MEDICINE

Predictors of mortality of influenza virus infections in a Swiss Hospital during four influenza seasons: Role of quick sequential organ failure assessment

(2019) Matthaios Papadimitriou-Olivgeris et al.   European Journal of Internal Medicine

The risk stratification and prognostic prediction value of procalcitonin and clinical severity scores on patients with community-acquired pneumonia in emergency department

(2018) Haijiang Zhou et al.   AMERICAN JOURNAL OF EMERGENCY MEDICINE

Comprehensive analysis of prognostic factors in hospitalized patients with pneumonia occurring outside hospital: Serum albumin is not less important than pneumonia severity assessment scale

(2018) Hiroyuki Miyazaki et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

High Level of Neutrophil Extracellular Traps Correlates With Poor Prognosis of Severe Influenza A Infection

(2018) Liuluan Zhu et al.   JOURNAL OF INFECTIOUS DISEASES

Estimates of global seasonal influenza-associated respiratory mortality: a modelling study

(2018) A Danielle Iuliano et al.   LANCET

Prognostic factors for mortality due to pneumonia among adults from different age groups in Singapore and mortality predictions based on PSI and CURB-65

(2018) ZX Zhang et al.   SINGAPORE MEDICAL JOURNAL

Six underlying health conditions strongly influence mortality based on pneumonia severity in an ageing population of Japan: a prospective cohort study

(2018) Sugihiro Hamaguchi et al.   BMC Pulmonary Medicine

Influenza vaccine effectiveness in preventing influenza-associated intensive care admissions and attenuating severe disease among adults in New Zealand 2012–2015

(2018) Mark G. Thompson et al.   VACCINE

Expanded A-DROP Score: A New Scoring System for the Prediction of Mortality in Hospitalized Patients with Community-acquired Pneumonia

(2018) June Hong Ahn et al.   Scientific Reports

Validity of SMART-COP score in prognosis and severity of community acquired pneumonia in the emergency department

(2018) Babak Ehsanpoor et al.   AMERICAN JOURNAL OF EMERGENCY MEDICINE

Cytokine responses, microbial aetiology and short-term outcome in community-acquired pneumonia

(2017) William W. Siljan et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

A new method to predict hospital mortality in severe community acquired pneumonia

(2017) Xin Wang et al.   European Journal of Internal Medicine

Circulating level of high mobility group box-1 predicts the severity of community-acquired pneumonia: Regulation of inflammatory responses via the c-Jun N-terminal signaling pathway in macrophages

(2017) Hsiang-Ling Wang et al.   Molecular Medicine Reports

Mortality prediction using serum biomarkers and various clinical risk scales in community-acquired pneumonia

(2017) Min Woo Kim et al.   SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION

Prognostic factors in hospitalized community-acquired pneumonia: a retrospective study of a prospective observational cohort

(2017) Akihiro Ito et al.   BMC Pulmonary Medicine

Validation of modified early warning score using serum lactate level in community-acquired pneumonia patients. The National Early Warning Score–Lactate score

(2016) Sion Jo et al.   AMERICAN JOURNAL OF EMERGENCY MEDICINE

Usefulness of plasma neutrophil gelatinase-associated lipocalin concentration for predicting the severity and mortality of patients with community-acquired pneumonia

(2016) Jong Won Kim et al.   CLINICA CHIMICA ACTA

CRP/IL-6/IL-10 Single-Nucleotide Polymorphisms Correlate with the Susceptibility and Severity of Community-Acquired Pneumonia

(2016) Shou-Chu Chou et al.   Genetic Testing and Molecular Biomarkers

Multimarker Prognostication for Hospitalized Patients with Community-acquired Pneumonia

(2016) So Yeon Lee et al.   INTERNAL MEDICINE

Assessment of Clinical Criteria for Sepsis

(2016) Christopher W. Seymour et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Benefit of Early Initiation of Influenza Antiviral Treatment to Pregnant Women Hospitalized With Laboratory-Confirmed Influenza

(2016) Ikwo K. Oboho et al.   JOURNAL OF INFECTIOUS DISEASES

Variable influenza vaccine effectiveness by subtype: a systematic review and meta-analysis of test-negative design studies

(2016) Edward A Belongia et al.   LANCET INFECTIOUS DISEASES

YKL-40, CCL18 and SP-D predict mortality in patients hospitalized with community-acquired pneumonia

