Article
Endocrinology & Metabolism
Emily A. Wolverton, Marty Kwok-Shing Wong, Perry E. Davis, Brianne Hoglin, Ingo Braasch, Robert M. Dores
GENERAL AND COMPARATIVE ENDOCRINOLOGY
(2019)
Article
Ecology
Murielle Alund, Nathan Emery, Benjamin J. M. Jarrett, Kirsty J. MacLeod, Helen F. McCreery, Nadya Mamoozadeh, John G. Phillips, Jory Schossau, Andrew W. Thompson, Alexa R. Warwick, Kelsey M. Yule, Erin R. Zylstra, Eben Gering
NATURE ECOLOGY & EVOLUTION
(2020)
Article
Ecology
Kang Du, Matthias Stoeck, Susanne Kneitz, Christophe Klopp, Joost M. Woltering, Mateus Contar Adolfi, Romain Feron, Dmitry Prokopov, Alexey Makunin, Ilya Kichigin, Cornelia Schmidt, Petra Fischer, Heiner Kuhl, Sven Wuertz, Joern Gessner, Werner Kloas, Cedric Cabau, Carole Iampietro, Hugues Parrinello, Chad Tomlinson, Laurent Journot, John H. Postlethwait, Ingo Braasch, Vladimir Trifonov, Wesley C. Warren, Axel Meyer, Yann Guiguen, Manfred Schartl
NATURE ECOLOGY & EVOLUTION
(2020)
Editorial Material
Biochemistry & Molecular Biology
Ingo Braasch
Article
Multidisciplinary Sciences
Robin J. Vigouroux, Karine Duroure, Juliette Vougny, Shahad Albadri, Peter Kozulin, Eloisa Herrera, Kim Nguyen-Ba-Charvet, Ingo Braasch, Rodrigo Suarez, Filippo Del Bene, Alain Chedotal
Summary: The study reveals that bilateral visual projections exist in non-teleost fishes, and that the developmental program specifying visual system laterality differs between fishes and mammals. The presence of ipsilateral projections in fish ganglion cells appears to be absent due to the lack of the Zic2 transcription factor.
Article
Genetics & Heredity
Alex Dornburg, Dustin J. Wcisel, Katerina Zapfe, Emma Ferraro, Lindsay Roupe-Abrams, Andrew W. Thompson, Ingo Braasch, Tatsuya Ota, Jeffrey A. Yoder
Summary: The study investigates the receptor diversity of two innate immune gene families in the teleost sister lineage, Holostei, providing insights into the evolutionary history and linkage of these gene clusters. The findings reveal a diversity in these immune receptors in Holostei that rivals that of many teleosts, challenging prevailing expectations regarding the consequences of genome duplication during actinopterygian evolution.
Article
Genetics & Heredity
Andrew W. Thompson, M. Brent Hawkins, Elise Parey, Dustin J. Wcisel, Tatsuya Ota, Kazuhiko Kawasaki, Emily Funk, Mauricio Losilla, Olivia E. Fitch, Qiaowei Pan, Romain Feron, Alexandra Louis, Jerome Montfort, Marine Milhes, Brett L. Racicot, Kevin L. Childs, Quenton Fontenot, Allyse Ferrara, Solomon R. David, Amy R. McCune, Alex Dornburg, Jeffrey A. Yoder, Yann Guiguen, Hugues Roest Crollius, Camille Berthelot, Matthew P. Harris, Ingo Braasch
Summary: The analysis of a chromosome-level bowfin genome assembly sheds light on the evolution of neopterygian fishes. Through examining chromatin accessibility and gene expression profiling, insights into bowfin embryonic development have been provided. The resources obtained from this study connect developmental evolution among bony fishes, emphasizing the importance of bowfin in illustrating vertebrate biology and diversity in the genomic era.
Article
Biology
Giovanni Annona, Iori Sato, Juan Pascual-Anaya, David Osca, Ingo Braasch, Randal Voss, Jan Stundl, Vladimir Soukup, Allyse Ferrara, Quenton Fontenot, Shigeru Kuratani, John H. Postlethwait, Salvatore D'Aniello
Summary: Nitric oxide (NO) is a crucial signaling molecule in biological systems, playing important roles in cardiovascular, neurological, and immune functions. Understanding the evolution of NO synthases (Nos) genes, which produce NO in vivo, is still a puzzle, especially in fish compared to tetrapods. Recent studies have found the presence of nos3 gene, previously considered lost, in spotted gar, changing our perspective on the origin of nos genes. This study explored nos gene evolution in different vertebrate species and revealed lineage-specific gene duplications and losses, independent losses of nos3 in teleost lineages, and the expression of nos genes in the gills of certain gnathostome species. These findings provide insights into the roles and evolutionary history of nos genes.
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2022)
Article
Cell Biology
Toya Motoshima, Ayumi Nagashima, Chihiro Ota, Haruka Oka, Kohei Hosono, Ingo Braasch, Hidenori Nishihara, Akira Kato
Summary: Solute carrier 12 (Slc12) is a family of electroneutral cation-coupled chloride cotransporters. The evolutionary relationship between slc12a10 and ncc3 remains unresolved, and the presence of slc12a10 in mammals has not been clarified. Our results elaborate on the evolution of Nkcc/Ncc subfamily of Slc12 in vertebrates.
PHYSIOLOGICAL GENOMICS
(2023)
Article
Evolutionary Biology
Sabateeshan Mathavarajah, Andrew W. Thompson, Matthew R. Stoyek, T. Alexander Quinn, Stephane Roy, Ingo Braasch, Graham Dellaire
Summary: This study reveals that aquatic vertebrates undergo transcriptional rewiring of innate immune signaling pathways during limb and fin regeneration to promote immune cell recruitment. The study also shows that cGAS-STING pathway and various suppressors of cytosolic DNA play important roles in the regeneration process. The findings provide insights into the molecular mechanisms behind tissue regeneration in aquatic animals.
JOURNAL OF EXPERIMENTAL ZOOLOGY PART B-MOLECULAR AND DEVELOPMENTAL EVOLUTION
(2023)
Article
Multidisciplinary Sciences
Jan Stundl, Megan L. Martik, Donglei Chen, Desingu Ayyappa Raja, Roman Franek, Anna Pospisilova, Martin Psenicka, Brian D. Metscher, Ingo Braasch, Tatjana Haitina, Robert Cerny, Per E. Ahlberg, Marianne E. Bronner
Summary: Neural crest cells in ray-finned fish can differentiate into osteoblasts that form the bony part of the dermal armor, and these cells retain a neural crest gene signature. This discovery is significant for understanding the origin and evolution of skeletal structures.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Editorial Material
Fisheries
John H. Postlethwait, Ingo Braasch
ZEBRAFISH IN BIOMEDICAL RESEARCH: BIOLOGY, HUSBANDRY, DISEASES, AND RESEARCH APPLICATIONS
(2020)