(2016) Simone M.C. Spoorenberg et al.   RESPIROLOGY

Influenza vaccine effectiveness by test-negative design – Comparison of inpatient and outpatient settings

(2016) Shuo Feng et al.   VACCINE

Expanded CURB-65: a new score system predicts severity of community-acquired pneumonia with superior efficiency

(2016) Jin-liang Liu et al.   Scientific Reports

Failure of CRP decline within three days of hospitalization is associated with poor prognosis of Community-acquired Pneumonia

(2016) Stine Bang Andersen et al.   Infectious Diseases

Combination of mean platelet volume and the CURB-65 score better predicts 28-day mortality in patients with community-acquired pneumonia

(2015) Yalcin Golcuk et al.   AMERICAN JOURNAL OF EMERGENCY MEDICINE

Initial serum lactate level is associated with inpatient mortality in patients with community-acquired pneumonia

(2015) Min Hyuk Gwak et al.   AMERICAN JOURNAL OF EMERGENCY MEDICINE

CUR-65 Score for Community-Acquired Pneumonia Predicted Mortality Better Than CURB-65 Score in Low–Mortality Rate Settings

(2015) Hai-yan Li et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Impact of Prompt Influenza Antiviral Treatment on Extended Care Needs After Influenza Hospitalization Among Community-Dwelling Older Adults

(2015) Sandra S. Chaves et al.   CLINICAL INFECTIOUS DISEASES

Desirability of Outcome Ranking (DOOR) and Response Adjusted for Duration of Antibiotic Risk (RADAR)

(2015) Scott R. Evans et al.   CLINICAL INFECTIOUS DISEASES

Performance of pro-adrenomedullin for identifying adverse outcomes in community-acquired pneumonia

(2015) Pedro P. España et al.   JOURNAL OF INFECTION

Does Influenza Vaccination Modify Influenza Severity? Data on Older Adults Hospitalized With Influenza During the 2012−2013 Season in the United States

(2015) Carmen S. Arriola et al.   JOURNAL OF INFECTIOUS DISEASES

Clinical risk scores and blood biomarkers as predictors of long-term outcome in patients with community-acquired pneumonia: a 6-year prospective follow-up study

(2015) M. Alan et al.   JOURNAL OF INTERNAL MEDICINE

Modified IDSA/ATS Minor Criteria for Severe Community-Acquired Pneumonia Best Predicted Mortality

(2015) Hai-yan Li et al.   MEDICINE

Usefulness of Midregional Proadrenomedullin to Predict Poor Outcome in Patients with Community Acquired Pneumonia

(2015) Susana Gordo-Remartínez et al.   PLoS One

In-hospital mortality risk factors in community acquired pneumonia: evaluation of immunocompetent adult patients without comorbidities

(2015) Miguel Hernan Vicco et al.   Revista da Associacao Medica Brasileira

Interleukin-6 and procalcitonin as biomarkers in mortality prediction of hospitalized patients with community acquired pneumonia

(2014) Bojan Zaric et al.   Annals of Thoracic Medicine

Lysophosphatidylcholine as a prognostic marker in community-acquired pneumonia requiring hospitalization: a pilot study

(2014) W. H. Cho et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Soluble Thrombomodulin to Evaluate the Severity and Outcome of Community-Acquired Pneumonia

(2014) Qin Yin et al.   INFLAMMATION

Plasma levels of soluble Axl correlate with severity of community-acquired pneumonia

(2014) CHUNG-PO KO et al.   Molecular Medicine Reports

Role of Presepsin (sCD14-ST) and the CURB65 scoring system in predicting severity and outcome of community-acquired pneumonia in an emergency department

(2014) Bo Liu et al.   RESPIRATORY MEDICINE

Oseltamivir for influenza in adults and children: systematic review of clinical study reports and summary of regulatory comments

(2014) T. Jefferson et al.   BMJ-British Medical Journal

Effectiveness of neuraminidase inhibitors in reducing mortality in patients admitted to hospital with influenza A H1N1pdm09 virus infection: a meta-analysis of individual participant data

(2014) Stella G Muthuri et al.   Lancet Respiratory Medicine

The circulating level of MMP-9 and its ratio to TIMP-1 as a predictor of severity in patients with community-acquired pneumonia

(2013) Ting-Yen Chiang et al.   CLINICA CHIMICA ACTA

The Simple Clinical Score: a tool for benchmarking of emergency admissions in acute internal medicine

(2013) C. Subbe et al.   CLINICAL MEDICINE

NEWSDIG: The National Early Warning Score Development and Implementation Group

(2013) M. Jones   CLINICAL MEDICINE

Influenza pneumonia among adolescents and adults: a concurrent comparison between influenza A (H1N1) pdm09 and A (H3N2) in the post-pandemic period

(2013) Shu Qiao Yang et al.   Clinical Respiratory Journal

CURB-65 as an initial prognostic score in Internal Medicine patients

(2013) Carlos Armiñanzas et al.   European Journal of Internal Medicine

Usefulness of Plasma YKL-40 in Management of Community-Acquired Pneumonia Severity in Patients

(2013) Hsiang-Ling Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

IgM levels in plasma predict outcome in severe pandemic influenza

(2013) Mar Justel et al.   JOURNAL OF CLINICAL VIROLOGY

Comparison of Severe Healthcare-Associated Pneumonia with Severe Community-Acquired Pneumonia

(2013) Byeong-Ho Jeong et al.   LUNG

Proadrenomedullin, a useful tool for risk stratification in high Pneumonia Severity Index score community acquired pneumonia

(2012) Caroline Courtais et al.   AMERICAN JOURNAL OF EMERGENCY MEDICINE

Proadrenomedullin Improves Risk of Early Admission to ICU Score for Predicting Early Severe Community-Acquired Pneumonia

(2012) Bertrand Renaud et al.   CHEST

Addition of Vitamin D Status to Prognostic Scores Improves the Prediction of Outcome in Community-Acquired Pneumonia

(2012) Hilde H. F. Remmelts et al.   CLINICAL INFECTIOUS DISEASES

Influenza-Associated Pneumonia Among Hospitalized Patients With 2009 Pandemic Influenza A (H1N1) Virus--United States, 2009

(2012) S. Jain et al.   CLINICAL INFECTIOUS DISEASES

CURB-65 score predicted mortality in community-acquired pneumonia better than IDSA/ATS minor criteria in a low-mortality-rate setting

(2012) Q. Guo et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Utility of two biomarkers for directing care among patients with non-severe community-acquired pneumonia

(2012) P. P. España et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

A Functional Variation in CD55 Increases the Severity of 2009 Pandemic H1N1 Influenza A Virus Infection

(2012) Jie Zhou et al.   JOURNAL OF INFECTIOUS DISEASES

Fulfilling the promise of rotavirus vaccines: how far have we come since licensure?

(2012) Manish M Patel et al.   LANCET INFECTIOUS DISEASES

The Neutrophil-Lymphocyte Count Ratio in Patients with Community-Acquired Pneumonia

(2012) Cornelis P. C. de Jager et al.   PLoS One

Chest radiological findings of influenza A H1N1 pneumonia

(2012) A. Nicolini et al.   Revista Portuguesa de Pneumologia

The SMART-COP score performs well for pneumonia risk stratification in Australia’s Tropical Northern Territory: a prospective cohort study

(2012) Karen L. Robins-Browne et al.   TROPICAL MEDICINE & INTERNATIONAL HEALTH

Direct Comparison of Three Natriuretic Peptides for Prediction of Short- and Long-term Mortality in Patients With Community-Acquired Pneumonia

(2011) Albina Nowak et al.   CHEST

Severity assessment tools in ICU patients with 2009 Influenza A (H1N1) pneumonia

(2011) J.M. Pereira et al.   CLINICAL MICROBIOLOGY AND INFECTION

Prognostic power of proadrenomedullin in community-acquired pneumonia is independent of aetiology

(2011) Salvador Bello et al.   EUROPEAN RESPIRATORY JOURNAL

Validation of Scoring Systems for Predicting Severe Community-Acquired Pneumonia

(2011) Hajime Fukuyama et al.   INTERNAL MEDICINE

The impact of coagulation parameters on the outcomes of patients with severe community-acquired pneumonia requiring intensive care unit admission

(2011) Jorge I.F. Salluh et al.   JOURNAL OF CRITICAL CARE

CURB-65 and SMRT-CO in the prediction of early transfers to the intensive care unit among patients with community-acquired pneumonia initially admitted to a general ward

(2011) Moises A. Huaman et al.   Journal of Hospital Medicine

A Prediction Rule to Identify Severe Cases among Adult Patients Hospitalized with Pandemic Influenza A (H1N1) 2009

(2011) Won Sup Oh et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

Low CURB-65 is of limited value in deciding discharge of patients with community-acquired pneumonia

(2011) Stefano Aliberti et al.   RESPIRATORY MEDICINE

Usefulness of a semi-quantitative procalcitonin test and the A-DROP Japanese prognostic scale for predicting mortality among adults hospitalized with community-acquired pneumonia

(2011) YU KASAMATSU et al.   RESPIROLOGY

CURB-65, PSI, and APACHE II to Assess Mortality Risk in Patients With Severe Sepsis and Community Acquired Pneumonia in PROWESS

(2011) Guy Richards et al.   JOURNAL OF INTENSIVE CARE MEDICINE

Influenza A 2009 (H1N1) Virus in Admitted and Critically Ill Patients

(2011) Andrew C. Miller et al.   JOURNAL OF INTENSIVE CARE MEDICINE

C-reactive protein serum levels as an early predictor of outcome in patients with pandemic H1N1 influenza A virus infection

(2010) Ofer Zimmerman et al.   BMC INFECTIOUS DISEASES

Predicting mortality in patients with community-acquired pneumonia and low CURB-65 scores

(2010) D. Ronan et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Adrenal function is related to prognosis in moderate community-acquired pneumonia

(2010) M. Kolditz et al.   EUROPEAN RESPIRATORY JOURNAL

Albumin and C-reactive protein have prognostic significance in patients with community-acquired pneumonia

(2010) Jae Hyuk Lee et al.   JOURNAL OF CRITICAL CARE

Functional status determined by Barthel Index predicts community acquired pneumonia mortality in general population

(2010) José Murcia et al.   JOURNAL OF INFECTION

Coagulation and inflammation biomarkers may help predict the severity of community-acquired pneumonia

(2010) Dimitrios I. AGAPAKIS et al.   RESPIROLOGY

Comparison of clinical characteristics and performance of pneumonia severity score and CURB-65 among younger adults, elderly and very old subjects

(2010) J.-H. Chen et al.   THORAX

Outcomes of adults hospitalised with severe influenza

(2010) N. Lee et al.   THORAX

Midregional Proadrenomedullin as a Prognostic Tool in Community-Acquired Pneumonia

(2009) David T. Huang et al.   CHEST

Severe Community‐Acquired Pneumonia: Validation of the Infectious Diseases Society of America/American Thoracic Society Guidelines to Predict an Intensive Care Unit Admission

(2009) Adamantia Liapikou et al.   CLINICAL INFECTIOUS DISEASES

Evaluation of the performance of CURB-65 with increasing age

(2009) M. Parsonage et al.   CLINICAL MICROBIOLOGY AND INFECTION

Plasma Transforming Growth Factor-β1 Level in Patients with Severe Community-acquired Pneumonia and Association with Disease Severity

(2009) Huang-Pin Wu et al.   JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION

Validation and clinical implications of the IDSA/ATS minor criteria for severe community-acquired pneumonia

(2009) J Phua et al.   THORAX

Biomarkers improve mortality prediction by prognostic scales in community-acquired pneumonia

(2009) R Menendez et al.   THORAX

Risk Prediction With Procalcitonin and Clinical Rules in Community-Acquired Pneumonia

(2008) David T. Huang et al.   ANNALS OF EMERGENCY MEDICINE

Endothelin-1 precursor peptides correlate with severity of disease and outcome in patients with community acquired pneumonia

(2008) Philipp Schuetz et al.   BMC INFECTIOUS DISEASES

SMART‐COP: A Tool for Predicting the Need for Intensive Respiratory or Vasopressor Support in Community‐Acquired Pneumonia

(2008) Patrick G. P. Charles et al.   CLINICAL INFECTIOUS DISEASES

Predicting the Need for Mechanical Ventilation and/or Inotropic Support for Young Adults Admitted to the Hospital with Community‐Acquired Pneumonia

(2008) James D. Chalmers et al.   CLINICAL INFECTIOUS DISEASES

Predicting mortality with pneumonia severity scores: importance of model recalibration to local settings

(2008) P. SCHUETZ et al.   EPIDEMIOLOGY AND INFECTION

Use of B-type natriuretic peptide in the risk stratification of community-acquired pneumonia

(2008) M. Christ-Crain et al.   JOURNAL OF INTERNAL MEDICINE

Comparison of severity scoring systems A-DROP and CURB-65 for community-acquired pneumonia

(2008) Yuichiro SHINDO et al.   RESPIROLOGY

Incidence and characteristics of viral community-acquired pneumonia in adults

(2007) L C Jennings et al.   THORAX